PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD

Stable Identifier
R-OCU-2161568
Type
Reaction [transition]
Species
Oryctolagus cuniculus
Compartment
cytosol
ReviewStatus
5/5
General
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PNG
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 | PPTX  | SBGN
PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD
In rabbits, 15-hydroxyprostaglandin dehydrogenase (HPGD) oxidises prostaglandins D2 (PGD2), E2 (PGE2), and F2alpha (PGF2a) to 15-keto-prostaglandin D2 (15k-PGD2), E2 (15k-PGE2), and F2alpha (15k-PGF2a) respectively (Bergholte & Okita 1986).
Literature References
PubMed ID Title Journal Year
3954355 Isolation and properties of lung 15-hydroxyprostaglandin dehydrogenase from pregnant rabbits

Bergholte, JM, Okita, RT

Arch Biochem Biophys 1986
Participants
Input
Output
Catalyst Activity

15-hydroxyprostaglandin dehydrogenase (NAD+) activity of HPGD dimer [cytosol]

Physical Entity
HPGD dimer [cytosol] (Oryctolagus cuniculus)
Activity
15-hydroxyprostaglandin dehydrogenase (NAD+) activity (GO:0016404)
Orthologous Events
PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD (Homo sapiens)
Authored
Williams, MG  (2012-02-24)
Reviewed
Rush, MG  (2012-11-10)
Created
Williams, MG  (2012-03-14)
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