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GlcA [cytosol]
Stable Identifier
R-ALL-2162232
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
D-glucuronic acid, D-glucuronate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Inositol phosphate metabolism (Bos taurus)
Synthesis of IP2, IP, and Ins in the cytosol (Bos taurus)
MIOX oxidises Ins to GlcA (Bos taurus)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Bos taurus)
Glycosaminoglycan metabolism (Bos taurus)
Hyaluronan metabolism (Bos taurus)
Hyaluronan degradation (Bos taurus)
SLC17A5 exports GlcA from the lysosome to the cytosol (Bos taurus)
GlcA [cytosol]
Metabolism (Caenorhabditis elegans)
Inositol phosphate metabolism (Caenorhabditis elegans)
Synthesis of IP2, IP, and Ins in the cytosol (Caenorhabditis elegans)
MIOX oxidises Ins to GlcA (Caenorhabditis elegans)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Caenorhabditis elegans)
Glycosaminoglycan metabolism (Caenorhabditis elegans)
Hyaluronan metabolism (Caenorhabditis elegans)
Hyaluronan degradation (Caenorhabditis elegans)
SLC17A5 exports GlcA from the lysosome to the cytosol (Caenorhabditis elegans)
GlcA [cytosol]
Metabolism (Canis familiaris)
Inositol phosphate metabolism (Canis familiaris)
Synthesis of IP2, IP, and Ins in the cytosol (Canis familiaris)
MIOX oxidises Ins to GlcA (Canis familiaris)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Canis familiaris)
Glycosaminoglycan metabolism (Canis familiaris)
Hyaluronan metabolism (Canis familiaris)
Hyaluronan degradation (Canis familiaris)
SLC17A5 exports GlcA from the lysosome to the cytosol (Canis familiaris)
GlcA [cytosol]
Metabolism (Danio rerio)
Inositol phosphate metabolism (Danio rerio)
Synthesis of IP2, IP, and Ins in the cytosol (Danio rerio)
MIOX oxidises Ins to GlcA (Danio rerio)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Danio rerio)
Glycosaminoglycan metabolism (Danio rerio)
Hyaluronan metabolism (Danio rerio)
Hyaluronan degradation (Danio rerio)
SLC17A5 exports GlcA from the lysosome to the cytosol (Danio rerio)
GlcA [cytosol]
Metabolism (Dictyostelium discoideum)
Inositol phosphate metabolism (Dictyostelium discoideum)
Synthesis of IP2, IP, and Ins in the cytosol (Dictyostelium discoideum)
MIOX oxidises Ins to GlcA (Dictyostelium discoideum)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Dictyostelium discoideum)
Glycosaminoglycan metabolism (Dictyostelium discoideum)
Hyaluronan metabolism (Dictyostelium discoideum)
Hyaluronan degradation (Dictyostelium discoideum)
SLC17A5 exports GlcA from the lysosome to the cytosol (Dictyostelium discoideum)
GlcA [cytosol]
Metabolism (Drosophila melanogaster)
Inositol phosphate metabolism (Drosophila melanogaster)
Synthesis of IP2, IP, and Ins in the cytosol (Drosophila melanogaster)
MIOX oxidises Ins to GlcA (Drosophila melanogaster)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Drosophila melanogaster)
Glycosaminoglycan metabolism (Drosophila melanogaster)
Hyaluronan metabolism (Drosophila melanogaster)
Hyaluronan degradation (Drosophila melanogaster)
SLC17A5 exports GlcA from the lysosome to the cytosol (Drosophila melanogaster)
GlcA [cytosol]
Metabolism (Gallus gallus)
Inositol phosphate metabolism (Gallus gallus)
Synthesis of IP2, IP, and Ins in the cytosol (Gallus gallus)
MIOX oxidises Ins to GlcA (Gallus gallus)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Gallus gallus)
Glycosaminoglycan metabolism (Gallus gallus)
Hyaluronan metabolism (Gallus gallus)
Hyaluronan degradation (Gallus gallus)
SLC17A5 exports GlcA from the lysosome to the cytosol (Gallus gallus)
GlcA [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with O-glycosylation of proteins (Homo sapiens)
Defective LARGE causes MDDGA6 and MDDGB6 (Homo sapiens)
Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA (Homo sapiens)
GlcA [cytosol]
Drug ADME (Homo sapiens)
Atorvastatin ADME (Homo sapiens)
UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL (Homo sapiens)
GlcA [cytosol]
UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Homo sapiens)
GlcA [cytosol]
UGT1A3 lactonizes ATV to ATVL (Homo sapiens)
GlcA [cytosol]
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP2, IP, and Ins in the cytosol (Homo sapiens)
MIOX oxidises Ins to GlcA (Homo sapiens)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Hyaluronan metabolism (Homo sapiens)
Hyaluronan degradation (Homo sapiens)
SLC17A5 exports GlcA from the lysosome to the cytosol (Homo sapiens)
GlcA [cytosol]
Drug ADME (Mus musculus)
Atorvastatin ADME (Mus musculus)
UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL (Mus musculus)
GlcA [cytosol]
UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Mus musculus)
GlcA [cytosol]
UGT1A3 lactonizes ATV to ATVL (Mus musculus)
GlcA [cytosol]
Metabolism (Mus musculus)
Inositol phosphate metabolism (Mus musculus)
Synthesis of IP2, IP, and Ins in the cytosol (Mus musculus)
MIOX oxidises Ins to GlcA (Mus musculus)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Mus musculus)
Glycosaminoglycan metabolism (Mus musculus)
Hyaluronan metabolism (Mus musculus)
Hyaluronan degradation (Mus musculus)
SLC17A5 exports GlcA from the lysosome to the cytosol (Mus musculus)
GlcA [cytosol]
Drug ADME (Rattus norvegicus)
Atorvastatin ADME (Rattus norvegicus)
UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL (Rattus norvegicus)
GlcA [cytosol]
UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Rattus norvegicus)
GlcA [cytosol]
UGT1A3 lactonizes ATV to ATVL (Rattus norvegicus)
GlcA [cytosol]
Metabolism (Rattus norvegicus)
Inositol phosphate metabolism (Rattus norvegicus)
Synthesis of IP2, IP, and Ins in the cytosol (Rattus norvegicus)
MIOX oxidises Ins to GlcA (Rattus norvegicus)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Rattus norvegicus)
Glycosaminoglycan metabolism (Rattus norvegicus)
Hyaluronan metabolism (Rattus norvegicus)
Hyaluronan degradation (Rattus norvegicus)
SLC17A5 exports GlcA from the lysosome to the cytosol (Rattus norvegicus)
GlcA [cytosol]
Metabolism (Sus scrofa)
Inositol phosphate metabolism (Sus scrofa)
Synthesis of IP2, IP, and Ins in the cytosol (Sus scrofa)
MIOX oxidises Ins to GlcA (Sus scrofa)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Sus scrofa)
Glycosaminoglycan metabolism (Sus scrofa)
Hyaluronan metabolism (Sus scrofa)
Hyaluronan degradation (Sus scrofa)
SLC17A5 exports GlcA from the lysosome to the cytosol (Sus scrofa)
GlcA [cytosol]
Metabolism (Xenopus tropicalis)
Inositol phosphate metabolism (Xenopus tropicalis)
Synthesis of IP2, IP, and Ins in the cytosol (Xenopus tropicalis)
MIOX oxidises Ins to GlcA (Xenopus tropicalis)
GlcA [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Xenopus tropicalis)
Glycosaminoglycan metabolism (Xenopus tropicalis)
Hyaluronan metabolism (Xenopus tropicalis)
Hyaluronan degradation (Xenopus tropicalis)
SLC17A5 exports GlcA from the lysosome to the cytosol (Xenopus tropicalis)
GlcA [cytosol]
External Reference Information
External Reference
D-glucopyranuronate [ChEBI:58720]
Participates
as an output of
MIOX oxidises Ins to GlcA (Dictyostelium discoideum)
MIOX oxidises Ins to GlcA (Caenorhabditis elegans)
MIOX oxidises Ins to GlcA (Drosophila melanogaster)
MIOX oxidises Ins to GlcA (Gallus gallus)
MIOX oxidises Ins to GlcA (Xenopus tropicalis)
MIOX oxidises Ins to GlcA (Danio rerio)
MIOX oxidises Ins to GlcA (Sus scrofa)
MIOX oxidises Ins to GlcA (Bos taurus)
MIOX oxidises Ins to GlcA (Canis familiaris)
MIOX oxidises Ins to GlcA (Rattus norvegicus)
MIOX oxidises Ins to GlcA (Mus musculus)
MIOX oxidises Ins to GlcA (Homo sapiens)
UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Rattus norvegicus)
UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Mus musculus)
UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Homo sapiens)
UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL (Rattus norvegicus)
UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL (Mus musculus)
UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL (Homo sapiens)
UGT1A3 lactonizes ATV to ATVL (Rattus norvegicus)
UGT1A3 lactonizes ATV to ATVL (Mus musculus)
UGT1A3 lactonizes ATV to ATVL (Homo sapiens)
SLC17A5 exports GlcA from the lysosome to the cytosol (Dictyostelium discoideum)
SLC17A5 exports GlcA from the lysosome to the cytosol (Caenorhabditis elegans)
SLC17A5 exports GlcA from the lysosome to the cytosol (Drosophila melanogaster)
SLC17A5 exports GlcA from the lysosome to the cytosol (Gallus gallus)
SLC17A5 exports GlcA from the lysosome to the cytosol (Xenopus tropicalis)
SLC17A5 exports GlcA from the lysosome to the cytosol (Danio rerio)
SLC17A5 exports GlcA from the lysosome to the cytosol (Bos taurus)
SLC17A5 exports GlcA from the lysosome to the cytosol (Canis familiaris)
SLC17A5 exports GlcA from the lysosome to the cytosol (Rattus norvegicus)
SLC17A5 exports GlcA from the lysosome to the cytosol (Mus musculus)
SLC17A5 exports GlcA from the lysosome to the cytosol (Homo sapiens)
SLC17A5 exports GlcA from the lysosome to the cytosol (Sus scrofa)
as an input of
Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA (Homo sapiens)
Cross References
AraCyc
GLUCURONATE
CAS
6556-12-3
PubChem Compound
16740916
ZINC
ZINC000004213449
,
ZINC000004097543
KEGG Gene
C00191
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