Reactome | Collagen type IV degradation by MMP2,3,4,9,10,12

Schema > Reaction > Entries

Collagen type IV degradation by MMP2,3,4,9,10,12 Show undefined attributes

catalystActivity	[CatalystActivity:10772814] metalloendopeptidase activity of MMP2,3,4,9,10,12 [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10772816
displayName	Collagen type IV degradation by MMP2,3,4,9,10,12
eventOf	[Pathway:R-GGA-1442490] Collagen degradation - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-GGA-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 - Gallus gallus
inferredFrom	[Reaction:R-HSA-1564142] Collagen type IV degradation by MMP2,3,4,9,10,12 - Homo sapiens
input	[DefinedSet:R-GGA-2564668] Collagen IV [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Collagen type IV degradation by MMP2,3,4,9,10,12
output	[DefinedSet:R-GGA-2564684] Cleaved collagen type IV networks [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-1564142
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1442490] Collagen degradation
(precedingEvent)	[BlackBoxEvent:R-GGA-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13
(inferredTo)	[Reaction:R-HSA-1564142] Collagen type IV degradation by MMP2,3,4,9,10,12

Cite Us!