Reactome | DREAM complex binds the PCNA gene promoter

Schema > Reaction > Entries

authored	[InstanceEdit:1363332] Orlic-Milacic, Marija, 2011-06-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8964463] Orlic-Milacic, Marija, 2017-02-17
dbId	8964465
displayName	DREAM complex binds the PCNA gene promoter
edited	[InstanceEdit:8961898] Orlic-Milacic, Marija, 2017-02-06
eventOf	[Pathway:R-HSA-1362277] Transcription of E2F targets under negative control by DREAM complex - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8961665] PCNA gene expression is stimulated by E2F1 and repressed by the DREAM complex - Homo sapiens
input	[Complex:R-HSA-1362264] DREAM complex [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8961653] PCNA gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1362256] Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	DREAM complex binds the PCNA gene promoter
output	[Complex:R-HSA-8964464] DREAM complex:PCNA gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-1362261] p130 (RBL2) associates with MuvB to form DREAM complex - Homo sapiens
releaseDate	2011-09-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1538129] MacPherson, D, 2011-08-25
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8964465
summation	[Summation:8964462] The DREAM complex binds the promoter of the PCNA gene (Litov...

(precedingEvent)	[BlackBoxEvent:R-HSA-8961665] PCNA gene expression is stimulated by E2F1 and repressed by the DREAM complex
(hasEvent)	[Pathway:R-HSA-1362277] Transcription of E2F targets under negative control by DREAM complex

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