Reactome | Abortive HIV-1 initiation after formation of the first phosphodiester bond

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Abortive HIV-1 initiation after formation of the first phosphodiester bond Show undefined attributes

authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167476] Matthews, L, 2005-10-18 12:38:13
dbId	167477
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Abortive HIV-1 initiation after formation of the first phosphodiester bond
edited	[InstanceEdit:167401] Matthews, L, 2005-10-15 23:27:00
eventOf	[Pathway:R-HSA-167161] HIV Transcription Initiation - Homo sapiens
inferredFrom	[Reaction:R-HSA-73946] Abortive initiation after formation of the first phosphodiester bond - Homo sapiens
input	[Complex:R-HSA-167101] HIV-1 transcription complex [nucleoplasm]
isInDisease	true
isInferred	true
literatureReference	[LiteratureReference:110396] Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter.
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Abortive HIV-1 initiation after formation of the first phosphodiester bond
output	[EntityWithAccessionedSequence:R-HSA-65888] GTF2B [nucleoplasm] [GenomeEncodedEntity:R-HIV-167096] HIV-1 template DNA with first transcript dinucleotide, opened to +8 position [nucleoplasm] [Complex:R-HSA-71307] RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] [Complex:R-HSA-109629] TFIIA [nucleoplasm] [Complex:R-HSA-109626] TFIID [nucleoplasm] [Complex:R-HSA-109633] TFIIE [nucleoplasm] [Complex:R-HSA-109634] TFIIH [nucleoplasm]
precedingEvent	[Reaction:R-HSA-167134] Newly formed phosphodiester bond stabilized and PPi released - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-01-23
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-167477
summation	[Summation:178356] At the beginning of this reaction, 1 molecule of 'HIV-1 tran...

Referrals

(hasEvent)	[Pathway:R-HSA-167161] HIV Transcription Initiation
(inferredTo)	[Reaction:R-HSA-73946] Abortive initiation after formation of the first phosphodiester bond

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