Reactome | S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2

Schema > Reaction > Entries

S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 Show undefined attributes

catalystActivity	[CatalystActivity:10578613] adenosylmethionine decarboxylase activity of AMD1(1-67) [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10578615
displayName	S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2
eventOf	[Pathway:R-DRE-351202] Metabolism of polyamines - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-351215] Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine - Danio rerio [Reaction:R-DRE-351210] dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine - Danio rerio
inferredFrom	[Reaction:R-HSA-351222] S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 - Homo sapiens
input	[SimpleEntity:R-ALL-71284] AdoMet [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 S-adenosyl-L-methionine + H(+) => S-adenosyl 3-(methylsulfanyl)propylamine + CO2
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [SimpleEntity:R-ALL-353113] dc-AdoMet [cytosol]
precedingEvent	[Reaction:R-DRE-174391] MAT1A multimers transfer Ado from ATP to L-Met - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-351222
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-351202] Metabolism of polyamines
(precedingEvent)	[Reaction:R-DRE-351210] dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine [Reaction:R-DRE-351215] Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine
(inferredTo)	[Reaction:R-HSA-351222] S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2

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