Reactome | fadd [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DRE-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] - Danio rerio [Complex:R-DRE-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] - Danio rerio [Complex:R-DRE-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - Danio rerio [Complex:R-DRE-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - Danio rerio [Complex:R-DRE-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Danio rerio [Complex:R-DRE-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Danio rerio
consumedByEvent	[Reaction:R-DRE-75187] TRAIL:TRAIL receptor trimers bind FADD - Danio rerio [Reaction:R-DRE-75187] TRAIL:TRAIL receptor trimers bind FADD - Danio rerio [Reaction:R-DRE-140978] TRADD:TRAF2:RIP1 binds FADD - Danio rerio [Reaction:R-DRE-140978] TRADD:TRAF2:RIP1 binds FADD - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10563670
displayName	fadd [cytosol]
endCoordinate	208
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-54639] FADD [cytosol] - Homo sapiens
maxDepth	1
name	fadd FADD A0A0R4IXF0
referenceEntity	[ReferenceGeneProduct:uniprot:A0A0R4IXF0] UniProt:A0A0R4IXF0
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68323] Danio rerio
stId	R-DRE-54639
startCoordinate	1

(hasComponent)	[Complex:R-DRE-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] [Complex:R-DRE-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] [Complex:R-DRE-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] [Complex:R-DRE-140977] TRADD:TRAF2:RIPK1:FADD [cytosol] [Complex:R-DRE-2562542] activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane]
(input)	[Reaction:R-DRE-75187] TRAIL:TRAIL receptor trimers bind FADD [Reaction:R-DRE-140978] TRADD:TRAF2:RIP1 binds FADD
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-54639] FADD [cytosol]