Reactome | HNP1-4 are stored in primary neutrophil granules

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HNP1-4 are stored in primary neutrophil granules Show undefined attributes

authored	[InstanceEdit:1254178] Jupe, S, 2011-04-28
category	transition
compartment	[Compartment:1470028] azurophil granule lumen [Compartment:17963] Golgi lumen
created	[InstanceEdit:1461974] Jupe, S, 2011-07-27
dbId	1462003
displayName	HNP1-4 are stored in primary neutrophil granules
edited	[InstanceEdit:1461956] Jupe, S, 2011-07-27
eventOf	[Pathway:R-HSA-1462054] Alpha-defensins - Homo sapiens
followingEvent	[Reaction:R-HSA-1462041] HNP1-4 are released into phagocytic vacuoles - Homo sapiens
input	[CandidateSet:R-HSA-1470042] Defensins alpha 1-4 [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1472820] Defensins. Natural peptide antibiotics of human neutrophils [LiteratureReference:1472834] Purification and characterization of human neutrophil peptide 4, a novel member of the defensin family
maxDepth	1
modified	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
name	HNP1-4 are stored in primary neutrophil granules
orthologousEvent	[Reaction:R-MMU-1462003] HNP1-4 are stored in primary neutrophil granules - Mus musculus [Reaction:R-RNO-1462003] HNP1-4 are stored in primary neutrophil granules - Rattus norvegicus
output	[CandidateSet:R-HSA-1470049] Defensins alpha 1-4 [azurophil granule lumen]
precedingEvent	[Reaction:R-HSA-1462039] Pro-HNP1-4 are cleaved to biologically active defensin - Homo sapiens
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1966942] McDermott, AM, 2011-11-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1462003
summation	[Summation:1470040] Alpha defensins HNP1-4, the neutrophil defensins, are stored...

Referrals

(hasEvent)	[Pathway:R-HSA-1462054] Alpha-defensins
(precedingEvent)	[Reaction:R-HSA-1462041] HNP1-4 are released into phagocytic vacuoles

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