Reactome | m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-COV-9694458] SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] - Severe acute respiratory syndrome coronavirus 2 [Complex:R-HSA-9698376] ZCRB1:m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-9694274] mRNA1 is translated to pp1ab - Homo sapiens [BlackBoxEvent:R-HSA-9694334] mRNA1 is translated to pp1a - Homo sapiens [Reaction:R-HSA-9694677] ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA - Homo sapiens [Reaction:R-HSA-9694455] SUMO-p-N protein dimer binds genomic RNA - Homo sapiens [Reaction:R-HSA-9694454] Replication transcription complex binds SARS-CoV-2 genomic RNA - Homo sapiens
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
crossReference	[DatabaseIdentifier:12020746] Mondo:0100096 [DatabaseIdentifier:9684638] ChEBI:17851 [DatabaseIdentifier:9684641] ChEBI:133969 [DatabaseIdentifier:9685140] ChEBI:143976 [DatabaseIdentifier:9685520] ChEBI:8756
dbId	9694393
disease	[Disease:9683912] COVID-19
displayName	m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol]
endCoordinate	29903
hasModifiedResidue	[ModifiedNucleotide:9694448] 5'-end (N7-methyl 5'-triphospho-guanosine)-(2'-O-methyl-adenosine)(2?) residue at 1 [ModifiedNucleotide:9694355] Poly(A) at 29903
inDisease	true
inferredFrom	[EntityWithAccessionedSequence:R-COV-9685518] m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] - Human SARS coronavirus
maxDepth	1
modified	[InstanceEdit:9696741] Orlic-Milacic, Marija, 2020-07-28
name	m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) MN908947.3
producedByEvent	[BlackBoxEvent:R-HSA-9694549] RTC completes synthesis of the minus strand genomic RNA complement - Homo sapiens [BlackBoxEvent:R-HSA-9694471] Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) - Homo sapiens [Reaction:R-HSA-9694723] Uncoating of SARS-CoV-2 Genome - Homo sapiens
referenceEntity	[ReferenceRNASequence:nucleotide:MN908947.3] NCBI Nucleotide:MN908947.3 SARS coronavirus, complete genome
referenceType	ReferenceRNASequence
schemaClass	EntityWithAccessionedSequence
species	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
stId	R-COV-9694393
startCoordinate	1
summation	[Summation:9694685] SARS-CoV-2 mRNA2 open reading frame has a length of 3,822 nt...

(hasComponent)	[Complex:R-HSA-9698376] ZCRB1:m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] [Complex:R-COV-9694402] SUMO-p-N dimer:SARS-CoV-2 genomic RNA [endoplasmic reticulum-Golgi intermediate compartment membrane] [Complex:R-COV-9694731] SARS coronavirus 2 gRNA with secondary structure:RTC [double membrane vesicle viral factory outer membrane] [Complex:R-COV-9694458] SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] [Complex:R-COV-9694612] encapsidated SARS-CoV-2 genomic RNA [endoplasmic reticulum-Golgi intermediate compartment membrane] [Complex:R-COV-9694461] encapsidated SARS-CoV-2 genomic RNA (plus strand) [cytosol]
(input)	[Reaction:R-HSA-9694677] ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA [Reaction:R-HSA-9694455] SUMO-p-N protein dimer binds genomic RNA [BlackBoxEvent:R-HSA-9694274] mRNA1 is translated to pp1ab [Reaction:R-HSA-9694454] Replication transcription complex binds SARS-CoV-2 genomic RNA [BlackBoxEvent:R-HSA-9694334] mRNA1 is translated to pp1a
(output)	[BlackBoxEvent:R-HSA-9694549] RTC completes synthesis of the minus strand genomic RNA complement [BlackBoxEvent:R-HSA-9694471] Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) [Reaction:R-HSA-9694723] Uncoating of SARS-CoV-2 Genome
(inferredTo)	[EntityWithAccessionedSequence:R-COV-9685518] m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol]

m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] Show undefined attributes

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