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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
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Pathway Diagrams
Icon Info
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Citing us
Tools
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Analyse gene list
Analyse gene expression
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NADH [cytosol]
Stable Identifier
R-ALL-73473
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Drug ADME (Bos taurus)
Abacavir ADME (Bos taurus)
Abacavir metabolism (Bos taurus)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Bos taurus)
NADH [cytosol]
Azathioprine ADME (Bos taurus)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Bos taurus)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Bos taurus)
NADH [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Pyruvate metabolism (Bos taurus)
LDH tetramer oxidises LACT to PYR (Bos taurus)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Bos taurus)
NADH [cytosol]
Respiratory electron transport (Bos taurus)
Malate-aspartate shuttle (Bos taurus)
MDH1 reduces OA (Bos taurus)
NADH [cytosol]
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Ethanol oxidation (Bos taurus)
ADH5 oxidises S-HMGSH to S-FGSH (Bos taurus)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Bos taurus)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Bos taurus)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Bos taurus)
NADH [cytosol]
Phase II - Conjugation of compounds (Bos taurus)
Glucuronidation (Bos taurus)
Formation of the active cofactor, UDP-glucuronate (Bos taurus)
UDP-glucose is oxidised to UDP-glucuronate (Bos taurus)
NADH [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Carnitine synthesis (Bos taurus)
ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Bos taurus)
NADH [cytosol]
Phenylalanine and tyrosine metabolism (Bos taurus)
Phenylalanine metabolism (Bos taurus)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Bos taurus)
NADH [cytosol]
Serine biosynthesis (Bos taurus)
PHGDH tetramer dehydrogenates 3PG (Bos taurus)
NADH [cytosol]
Metabolism of carbohydrates (Bos taurus)
Formation of xylulose-5-phosphate (Bos taurus)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Bos taurus)
NADH [cytosol]
SORD tetramer oxidizes xylitol to D-xylulose (Bos taurus)
NADH [cytosol]
Fructose metabolism (Bos taurus)
Fructose biosynthesis (Bos taurus)
SORD oxidizes D-sorbitol to Fru (Bos taurus)
NADH [cytosol]
Fructose catabolism (Bos taurus)
ALDH1A1 oxidises GA to DGA (Bos taurus)
NADH [cytosol]
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
GAPDH tetramers reduce 1,3BPG to GA3P (Bos taurus)
NADH [cytosol]
Glycolysis (Bos taurus)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Bos taurus)
NADH [cytosol]
Metabolism of lipids (Bos taurus)
Biosynthesis of specialized proresolving mediators (SPMs) (Bos taurus)
Biosynthesis of DHA-derived SPMs (Bos taurus)
Biosynthesis of D-series resolvins (Bos taurus)
HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Bos taurus)
NADH [cytosol]
Biosynthesis of EPA-derived SPMs (Bos taurus)
Biosynthesis of E-series 18(S)-resolvins (Bos taurus)
HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Bos taurus)
NADH [cytosol]
Synthesis of Lipoxins (LX) (Bos taurus)
LXA4 is oxidised to 15k-LXA4 by HPGD (Bos taurus)
NADH [cytosol]
Ketone body metabolism (Bos taurus)
Synthesis of Ketone Bodies (Bos taurus)
BDH2 dehydrogenates 3HBA (Bos taurus)
NADH [cytosol]
Metabolism of steroids (Bos taurus)
Bile acid and bile salt metabolism (Bos taurus)
Synthesis of bile acids and bile salts (Bos taurus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Bos taurus)
Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Bos taurus)
NADH [cytosol]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Bos taurus)
Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Bos taurus)
NADH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Bos taurus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Bos taurus)
NADH [cytosol]
Cholesterol biosynthesis (Bos taurus)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Bos taurus)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Bos taurus)
NADH [cytosol]
Metabolism of steroid hormones (Bos taurus)
Androgen biosynthesis (Bos taurus)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Bos taurus)
NADH [cytosol]
Glucocorticoid biosynthesis (Bos taurus)
17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Bos taurus)
NADH [cytosol]
