Reactome | Formation of the nephric duct

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Formation of the nephric duct Show undefined attributes

authored	[InstanceEdit:9830377] May, Bruce, 2023-03-08
created	[InstanceEdit:9830357] May, Bruce, 2023-03-09
dbId	9830364
displayName	Formation of the nephric duct
edited	[InstanceEdit:9830377] May, Bruce, 2023-03-08
eventOf	[Pathway:R-HSA-9830369] Kidney development - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:938346] nephric duct formation
hasDiagram	true
hasEHLD	false
hasEvent	[BlackBoxEvent:R-HSA-9761170] Expression of PAX2 in intermediate mesoderm - Homo sapiens [BlackBoxEvent:R-HSA-9761173] Expression of PAX8 in intermediate mesoderm - Homo sapiens [Reaction:R-HSA-9774496] PAX2 binds the LHX1 gene - Homo sapiens [BlackBoxEvent:R-HSA-9830356] Expression of LHX1 (LIM1) in the nephric duct - Homo sapiens [BlackBoxEvent:R-HSA-9830371] Expression of GATA3 in the nephric duct - Homo sapiens [Reaction:R-HSA-9830418] GATA3 binds the LHX1 gene - Homo sapiens [BlackBoxEvent:R-HSA-9830435] Expression of PAX2 in the nephric duct - Homo sapiens [Reaction:R-HSA-9830461] PAX2 binds the EMX2 gene - Homo sapiens [BlackBoxEvent:R-HSA-9830368] Expression of EMX2 in the nephric duct - Homo sapiens [BlackBoxEvent:R-HSA-9830376] Expression of MECOM (EVI1) in the nephric duct - Homo sapiens [BlackBoxEvent:R-HSA-9830372] Expression of ID4 in the nephric duct - Homo sapiens [Reaction:R-HSA-9831425] PAX2 binds the PLAC8 gene - Homo sapiens [BlackBoxEvent:R-HSA-9830362] Expression of PLAC8 in the nephric duct - Homo sapiens [BlackBoxEvent:R-HSA-9830365] Expression of WFDC2 in the nephric duct - Homo sapiens [BlackBoxEvent:R-HSA-9830373] Expression of PCDH19 in the nephric duct - Homo sapiens [Reaction:R-HSA-9830668] LHX1 binds the NPNT gene - Homo sapiens [BlackBoxEvent:R-HSA-9830475] Expression of NPNT in the nephric duct - Homo sapiens [Reaction:R-HSA-9830423] GATA3 binds the RET gene - Homo sapiens [BlackBoxEvent:R-HSA-9830480] Expression of RET in the nephric duct - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9792600] Gene regulatory network of renal primordium development [LiteratureReference:9830498] Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system [LiteratureReference:9830459] Mammalian kidney development: principles, progress, and projections [LiteratureReference:9831055] Cell and molecular biology of kidney development [LiteratureReference:9831588] Cellular and Molecular Mechanisms of Kidney Development: From the Embryo to the Kidney Organoid [LiteratureReference:9831370] Interplay between activin and Hox genes determines the formation of the kidney morphogenetic field [LiteratureReference:9774516] A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis [LiteratureReference:9830738] Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development [LiteratureReference:9830956] Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney
maxDepth	2
modified	[InstanceEdit:9851767] May, Bruce, 2023-10-31
name	Formation of the nephric duct
releaseDate	2023-12-06
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9830364
summation	[Summation:9831405] The nephric duct originates from nephrogenic cords of interm...

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[Pathway:R-HSA-9830369] Kidney development

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