Reactome | DHCE [endoplasmic reticulum membrane]

Schema > SimpleEntity > Entries

DHCE [endoplasmic reticulum membrane] Show undefined attributes

compartment	[Compartment:12045] endoplasmic reticulum membrane
consumedByEvent	[Reaction:R-GGA-433599] dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O - Gallus gallus [Reaction:R-DDI-428259] DEGS1 dehydrogenates dihydroceramide - Dictyostelium discoideum [Reaction:R-CEL-428259] DEGS1 dehydrogenates dihydroceramide - Caenorhabditis elegans [Reaction:R-DME-428259] DEGS1 dehydrogenates dihydroceramide - Drosophila melanogaster [Reaction:R-GGA-428259] DEGS1 dehydrogenates dihydroceramide - Gallus gallus [Reaction:R-XTR-428259] DEGS1 dehydrogenates dihydroceramide - Xenopus tropicalis [Reaction:R-DRE-428259] DEGS1 dehydrogenates dihydroceramide - Danio rerio [Reaction:R-SSC-428259] DEGS1 dehydrogenates dihydroceramide - Sus scrofa [Reaction:R-BTA-428259] DEGS1 dehydrogenates dihydroceramide - Bos taurus [Reaction:R-CFA-428259] DEGS1 dehydrogenates dihydroceramide - Canis familiaris [Reaction:R-RNO-428259] DEGS1 dehydrogenates dihydroceramide - Rattus norvegicus [Reaction:R-MMU-428259] DEGS1 dehydrogenates dihydroceramide - Mus musculus [Reaction:R-HSA-428259] DEGS1 dehydrogenates dihydroceramide - Homo sapiens [Reaction:R-DDI-428260] DEGS2 oxygenates dihydroceramide - Dictyostelium discoideum [Reaction:R-CEL-428260] DEGS2 oxygenates dihydroceramide - Caenorhabditis elegans [Reaction:R-DME-428260] DEGS2 oxygenates dihydroceramide - Drosophila melanogaster [Reaction:R-GGA-428260] DEGS2 oxygenates dihydroceramide - Gallus gallus [Reaction:R-XTR-428260] DEGS2 oxygenates dihydroceramide - Xenopus tropicalis [Reaction:R-DRE-428260] DEGS2 oxygenates dihydroceramide - Danio rerio [Reaction:R-SSC-428260] DEGS2 oxygenates dihydroceramide - Sus scrofa [Reaction:R-BTA-428260] DEGS2 oxygenates dihydroceramide - Bos taurus [Reaction:R-CFA-428260] DEGS2 oxygenates dihydroceramide - Canis familiaris [Reaction:R-RNO-428260] DEGS2 oxygenates dihydroceramide - Rattus norvegicus [Reaction:R-MMU-428260] DEGS2 oxygenates dihydroceramide - Mus musculus [Reaction:R-HSA-428260] DEGS2 oxygenates dihydroceramide - Homo sapiens [Reaction:R-GGA-433593] dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O - Gallus gallus
created	[InstanceEdit:428151] D'Eustachio, P, 2009-07-02
dbId	428126
displayName	DHCE [endoplasmic reticulum membrane]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9842382] Stephan, Ralf, 2023-08-27
name	DHCE dihydroceramide N-acylsphingoid
producedByEvent	[Reaction:R-PFA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Plasmodium falciparum [Reaction:R-SCE-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Saccharomyces cerevisiae [Reaction:R-SPO-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Schizosaccharomyces pombe [Reaction:R-DDI-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Dictyostelium discoideum [Reaction:R-CEL-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Caenorhabditis elegans [Reaction:R-DME-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Drosophila melanogaster [Reaction:R-GGA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Gallus gallus [Reaction:R-XTR-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Xenopus tropicalis [Reaction:R-DRE-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Danio rerio [Reaction:R-SSC-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Sus scrofa [Reaction:R-BTA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Bos taurus [Reaction:R-CFA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Canis familiaris [Reaction:R-RNO-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Rattus norvegicus [Reaction:R-MMU-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Mus musculus [Reaction:R-HSA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid - Homo sapiens [Reaction:R-GGA-433592] sphinganine + stearyl-CoA => dihydroceramide + CoASH - Gallus gallus
referenceEntity	[ReferenceMolecule:chebi:139048] dihydroceramide [ChEBI:139048]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-428126
updateTrackers	[UpdateTracker:9874356] Update Tracker - [SimpleEntity:428126] DHCE [endoplasmic reticulum membrane] - v43:[addName] [UpdateTracker:9906431] Update Tracker - [SimpleEntity:428126] DHCE [endoplasmic reticulum membrane] - v87:[add_removeReferenceEntity, modifyName] [UpdateTracker:9898927] Update Tracker - [SimpleEntity:428126] DHCE [endoplasmic reticulum membrane] - v64:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9874356] Update Tracker - [SimpleEntity:428126] DHCE [endoplasmic reticulum membrane] - v43:[addName] [UpdateTracker:9906431] Update Tracker - [SimpleEntity:428126] DHCE [endoplasmic reticulum membrane] - v87:[add_removeReferenceEntity, modifyName] [UpdateTracker:9898927] Update Tracker - [SimpleEntity:428126] DHCE [endoplasmic reticulum membrane] - v64:[addName]
(input)	[Reaction:R-GGA-433593] dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O [Reaction:R-GGA-433599] dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O [Reaction:R-DDI-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-CEL-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-DME-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-GGA-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-XTR-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-DRE-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-SSC-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-BTA-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-CFA-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-RNO-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-MMU-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-HSA-428259] DEGS1 dehydrogenates dihydroceramide [Reaction:R-DDI-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-CEL-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-DME-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-GGA-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-XTR-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-DRE-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-SSC-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-BTA-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-CFA-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-RNO-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-MMU-428260] DEGS2 oxygenates dihydroceramide [Reaction:R-HSA-428260] DEGS2 oxygenates dihydroceramide
(output)	[Reaction:R-GGA-433592] sphinganine + stearyl-CoA => dihydroceramide + CoASH [Reaction:R-PFA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-SCE-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-SPO-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-DDI-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-CEL-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-DME-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-GGA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-XTR-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-DRE-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-SSC-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-BTA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-CFA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-RNO-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-MMU-428185] Ceramide synthases transfer acyl-CoA onto sphingoid [Reaction:R-HSA-428185] Ceramide synthases transfer acyl-CoA onto sphingoid

© 2026 Reactome

Cite Us!