Mineralocorticoid biosynthesis (Bos taurus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Bos taurus)
NADH [cytosol]
Phospholipid metabolism (Bos taurus)
Glycerophospholipid biosynthesis (Bos taurus)
Synthesis of PA (Bos taurus)
DHAP is converted to G3P by GPD1/GPD1L (Bos taurus)
NADH [cytosol]
Sphingolipid metabolism (Bos taurus)
Sphingolipid catabolism (Bos taurus)
ALDH3A2-1 oxidises HD2NAL to PALM (Bos taurus)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Bos taurus)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Bos taurus)
NADH [cytosol]
Metabolism of nucleotides (Bos taurus)
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Bos taurus)
NADH [cytosol]
Nucleotide catabolism (Bos taurus)
Purine catabolism (Bos taurus)
XDH dehydrogenates hypoxanthine to form xanthine (Bos taurus)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Bos taurus)
NADH [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Bos taurus)
Cobalamin (Cbl) metabolism (Bos taurus)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Bos taurus)
NADH [cytosol]
Vitamin C (ascorbate) metabolism (Bos taurus)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Bos taurus)
NADH [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Bos taurus)
Hypusine synthesis from eIF5A-lysine (Bos taurus)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Bos taurus)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Bos taurus)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Bos taurus)
NADH [cytosol]
Sensory Perception (Bos taurus)
Visual phototransduction (Bos taurus)
The canonical retinoid cycle in rods (twilight vision) (Bos taurus)
RDH5 oxidises 11cROL to 11cRAL (Bos taurus)
NADH [cytosol]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
Signaling by Retinoic Acid (Bos taurus)
RA biosynthesis pathway (Bos taurus)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Bos taurus)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Bos taurus)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Bos taurus)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Bos taurus)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Bos taurus)
NADH [cytosol]
Transport of small molecules (Bos taurus)
O2/CO2 exchange in erythrocytes (Bos taurus)
Erythrocytes take up carbon dioxide and release oxygen (Bos taurus)
CYB5Rs reduce MetHb to HbA (Bos taurus)
NADH [cytosol]
Drug ADME (Caenorhabditis elegans)
Abacavir ADME (Caenorhabditis elegans)
Abacavir metabolism (Caenorhabditis elegans)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Caenorhabditis elegans)
NADH [cytosol]
Azathioprine ADME (Caenorhabditis elegans)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Caenorhabditis elegans)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Caenorhabditis elegans)
NADH [cytosol]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism (Caenorhabditis elegans)
LDH tetramer oxidises LACT to PYR (Caenorhabditis elegans)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Caenorhabditis elegans)
NADH [cytosol]
Respiratory electron transport (Caenorhabditis elegans)
Malate-aspartate shuttle (Caenorhabditis elegans)
MDH1 reduces OA (Caenorhabditis elegans)
NADH [cytosol]
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
Ethanol oxidation (Caenorhabditis elegans)
ADH5 oxidises S-HMGSH to S-FGSH (Caenorhabditis elegans)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Caenorhabditis elegans)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Caenorhabditis elegans)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Caenorhabditis elegans)
NADH [cytosol]
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Glucuronidation (Caenorhabditis elegans)
Formation of the active cofactor, UDP-glucuronate (Caenorhabditis elegans)
UDP-glucose is oxidised to UDP-glucuronate (Caenorhabditis elegans)
NADH [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Carnitine synthesis (Caenorhabditis elegans)
ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Caenorhabditis elegans)
NADH [cytosol]
Phenylalanine and tyrosine metabolism (Caenorhabditis elegans)
Phenylalanine metabolism (Caenorhabditis elegans)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Caenorhabditis elegans)
NADH [cytosol]
Serine biosynthesis (Caenorhabditis elegans)
PHGDH tetramer dehydrogenates 3PG (Caenorhabditis elegans)
NADH [cytosol]
Metabolism of carbohydrates (Caenorhabditis elegans)
Formation of xylulose-5-phosphate (Caenorhabditis elegans)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Caenorhabditis elegans)
NADH [cytosol]
SORD tetramer oxidizes xylitol to D-xylulose (Caenorhabditis elegans)
NADH [cytosol]
Fructose metabolism (Caenorhabditis elegans)
Fructose biosynthesis (Caenorhabditis elegans)
SORD oxidizes D-sorbitol to Fru (Caenorhabditis elegans)
NADH [cytosol]
Fructose catabolism (Caenorhabditis elegans)
ALDH1A1 oxidises GA to DGA (Caenorhabditis elegans)
NADH [cytosol]
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
GAPDH tetramers reduce 1,3BPG to GA3P (Caenorhabditis elegans)
NADH [cytosol]
Glycolysis (Caenorhabditis elegans)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Caenorhabditis elegans)
NADH [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Metabolism of steroids (Caenorhabditis elegans)
Cholesterol biosynthesis (Caenorhabditis elegans)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Caenorhabditis elegans)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Caenorhabditis elegans)
NADH [cytosol]
Phospholipid metabolism (Caenorhabditis elegans)
Glycerophospholipid biosynthesis (Caenorhabditis elegans)
Synthesis of PA (Caenorhabditis elegans)
DHAP is converted to G3P by GPD1/GPD1L (Caenorhabditis elegans)
NADH [cytosol]
Sphingolipid metabolism (Caenorhabditis elegans)
Sphingolipid catabolism (Caenorhabditis elegans)
ALDH3A2-1 oxidises HD2NAL to PALM (Caenorhabditis elegans)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Caenorhabditis elegans)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Caenorhabditis elegans)
NADH [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide biosynthesis (Caenorhabditis elegans)
Purine ribonucleoside monophosphate biosynthesis (Caenorhabditis elegans)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Caenorhabditis elegans)
NADH [cytosol]
Nucleotide catabolism (Caenorhabditis elegans)
Purine catabolism (Caenorhabditis elegans)
XDH dehydrogenates hypoxanthine to form xanthine (Caenorhabditis elegans)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Caenorhabditis elegans)
NADH [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Caenorhabditis elegans)
Cobalamin (Cbl) metabolism (Caenorhabditis elegans)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Caenorhabditis elegans)
NADH [cytosol]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Caenorhabditis elegans)
Hypusine synthesis from eIF5A-lysine (Caenorhabditis elegans)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Caenorhabditis elegans)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Caenorhabditis elegans)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Caenorhabditis elegans)
NADH [cytosol]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
Signaling by Retinoic Acid (Caenorhabditis elegans)
RA biosynthesis pathway (Caenorhabditis elegans)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Caenorhabditis elegans)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Caenorhabditis elegans)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Caenorhabditis elegans)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Caenorhabditis elegans)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Caenorhabditis elegans)
NADH [cytosol]
Drug ADME (Canis familiaris)
Abacavir ADME (Canis familiaris)
Abacavir metabolism (Canis familiaris)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Canis familiaris)
NADH [cytosol]
Azathioprine ADME (Canis familiaris)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Canis familiaris)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Canis familiaris)
NADH [cytosol]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Pyruvate metabolism (Canis familiaris)
LDH tetramer oxidises LACT to PYR (Canis familiaris)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Canis familiaris)
NADH [cytosol]
Respiratory electron transport (Canis familiaris)
Malate-aspartate shuttle (Canis familiaris)
MDH1 reduces OA (Canis familiaris)
NADH [cytosol]
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Ethanol oxidation (Canis familiaris)
ADH5 oxidises S-HMGSH to S-FGSH (Canis familiaris)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Canis familiaris)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Canis familiaris)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Canis familiaris)
NADH [cytosol]
Phase II - Conjugation of compounds (Canis familiaris)
Glucuronidation (Canis familiaris)
Formation of the active cofactor, UDP-glucuronate (Canis familiaris)
UDP-glucose is oxidised to UDP-glucuronate (Canis familiaris)
NADH [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Carnitine synthesis (Canis familiaris)
ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Canis familiaris)
NADH [cytosol]
Phenylalanine and tyrosine metabolism (Canis familiaris)
Phenylalanine metabolism (Canis familiaris)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Canis familiaris)
NADH [cytosol]
Serine biosynthesis (Canis familiaris)
PHGDH tetramer dehydrogenates 3PG (Canis familiaris)
NADH [cytosol]
Metabolism of carbohydrates (Canis familiaris)
Formation of xylulose-5-phosphate (Canis familiaris)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Canis familiaris)
NADH [cytosol]
SORD tetramer oxidizes xylitol to D-xylulose (Canis familiaris)
NADH [cytosol]
Fructose metabolism (Canis familiaris)
Fructose biosynthesis (Canis familiaris)
SORD oxidizes D-sorbitol to Fru (Canis familiaris)
NADH [cytosol]
Fructose catabolism (Canis familiaris)
ALDH1A1 oxidises GA to DGA (Canis familiaris)
NADH [cytosol]
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
GAPDH tetramers reduce 1,3BPG to GA3P (Canis familiaris)
NADH [cytosol]
Glycolysis (Canis familiaris)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Canis familiaris)
NADH [cytosol]
Metabolism of lipids (Canis familiaris)
Biosynthesis of specialized proresolving mediators (SPMs) (Canis familiaris)
Biosynthesis of DHA-derived SPMs (Canis familiaris)
Biosynthesis of D-series resolvins (Canis familiaris)
HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Canis familiaris)
NADH [cytosol]
Biosynthesis of EPA-derived SPMs (Canis familiaris)
Biosynthesis of E-series 18(S)-resolvins (Canis familiaris)
HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Canis familiaris)
NADH [cytosol]
Synthesis of Lipoxins (LX) (Canis familiaris)
LXA4 is oxidised to 15k-LXA4 by HPGD (Canis familiaris)
NADH [cytosol]
Ketone body metabolism (Canis familiaris)
Synthesis of Ketone Bodies (Canis familiaris)
BDH2 dehydrogenates 3HBA (Canis familiaris)
NADH [cytosol]
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Synthesis of bile acids and bile salts (Canis familiaris)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Canis familiaris)
Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Canis familiaris)
NADH [cytosol]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Canis familiaris)
Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Canis familiaris)
NADH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Canis familiaris)
NADH [cytosol]
Cholesterol biosynthesis (Canis familiaris)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Canis familiaris)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Canis familiaris)
NADH [cytosol]
Metabolism of steroid hormones (Canis familiaris)
Androgen biosynthesis (Canis familiaris)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Canis familiaris)
NADH [cytosol]
Glucocorticoid biosynthesis (Canis familiaris)
17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Canis familiaris)
NADH [cytosol]
Mineralocorticoid biosynthesis (Canis familiaris)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Canis familiaris)
NADH [cytosol]
Phospholipid metabolism (Canis familiaris)
Glycerophospholipid biosynthesis (Canis familiaris)
Synthesis of PA (Canis familiaris)
DHAP is converted to G3P by GPD1/GPD1L (Canis familiaris)
NADH [cytosol]
Sphingolipid metabolism (Canis familiaris)
Sphingolipid catabolism (Canis familiaris)
ALDH3A2-1 oxidises HD2NAL to PALM (Canis familiaris)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Canis familiaris)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Canis familiaris)
NADH [cytosol]
Metabolism of nucleotides (Canis familiaris)
Nucleotide biosynthesis (Canis familiaris)
Purine ribonucleoside monophosphate biosynthesis (Canis familiaris)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Canis familiaris)
NADH [cytosol]
Nucleotide catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
XDH dehydrogenates hypoxanthine to form xanthine (Canis familiaris)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Canis familiaris)
NADH [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Canis familiaris)
Cobalamin (Cbl) metabolism (Canis familiaris)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Canis familiaris)
NADH [cytosol]
Vitamin C (ascorbate) metabolism (Canis familiaris)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Canis familiaris)
NADH [cytosol]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Canis familiaris)
Hypusine synthesis from eIF5A-lysine (Canis familiaris)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Canis familiaris)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Canis familiaris)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Canis familiaris)
