Reactome | MIOX oxidises Ins to GlcA

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MIOX oxidises Ins to GlcA Show undefined attributes

catalystActivity	[CatalystActivity:10968726] inositol oxygenase activity of MIOX:2xFe2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10968728
displayName	MIOX oxidises Ins to GlcA
eventOf	[Pathway:R-CEL-1855183] Synthesis of IP2, IP, and Ins in the cytosol - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5678327] MIOX oxidises Ins to GlcA - Homo sapiens
input	[SimpleEntity:R-ALL-426910] Ins [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MIOX oxidises Ins to GlcA
output	[SimpleEntity:R-ALL-2162232] GlcA [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
precedingEvent	[Reaction:R-CEL-1855210] I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5678327
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-1855183] Synthesis of IP2, IP, and Ins in the cytosol
(inferredTo)	[Reaction:R-HSA-5678327] MIOX oxidises Ins to GlcA