Reactome | GlcA [cytosol]

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GlcA [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-6785668] Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA - Homo sapiens
created	[InstanceEdit:2162230] Jassal, B, 2012-03-16
dbId	2162232
displayName	GlcA [cytosol]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9966597] Stephan, Ralf, 2025-09-22
name	GlcA D-glucuronic acid D-glucuronate
producedByEvent	[Reaction:R-DDI-5678327] MIOX oxidises Ins to GlcA - Dictyostelium discoideum [Reaction:R-CEL-5678327] MIOX oxidises Ins to GlcA - Caenorhabditis elegans [Reaction:R-DME-5678327] MIOX oxidises Ins to GlcA - Drosophila melanogaster [Reaction:R-GGA-5678327] MIOX oxidises Ins to GlcA - Gallus gallus [Reaction:R-XTR-5678327] MIOX oxidises Ins to GlcA - Xenopus tropicalis [Reaction:R-DRE-5678327] MIOX oxidises Ins to GlcA - Danio rerio [Reaction:R-SSC-5678327] MIOX oxidises Ins to GlcA - Sus scrofa [Reaction:R-BTA-5678327] MIOX oxidises Ins to GlcA - Bos taurus [Reaction:R-CFA-5678327] MIOX oxidises Ins to GlcA - Canis familiaris [Reaction:R-RNO-5678327] MIOX oxidises Ins to GlcA - Rattus norvegicus [Reaction:R-MMU-5678327] MIOX oxidises Ins to GlcA - Mus musculus [Reaction:R-HSA-5678327] MIOX oxidises Ins to GlcA - Homo sapiens [Reaction:R-DDI-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Dictyostelium discoideum [Reaction:R-CEL-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Caenorhabditis elegans [Reaction:R-DME-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Drosophila melanogaster [Reaction:R-GGA-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Gallus gallus [Reaction:R-XTR-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Xenopus tropicalis [Reaction:R-DRE-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Danio rerio [Reaction:R-SSC-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Sus scrofa [Reaction:R-CFA-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Canis familiaris [Reaction:R-RNO-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Rattus norvegicus [Reaction:R-MMU-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Mus musculus [Reaction:R-HSA-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Homo sapiens [Reaction:R-BTA-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol - Bos taurus [BlackBoxEvent:R-RNO-9756183] UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL - Rattus norvegicus [BlackBoxEvent:R-MMU-9756183] UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL - Mus musculus [BlackBoxEvent:R-HSA-9756183] UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL - Homo sapiens [BlackBoxEvent:R-RNO-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Rattus norvegicus [BlackBoxEvent:R-MMU-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Mus musculus [BlackBoxEvent:R-HSA-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL - Homo sapiens [BlackBoxEvent:R-RNO-9756156] UGT1A3 lactonizes ATV to ATVL - Rattus norvegicus [BlackBoxEvent:R-MMU-9756156] UGT1A3 lactonizes ATV to ATVL - Mus musculus [BlackBoxEvent:R-HSA-9756156] UGT1A3 lactonizes ATV to ATVL - Homo sapiens
referenceEntity	[ReferenceMolecule:chebi:58720] D-glucopyranuronate [ChEBI:58720]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-2162232
updateTrackers	[UpdateTracker:9892387] Update Tracker - [SimpleEntity:2162232] GlcA [cytosol] - v53:[add_removeReferenceEntity] [UpdateTracker:9891644] Update Tracker - [SimpleEntity:2162232] GlcA [cytosol] - v52:[addName] [UpdateTracker:9972677] Update Tracker - [SimpleEntity:2162232] GlcA [cytosol] - v95:[add_removeReferenceEntity]

Referrals

(updatedInstance)	[UpdateTracker:9892387] Update Tracker - [SimpleEntity:2162232] GlcA [cytosol] - v53:[add_removeReferenceEntity] [UpdateTracker:9891644] Update Tracker - [SimpleEntity:2162232] GlcA [cytosol] - v52:[addName] [UpdateTracker:9972677] Update Tracker - [SimpleEntity:2162232] GlcA [cytosol] - v95:[add_removeReferenceEntity]
(output)	[Reaction:R-DDI-5678327] MIOX oxidises Ins to GlcA [Reaction:R-CEL-5678327] MIOX oxidises Ins to GlcA [Reaction:R-DME-5678327] MIOX oxidises Ins to GlcA [Reaction:R-GGA-5678327] MIOX oxidises Ins to GlcA [Reaction:R-XTR-5678327] MIOX oxidises Ins to GlcA [Reaction:R-DRE-5678327] MIOX oxidises Ins to GlcA [Reaction:R-SSC-5678327] MIOX oxidises Ins to GlcA [Reaction:R-BTA-5678327] MIOX oxidises Ins to GlcA [Reaction:R-CFA-5678327] MIOX oxidises Ins to GlcA [Reaction:R-RNO-5678327] MIOX oxidises Ins to GlcA [Reaction:R-MMU-5678327] MIOX oxidises Ins to GlcA [Reaction:R-HSA-5678327] MIOX oxidises Ins to GlcA [BlackBoxEvent:R-RNO-9756183] UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL [BlackBoxEvent:R-MMU-9756183] UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL [BlackBoxEvent:R-HSA-9756183] UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL [BlackBoxEvent:R-RNO-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL [BlackBoxEvent:R-MMU-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL [BlackBoxEvent:R-HSA-9756134] UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL [BlackBoxEvent:R-RNO-9756156] UGT1A3 lactonizes ATV to ATVL [BlackBoxEvent:R-MMU-9756156] UGT1A3 lactonizes ATV to ATVL [BlackBoxEvent:R-HSA-9756156] UGT1A3 lactonizes ATV to ATVL [Reaction:R-DDI-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-CEL-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-DME-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-GGA-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-XTR-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-DRE-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-SSC-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-CFA-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-RNO-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-MMU-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-HSA-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol [Reaction:R-BTA-2162229] SLC17A5 exports GlcA from the lysosome to the cytosol
(input)	[FailedReaction:R-HSA-6785668] Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA

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