Reactome | BRCC3 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5683806] p-5S,2T-BRCA1-A Complex [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5683385] Formation of BRCA1-A complex at DNA DSBs - Homo sapiens
created	[InstanceEdit:5682578] Orlic-Milacic, Marija, 2015-03-09
dbId	5682577
displayName	BRCC3 [nucleoplasm]
endCoordinate	316
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-5682577] BRCC3 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-5682577] BRCC3 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-5682577] FUNDC2 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-5682577] BRCC3 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-5682577] BRCC3 [nucleoplasm] - Sus scrofa [GenomeEncodedEntity:R-DRE-5682577] Ghost homologue of BRCC3 [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-5682577] BRCC3 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-5682577] BRCC3 [nucleoplasm] - Gallus gallus
maxDepth	1
name	BRCC3 Lys-63-specific deubiquitinase BRCC36 BRCC36
producedByEvent	[Reaction:R-HSA-5686685] RIF1 and PAX1IP bind TP53BP1 at DNA DSBs - Homo sapiens [Reaction:R-HSA-5684071] RNF4 ubiquitinates MDC1 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P46736] UniProt:P46736 BRCC3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5682577
startCoordinate	2

(activeUnit)	[CatalystActivity:5691417] K63-linked deubiquitinase activity of BRISC complex:K63polyUb-NLRP3 [cytosol] [CatalystActivity:5691436] K63-linked deubiquitinase activity of BRCA1-A Complex:K63polyUb-histone H2A [nucleoplasm]
(output)	[Reaction:R-HSA-5686685] RIF1 and PAX1IP bind TP53BP1 at DNA DSBs [Reaction:R-HSA-5684071] RNF4 ubiquitinates MDC1
(hasComponent)	[Complex:R-HSA-5683806] p-5S,2T-BRCA1-A Complex [nucleoplasm] [Complex:R-HSA-5683606] p-4S,2T-BRCA1-A Complex [nucleoplasm] [Complex:R-HSA-5683386] BRCA1-A Complex [nucleoplasm]
(input)	[Reaction:R-HSA-5683385] Formation of BRCA1-A complex at DNA DSBs