Reactome | Expression of Gata3 in the nephric duct

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Expression of Gata3 in the nephric duct Show undefined attributes

authored	[InstanceEdit:9830487] May, Bruce, 2023-03-10
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9830452] May, Bruce, 2023-03-12
dbId	9830438
displayName	Expression of Gata3 in the nephric duct
edited	[InstanceEdit:9830487] May, Bruce, 2023-03-10
input	[EntityWithAccessionedSequence:R-MMU-9830509] Gata3 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9774516] A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis [LiteratureReference:9830412] Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney [LiteratureReference:9830431] Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice [LiteratureReference:9830483] Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction
maxDepth	1
modified	[InstanceEdit:9851767] May, Bruce, 2023-10-31
name	Expression of Gata3 in the nephric duct
orthologousEvent	[BlackBoxEvent:R-HSA-9830371] Expression of GATA3 in the nephric duct - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-9830515] Gata3 [nucleoplasm]
regulatedBy	[PositiveGeneExpressionRegulation:9830663] Positive gene expression regulation by 'Ctnnb1 [nucleoplasm]' [PositiveGeneExpressionRegulation:9792554] Positive gene expression regulation by 'Lhx1 [nucleoplasm]'
regulationReference	[RegulationReference:9830661] Positive gene expression regulation by 'Ctnnb1 [nucleoplasm]' Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction [RegulationReference:9830664] Positive gene expression regulation by 'Lhx1 [nucleoplasm]' A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9830438
summation	[Summation:9831433] Expression of Gata3 in the developing nephric duct is activa...