Reactome | Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13

Schema > BlackBoxEvent > Entries

Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 Show undefined attributes

catalystActivity	[CatalystActivity:10771569] metalloendopeptidase activity of MMP1-3, 7-9, 12, 13 [extracellular region]
category	omitted
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10771571
displayName	Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13
eventOf	[Pathway:R-GGA-1442490] Collagen degradation - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 - Homo sapiens
input	[DefinedSet:R-GGA-2537527] Cleaved collagen fibrils [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13
precedingEvent	[Reaction:R-GGA-1474213] Collagen type III degradation by MMP1,8,9,13 - Gallus gallus [Reaction:R-GGA-1474210] Collagen type III degradation by MMP14 - Gallus gallus [Reaction:R-GGA-1564142] Collagen type IV degradation by MMP2,3,4,9,10,12 - Gallus gallus [Reaction:R-GGA-2168046] Collagen type XII degradation by MMP12 - Gallus gallus [BlackBoxEvent:R-GGA-2473584] Collagen type III degradation by MMP15 - Gallus gallus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49591] Gallus gallus
stId	R-GGA-1454757
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1442490] Collagen degradation
(inferredTo)	[BlackBoxEvent:R-HSA-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13

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