Reactome | PDE4A,C,D hydrolyse cAMP

Schema > Reaction > Entries

PDE4A,C,D hydrolyse cAMP Show undefined attributes

catalystActivity	[CatalystActivity:10112181] 3',5'-cyclic-AMP phosphodiesterase activity of PDE4A,C,D [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10112183
displayName	PDE4A,C,D hydrolyse cAMP
eventOf	[Pathway:R-RNO-180024] DARPP-32 events - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-111962] PDE4A,C,D hydrolyse cAMP - Homo sapiens
input	[SimpleEntity:R-ALL-30389] cAMP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PDE4A,C,D hydrolyse cAMP
output	[SimpleEntity:R-ALL-76577] AMP [cytosol]
precedingEvent	[Reaction:R-RNO-111930] Adenylate cyclase produces cAMP - Rattus norvegicus [Reaction:R-RNO-170676] Adenylate cyclase converts ATP into cyclic AMP - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-111962
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-180024] DARPP-32 events
(inferredTo)	[Reaction:R-HSA-111962] PDE4A,C,D hydrolyse cAMP

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