Reactome | BRCC3 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-BTA-5683806] p-5S,2T-BRCA1-A Complex [nucleoplasm] - Bos taurus
consumedByEvent	[Reaction:R-BTA-5683385] Formation of BRCA1-A complex at DNA DSBs - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10334073
displayName	BRCC3 [nucleoplasm]
endCoordinate	316
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5682577] BRCC3 [nucleoplasm] - Homo sapiens
maxDepth	1
name	BRCC3 A5PJP6
producedByEvent	[Reaction:R-BTA-5686685] RIF1 and PAX1IP bind TP53BP1 at DNA DSBs - Bos taurus [Reaction:R-BTA-5684071] RNF4 ubiquitinates MDC1 - Bos taurus
referenceEntity	[ReferenceGeneProduct:uniprot:A5PJP6] UniProt:A5PJP6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-5682577
startCoordinate	2

(activeUnit)	[CatalystActivity:10408212] K63-linked deubiquitinase activity of BRISC complex:K63polyUb-NLRP3 [cytosol] [CatalystActivity:10408187] K63-linked deubiquitinase activity of BRCA1-A Complex:K63polyUb-histone H2A [nucleoplasm]
(output)	[Reaction:R-BTA-5686685] RIF1 and PAX1IP bind TP53BP1 at DNA DSBs [Reaction:R-BTA-5684071] RNF4 ubiquitinates MDC1
(hasComponent)	[Complex:R-BTA-5683806] p-5S,2T-BRCA1-A Complex [nucleoplasm] [Complex:R-BTA-5683606] p-4S,2T-BRCA1-A Complex [nucleoplasm] [Complex:R-BTA-5683386] BRCA1-A Complex [nucleoplasm]
(input)	[Reaction:R-BTA-5683385] Formation of BRCA1-A complex at DNA DSBs
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5682577] BRCC3 [nucleoplasm]

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