Reactome | Sphingolipid metabolism

authored	[InstanceEdit:433625] D'Eustachio, P, 2009-08-22
created	[InstanceEdit:433625] D'Eustachio, P, 2009-08-22
dbId	433584
displayName	Sphingolipid metabolism
doi	10.3180/REACT_116113.1
edited	[InstanceEdit:433625] D'Eustachio, P, 2009-08-22
eventOf	[Pathway:R-GGA-372442] Lipid metabolism - Gallus gallus
goBiologicalProcess	[GO_BiologicalProcess:5272] sphingolipid metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-GGA-433550] palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 - Gallus gallus [Reaction:R-GGA-433576] 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ - Gallus gallus [Reaction:R-GGA-433592] sphinganine + stearyl-CoA => dihydroceramide + CoASH - Gallus gallus [Reaction:R-GGA-433599] dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O - Gallus gallus [Reaction:R-GGA-433593] dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O - Gallus gallus [Reaction:R-GGA-433608] ceramide + H2O => stearate + sphingosine [endoplasmic reticulum] - Gallus gallus [Reaction:R-GGA-433578] phytoceramide + H2O => stearate + phytosphingosine - Gallus gallus [Reaction:R-GGA-433606] sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP - Gallus gallus
isInDisease	false
isInferred	false
lastUpdatedDate	2018-03-26
maxDepth	2
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Sphingolipid metabolism
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:433625] D'Eustachio, P, 2009-08-22
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-433584
summation	[Summation:433535] Sphingolipids are derivatives of sphingosine (trans-1,3-dihy...
updateTrackers	[UpdateTracker:9782613] Update Tracker - [Pathway:433584] Sphingolipid metabolism - v59:[updateContainedRLE] [UpdateTracker:9784673] Update Tracker - [Pathway:433584] Sphingolipid metabolism - v53:[updateContainedRLE] [UpdateTracker:9783190] Update Tracker - [Pathway:433584] Sphingolipid metabolism - v57:[updateContainedRLE] [UpdateTracker:9788585] Update Tracker - [Pathway:433584] Sphingolipid metabolism - v41:[updateContainedRLE] [UpdateTracker:9779907] Update Tracker - [Pathway:433584] Sphingolipid metabolism - v64:[updateContainedRLE]

Sphingolipid metabolism Show undefined attributes

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