Reactome | TNFSF10:TNFRSF10A,B:FADD [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DRE-5637463] TNFSF10:TNFRSF10A,B:FADD:CASP10(1-521) [plasma membrane] - Danio rerio [Complex:R-DRE-3371390] TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR [plasma membrane] - Danio rerio
consumedByEvent	[Reaction:R-DRE-141316] TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10 - Danio rerio [Reaction:R-DRE-75146] TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10564874
displayName	TNFSF10:TNFRSF10A,B:FADD [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-DRE-54639] fadd [cytosol] [Complex:R-DRE-5637469] TNFSF10:TNFRSF10A,B Trimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] - Homo sapiens
maxDepth	4
memberOf	[DefinedSet:R-DRE-2671814] DISC [plasma membrane] - Danio rerio
name	TNFSF10:TNFRSF10A,B:FADD
producedByEvent	[Reaction:R-DRE-75187] TRAIL:TRAIL receptor trimers bind FADD - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-5637464
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DRE-141316] TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10 [Reaction:R-DRE-75146] TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8
(hasComponent)	[Complex:R-DRE-5637463] TNFSF10:TNFRSF10A,B:FADD:CASP10(1-521) [plasma membrane] [Complex:R-DRE-3371390] TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR [plasma membrane] [Complex:R-DRE-5637468] TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] [Complex:R-DRE-2671816] TNFSF10:TNFRSF10A,B:FADD:2xCASP8(1-479) [plasma membrane]
(output)	[Reaction:R-DRE-75187] TRAIL:TRAIL receptor trimers bind FADD
(hasMember)	[DefinedSet:R-DRE-2671814] DISC [plasma membrane]
(inferredTo)	[Complex:R-HSA-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane]