Reactome | Abortive initiation after formation of the first phosphodiester bond

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Abortive initiation after formation of the first phosphodiester bond Show undefined attributes

category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
dbId	73946
displayName	Abortive initiation after formation of the first phosphodiester bond
eventOf	[Pathway:R-HSA-674695] RNA Polymerase II Pre-transcription Events - Homo sapiens
input	[Complex:R-HSA-109878] pol II transcription complex [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:110396] Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter.
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	Abortive initiation after formation of the first phosphodiester bond
orthologousEvent	[Reaction:R-HSA-167477] Abortive HIV-1 initiation after formation of the first phosphodiester bond - Homo sapiens [Reaction:R-SCE-73946] Abortive initiation after formation of the first phosphodiester bond - Saccharomyces cerevisiae [Reaction:R-SPO-73946] Abortive initiation after formation of the first phosphodiester bond - Schizosaccharomyces pombe [Reaction:R-DDI-73946] Abortive initiation after formation of the first phosphodiester bond - Dictyostelium discoideum [Reaction:R-CEL-73946] Abortive initiation after formation of the first phosphodiester bond - Caenorhabditis elegans [Reaction:R-DME-73946] Abortive initiation after formation of the first phosphodiester bond - Drosophila melanogaster [Reaction:R-GGA-73946] Abortive initiation after formation of the first phosphodiester bond - Gallus gallus [Reaction:R-SSC-73946] Abortive initiation after formation of the first phosphodiester bond - Sus scrofa [Reaction:R-BTA-73946] Abortive initiation after formation of the first phosphodiester bond - Bos taurus [Reaction:R-CFA-73946] Abortive initiation after formation of the first phosphodiester bond - Canis familiaris [Reaction:R-RNO-73946] Abortive initiation after formation of the first phosphodiester bond - Rattus norvegicus [Reaction:R-MMU-73946] Abortive initiation after formation of the first phosphodiester bond - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-65888] GTF2B [nucleoplasm] [Complex:R-HSA-71307] RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] [OtherEntity:R-ALL-109877] template DNA with first transcript dinucleotide, opened to +8 position [nucleoplasm] [Complex:R-HSA-109629] TFIIA [nucleoplasm] [Complex:R-HSA-109626] TFIID [nucleoplasm] [Complex:R-HSA-109633] TFIIE [nucleoplasm] [Complex:R-HSA-109634] TFIIH [nucleoplasm]
precedingEvent	[Reaction:R-HSA-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-73946
summation	[Summation:178359] At the beginning of this reaction, 1 molecule of 'pol II tra...

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[Pathway:R-HSA-674695] RNA Polymerase II Pre-transcription Events

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