Reactome | Dimerization of LIMK1 by Hsp90

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Dimerization of LIMK1 by Hsp90 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10254693
displayName	Dimerization of LIMK1 by Hsp90
eventOf	[Pathway:R-CFA-399954] Sema3A PAK dependent Axon repulsion - Canis familiaris [Pathway:R-CFA-2029482] Regulation of actin dynamics for phagocytic cup formation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-419645] Dimerization of LIMK1 by Hsp90 - Homo sapiens
input	[DefinedSet:R-CFA-419619] HSP90AA1,HSP90AB1 [cytosol] 2 × [EntityWithAccessionedSequence:R-CFA-399816] phospho-LIMK1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Dimerization of LIMK1 by Hsp90
output	[Complex:R-CFA-419632] pLIMK dimer:HSP-90 [cytosol]
precedingEvent	[Reaction:R-CFA-399952] Phosphorylation of LIMK-1 by PAK - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-419645
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-399954] Sema3A PAK dependent Axon repulsion [Pathway:R-CFA-2029482] Regulation of actin dynamics for phagocytic cup formation
(inferredTo)	[Reaction:R-HSA-419645] Dimerization of LIMK1 by Hsp90