Reactome | DREAM complex [nucleoplasm]

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DREAM complex [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-8964464] DREAM complex:PCNA gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8964465] DREAM complex binds the PCNA gene promoter - Homo sapiens [Reaction:R-HSA-8964482] DREAM complex binds the E2F1 gene promoter - Homo sapiens [Reaction:R-HSA-8964492] DREAM complex binds the RBL1 gene promoter - Homo sapiens [Reaction:R-HSA-8964475] DREAM complex binds the TOP2A gene promoter - Homo sapiens [Reaction:R-HSA-8964498] DREAM complex binds the CDC6 gene promoter - Homo sapiens [Reaction:R-HSA-8964471] DREAM complex binds the CDC25A gene promoter - Homo sapiens
created	[InstanceEdit:1362263] Orlic-Milacic, Marija, 2011-06-07
dbId	1362264
displayName	DREAM complex [nucleoplasm]
hasComponent	[Complex:R-HSA-1362259] p-MuvB complex [nucleoplasm] [Complex:R-HSA-1226089] RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-1362264] DREAM complex [nucleoplasm] - Mus musculus [Complex:R-RNO-1362264] DREAM complex [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-1362264] DREAM complex [nucleoplasm] - Canis familiaris [Complex:R-BTA-1362264] DREAM complex [nucleoplasm] - Bos taurus [Complex:R-SSC-1362264] DREAM complex [nucleoplasm] - Sus scrofa [Complex:R-DRE-1362264] DREAM complex [nucleoplasm] - Danio rerio [Complex:R-XTR-1362264] DREAM complex [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-1362264] DREAM complex [nucleoplasm] - Gallus gallus [Complex:R-DME-1362264] DREAM complex [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-1362264] DREAM complex [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-1362264] DREAM complex [nucleoplasm] - Dictyostelium discoideum
isChimeric	false
literatureReference	[LiteratureReference:1362256] Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
maxDepth	4
modified	[InstanceEdit:8964461] Orlic-Milacic, Marija, 2017-02-17
name	DREAM complex
producedByEvent	[Reaction:R-HSA-1362261] p130 (RBL2) associates with MuvB to form DREAM complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1362264
updateTrackers	[UpdateTracker:9894144] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v56:[updateContainedComponent] [UpdateTracker:9888669] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v47:[updateContainedComponent] [UpdateTracker:9896356] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v60:[addLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9894144] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v56:[updateContainedComponent] [UpdateTracker:9888669] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v47:[updateContainedComponent] [UpdateTracker:9896356] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v60:[addLiteratureReference]
(activeUnit)	[NegativeGeneExpressionRegulation:R-HSA-8964532] Negative gene expression regulation by 'DREAM complex:TOP2A gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8964518] Negative gene expression regulation by 'DREAM complex:PCNA gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8964514] Negative gene expression regulation by 'DREAM complex:E2F1 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8964523] Negative gene expression regulation by 'DREAM complex:RBL1 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8964507] Negative gene expression regulation by 'DREAM complex:CDC6 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8964503] Negative gene expression regulation by 'DREAM complex:CDC25A gene [nucleoplasm]'
(hasComponent)	[Complex:R-HSA-8964464] DREAM complex:PCNA gene [nucleoplasm] [Complex:R-HSA-8964483] DREAM complex:E2F1 gene [nucleoplasm] [Complex:R-HSA-8964487] DREAM complex:RBL1 gene [nucleoplasm] [Complex:R-HSA-8964478] DREAM complex:TOP2A gene [nucleoplasm] [Complex:R-HSA-8964499] DREAM complex:CDC6 gene [nucleoplasm] [Complex:R-HSA-8964470] DREAM complex:CDC25A gene [nucleoplasm]
(input)	[Reaction:R-HSA-8964465] DREAM complex binds the PCNA gene promoter [Reaction:R-HSA-8964482] DREAM complex binds the E2F1 gene promoter [Reaction:R-HSA-8964492] DREAM complex binds the RBL1 gene promoter [Reaction:R-HSA-8964475] DREAM complex binds the TOP2A gene promoter [Reaction:R-HSA-8964498] DREAM complex binds the CDC6 gene promoter [Reaction:R-HSA-8964471] DREAM complex binds the CDC25A gene promoter
(output)	[Reaction:R-HSA-1362261] p130 (RBL2) associates with MuvB to form DREAM complex

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