Reactome | Metabolism of polyamines

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Metabolism of polyamines Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10647554
displayName	Metabolism of polyamines
eventOf	[Pathway:R-DRE-71291] Metabolism of amino acids and derivatives - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9863] polyamine metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DRE-351143] Agmatine biosynthesis - Danio rerio [Reaction:R-DRE-9955574] ODC dimerizes - Danio rerio [Reaction:R-DRE-70692] ornithine => putrescine + CO2 - Danio rerio [Reaction:R-DRE-351222] S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 - Danio rerio [Reaction:R-DRE-351215] Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine - Danio rerio [Reaction:R-DRE-351210] dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine - Danio rerio [Pathway:R-DRE-351200] Interconversion of polyamines - Danio rerio [Pathway:R-DRE-350562] Regulation of ornithine decarboxylase (ODC) - Danio rerio
inferredFrom	[Pathway:R-HSA-351202] Metabolism of polyamines - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Metabolism of polyamines
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-351202
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-71291] Metabolism of amino acids and derivatives
(inferredTo)	[Pathway:R-HSA-351202] Metabolism of polyamines