Reactome | FUMA [mitochondrial matrix]

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FUMA [mitochondrial matrix] Show undefined attributes

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-GGA-373145] fumarate + H2O <=> malate - Gallus gallus [Reaction:R-DDI-70982] FH tetramer hydrates fumarate to L-malate - Dictyostelium discoideum [Reaction:R-SCE-70982] FH tetramer hydrates fumarate to L-malate - Saccharomyces cerevisiae [Reaction:R-SPO-70982] FH tetramer hydrates fumarate to L-malate - Schizosaccharomyces pombe [Reaction:R-CEL-70982] FH tetramer hydrates fumarate to L-malate - Caenorhabditis elegans [Reaction:R-GGA-70982] FH tetramer hydrates fumarate to L-malate - Gallus gallus [Reaction:R-DME-70982] FH tetramer hydrates fumarate to L-malate - Drosophila melanogaster [Reaction:R-DRE-70982] FH tetramer hydrates fumarate to L-malate - Danio rerio [Reaction:R-BTA-70982] FH tetramer hydrates fumarate to L-malate - Bos taurus [Reaction:R-CFA-70982] FH tetramer hydrates fumarate to L-malate - Canis familiaris [Reaction:R-RNO-70982] FH tetramer hydrates fumarate to L-malate - Rattus norvegicus [Reaction:R-HSA-70982] FH tetramer hydrates fumarate to L-malate - Homo sapiens [Reaction:R-MMU-70982] FH tetramer hydrates fumarate to L-malate - Mus musculus [Reaction:R-GGA-373129] fumarate + FADH2 <=> succinate + FAD - Gallus gallus
created	[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
crossReference	[DatabaseIdentifier:29587] COMPOUND:C00122
dbId	113588
displayName	FUMA [mitochondrial matrix]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9853494] Stephan, Ralf, 2023-11-16
name	FUMA Fumarate fumaric acid Trans-butenedioic acid
positivelyRegulates	[PositiveRegulation:9854700] Positive regulation by 'FUMA [mitochondrial matrix]' [PositiveRegulation:R-HSA-9012256] Positive regulation by 'FUMA [mitochondrial matrix]'
producedByEvent	[Reaction:R-GGA-373141] malate <=> fumarate + H2O - Gallus gallus [Reaction:R-HSA-163213] Transfer of electrons through the succinate dehydrogenase complex - Homo sapiens [Reaction:R-XTR-70994] SDH complex dehydrogenates succinate - Xenopus tropicalis [Reaction:R-SSC-70994] SDH complex dehydrogenates succinate - Sus scrofa [Reaction:R-DDI-70994] SDH complex dehydrogenates succinate - Dictyostelium discoideum [Reaction:R-SCE-70994] SDH complex dehydrogenates succinate - Saccharomyces cerevisiae [Reaction:R-SPO-70994] SDH complex dehydrogenates succinate - Schizosaccharomyces pombe [Reaction:R-CEL-70994] SDH complex dehydrogenates succinate - Caenorhabditis elegans [Reaction:R-GGA-70994] SDH complex dehydrogenates succinate - Gallus gallus [Reaction:R-DME-70994] SDH complex dehydrogenates succinate - Drosophila melanogaster [Reaction:R-DRE-70994] SDH complex dehydrogenates succinate - Danio rerio [Reaction:R-BTA-70994] SDH complex dehydrogenates succinate - Bos taurus [Reaction:R-CFA-70994] SDH complex dehydrogenates succinate - Canis familiaris [Reaction:R-RNO-70994] SDH complex dehydrogenates succinate - Rattus norvegicus [Reaction:R-HSA-70994] SDH complex dehydrogenates succinate - Homo sapiens [Reaction:R-MMU-70994] SDH complex dehydrogenates succinate - Mus musculus [Reaction:R-GGA-373147] succinate + FAD <=> fumarate + FADH2 - Gallus gallus
referenceEntity	[ReferenceMolecule:chebi:29806] fumarate(2-) [ChEBI:29806]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-113588
updateTrackers	[UpdateTracker:9891676] Update Tracker - [SimpleEntity:113588] FUMA [mitochondrial matrix] - v52:[modifyName] [UpdateTracker:9874137] Update Tracker - [SimpleEntity:113588] FUMA [mitochondrial matrix] - v43:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9891676] Update Tracker - [SimpleEntity:113588] FUMA [mitochondrial matrix] - v52:[modifyName] [UpdateTracker:9874137] Update Tracker - [SimpleEntity:113588] FUMA [mitochondrial matrix] - v43:[addName]
(output)	[Reaction:R-GGA-373147] succinate + FAD <=> fumarate + FADH2 [Reaction:R-GGA-373141] malate <=> fumarate + H2O [Reaction:R-HSA-163213] Transfer of electrons through the succinate dehydrogenase complex [Reaction:R-XTR-70994] SDH complex dehydrogenates succinate [Reaction:R-SSC-70994] SDH complex dehydrogenates succinate [Reaction:R-DDI-70994] SDH complex dehydrogenates succinate [Reaction:R-SCE-70994] SDH complex dehydrogenates succinate [Reaction:R-SPO-70994] SDH complex dehydrogenates succinate [Reaction:R-CEL-70994] SDH complex dehydrogenates succinate [Reaction:R-GGA-70994] SDH complex dehydrogenates succinate [Reaction:R-DME-70994] SDH complex dehydrogenates succinate [Reaction:R-DRE-70994] SDH complex dehydrogenates succinate [Reaction:R-BTA-70994] SDH complex dehydrogenates succinate [Reaction:R-CFA-70994] SDH complex dehydrogenates succinate [Reaction:R-RNO-70994] SDH complex dehydrogenates succinate [Reaction:R-HSA-70994] SDH complex dehydrogenates succinate [Reaction:R-MMU-70994] SDH complex dehydrogenates succinate
(input)	[Reaction:R-GGA-373129] fumarate + FADH2 <=> succinate + FAD [Reaction:R-GGA-373145] fumarate + H2O <=> malate [Reaction:R-DDI-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-SCE-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-SPO-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-CEL-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-GGA-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-DME-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-DRE-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-BTA-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-CFA-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-RNO-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-HSA-70982] FH tetramer hydrates fumarate to L-malate [Reaction:R-MMU-70982] FH tetramer hydrates fumarate to L-malate
(regulator)	[PositiveRegulation:9854700] Positive regulation by 'FUMA [mitochondrial matrix]' [PositiveRegulation:R-HSA-9012256] Positive regulation by 'FUMA [mitochondrial matrix]'

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