Reactome | phospho-LIMK1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CFA-419632] pLIMK dimer:HSP-90 [cytosol] - Canis familiaris [Complex:R-CFA-419632] pLIMK dimer:HSP-90 [cytosol] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-419645] Dimerization of LIMK1 by Hsp90 - Canis familiaris [Reaction:R-CFA-419645] Dimerization of LIMK1 by Hsp90 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10253931
displayName	phospho-LIMK1 [cytosol]
endCoordinate	647
hasModifiedResidue	[ModifiedResidue:10253929] O-phospho-L-threonine at 508 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-399816] p-T508-LIMK1 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-LIMK1 p-T508-LIMK1 A0A8I3RQZ5
producedByEvent	[Reaction:R-CFA-2029460] PAK1 phosphorylates LIMK1 - Canis familiaris [Reaction:R-CFA-399952] Phosphorylation of LIMK-1 by PAK - Canis familiaris
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8I3RQZ5] UniProt:A0A8I3RQZ5
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49646] Canis familiaris
stId	R-CFA-399816
startCoordinate	1

(output)	[Reaction:R-CFA-2029460] PAK1 phosphorylates LIMK1 [Reaction:R-CFA-399952] Phosphorylation of LIMK-1 by PAK
(input)	[Reaction:R-CFA-419645] Dimerization of LIMK1 by Hsp90
(activeUnit)	[CatalystActivity:10254689] protein serine/threonine kinase activity of pLIMK dimer:HSP-90 [cytosol]
(hasComponent)	[Complex:R-CFA-419632] pLIMK dimer:HSP-90 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-399816] p-T508-LIMK1 [cytosol]

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