Reactome | A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis

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A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis Show undefined attributes

author	[Person:9774479] Boualia, SK [Person:9774519] Gaitan, Y [Person:9754265] Tremblay, M [Person:9754288] Sharma, R [Person:9014699] Cardin, J [Person:8869659] Kania, A [Person:5621532] Bouchard, M
created	[InstanceEdit:9774517] May, Bruce, 2022-05-24
dbId	9774516
displayName	A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
journal	Dev Biol
pages	555-66
pubMedIdentifier	23920117
schemaClass	LiteratureReference
title	A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
url	http://www.ncbi.nlm.nih.gov/pubmed/23920117
volume	382
year	2013

Referrals

(literatureReference)

[Pathway:R-HSA-9830364] Formation of the nephric duct
[Summation:9831408] MECOM (EVI1) is expressed in the nephric duct of the proneph...
[BlackBoxEvent:R-MMU-9830518] Expression of Mecom (Evi1) in the nephric duct
[Summation:9831417] PAX2 binds a conserved region upstream of the transcription ...
[Reaction:R-MMU-9831384] Pax2 binds the Plac8 gene
[Summation:9831434] The Inhibitor of DNA-binding 4 (ID4) gene is expressed in th...
[BlackBoxEvent:R-MMU-9830471] Expression of Id4 in the nephric duct
[RegulationReference:9830434] Positive gene expression regulation by 'Gata3 [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
[Summation:9831426] PCDH19 is strongly expressed in the developing nephric duct ...
[BlackBoxEvent:R-MMU-9830686] Expression of Pcdh19 in the nephric duct
[Summation:9831400] PAX2 binds upstream of the transcription start site of the P...
[BlackBoxEvent:R-MMU-9830432] Expression of Plac8 in the nephric duct
[RegulationReference:9831654] Positive gene expression regulation by 'Pax2:Plac8 gene [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
[Complex:R-MMU-9831439] Pax2:Plac8 gene [nucleoplasm]
[Summation:9831373] WFDC2 (also called HE4) is strongly expressed in the develop...
[BlackBoxEvent:R-MMU-9830419] Expression of Wfdc2 in the nephric duct
[RegulationReference:9830493] Positive gene expression regulation by 'Pax2 [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
[Summation:9831440] PAX2 is initially expressed in the intermediate mesoderm pri...
[Summation:9831393] GATA3 binds upstream of the LHX1 transcription start site (i...
[Reaction:R-MMU-9830476] Gata3 binds the Lhx1 gene
[Summation:9774262] Intermediate mesoderm gives rise to the urogenital system in...
[Reaction:R-MMU-9774518] Pax2 binds the Lhx1 gene
[Summation:9831409] Nephronectin (NPNT) is expressed in the ureteric bud epithel...
[BlackBoxEvent:R-MMU-9830685] Expression of Npnt in the nephric duct
[RegulationReference:9830680] Positive gene expression regulation by 'Lhx1:Npnt gene [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
[Summation:9831416] LHX1 (also called LIM1) binds three conserved sites near the...
[Reaction:R-MMU-9830659] Lhx1 binds the Npnt gene
[Complex:R-MMU-9830675] Lhx1:Npnt gene [nucleoplasm]
[RegulationReference:9830490] Positive gene expression regulation by 'Gata3:Pax2:Lhx1 gene [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
[RegulationReference:9774493] Positive gene expression regulation by 'Pax2:Lhx1 gene [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
[RegulationReference:9830464] Positive gene expression regulation by 'Pax8 [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
[Complex:R-MMU-9830496] Gata3:Pax2:Lhx1 gene [nucleoplasm]
[Complex:R-MMU-9774514] Pax2:Lhx1 gene [nucleoplasm]
[Reaction:R-MMU-9830467] Gata3 binds the Ret gene
[Complex:R-MMU-9830425] Gata3:Ret gene [nucleoplasm]
[Summation:9831385] Expression of GATA3 in the developing nephric duct is activa...
[BlackBoxEvent:R-MMU-9830438] Expression of Gata3 in the nephric duct
[RegulationReference:9830664] Positive gene expression regulation by 'Lhx1 [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis

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