canonical Wnt signaling pathway

accession 0060070
created [InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20
databaseName GO
dbId 259757
definition A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
displayName canonical Wnt signaling pathway
modified [InstanceEdit:9676538] Cook, Justin, 2020-02-17
name canonical Wnt signaling pathway
referenceDatabase [ReferenceDatabase:1] GO
schemaClass GO_BiologicalProcess
url https://www.ebi.ac.uk/QuickGO/term/GO:0060070
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