NADH [cytosol]
Sensory Perception (Canis familiaris)
Visual phototransduction (Canis familiaris)
The canonical retinoid cycle in rods (twilight vision) (Canis familiaris)
RDH5 oxidises 11cROL to 11cRAL (Canis familiaris)
NADH [cytosol]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
Signaling by Retinoic Acid (Canis familiaris)
RA biosynthesis pathway (Canis familiaris)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Canis familiaris)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Canis familiaris)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Canis familiaris)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Canis familiaris)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Canis familiaris)
NADH [cytosol]
Transport of small molecules (Canis familiaris)
O2/CO2 exchange in erythrocytes (Canis familiaris)
Erythrocytes take up carbon dioxide and release oxygen (Canis familiaris)
CYB5Rs reduce MetHb to HbA (Canis familiaris)
NADH [cytosol]
Drug ADME (Danio rerio)
Abacavir ADME (Danio rerio)
Abacavir metabolism (Danio rerio)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Danio rerio)
NADH [cytosol]
Azathioprine ADME (Danio rerio)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Danio rerio)
NADH [cytosol]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Pyruvate metabolism (Danio rerio)
LDH tetramer oxidises LACT to PYR (Danio rerio)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Danio rerio)
NADH [cytosol]
Respiratory electron transport (Danio rerio)
Malate-aspartate shuttle (Danio rerio)
MDH1 reduces OA (Danio rerio)
NADH [cytosol]
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
Ethanol oxidation (Danio rerio)
ADH5 oxidises S-HMGSH to S-FGSH (Danio rerio)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Danio rerio)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Danio rerio)
NADH [cytosol]
Phase II - Conjugation of compounds (Danio rerio)
Glucuronidation (Danio rerio)
Formation of the active cofactor, UDP-glucuronate (Danio rerio)
UDP-glucose is oxidised to UDP-glucuronate (Danio rerio)
NADH [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Carnitine synthesis (Danio rerio)
ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Danio rerio)
NADH [cytosol]
Phenylalanine and tyrosine metabolism (Danio rerio)
Phenylalanine metabolism (Danio rerio)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Danio rerio)
NADH [cytosol]
Metabolism of carbohydrates (Danio rerio)
Formation of xylulose-5-phosphate (Danio rerio)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Danio rerio)
NADH [cytosol]
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
GAPDH tetramers reduce 1,3BPG to GA3P (Danio rerio)
NADH [cytosol]
Glycolysis (Danio rerio)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Danio rerio)
NADH [cytosol]
Metabolism of lipids (Danio rerio)
Biosynthesis of specialized proresolving mediators (SPMs) (Danio rerio)
Biosynthesis of DHA-derived SPMs (Danio rerio)
Biosynthesis of D-series resolvins (Danio rerio)
HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Danio rerio)
NADH [cytosol]
Biosynthesis of EPA-derived SPMs (Danio rerio)
Biosynthesis of E-series 18(S)-resolvins (Danio rerio)
HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Danio rerio)
NADH [cytosol]
Synthesis of Lipoxins (LX) (Danio rerio)
LXA4 is oxidised to 15k-LXA4 by HPGD (Danio rerio)
NADH [cytosol]
Ketone body metabolism (Danio rerio)
Synthesis of Ketone Bodies (Danio rerio)
BDH2 dehydrogenates 3HBA (Danio rerio)
NADH [cytosol]
Metabolism of steroids (Danio rerio)
Bile acid and bile salt metabolism (Danio rerio)
Synthesis of bile acids and bile salts (Danio rerio)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Danio rerio)
Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Danio rerio)
NADH [cytosol]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Danio rerio)
Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Danio rerio)
NADH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Danio rerio)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Danio rerio)
NADH [cytosol]
Cholesterol biosynthesis (Danio rerio)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Danio rerio)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Danio rerio)
NADH [cytosol]
Metabolism of steroid hormones (Danio rerio)
Androgen biosynthesis (Danio rerio)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Danio rerio)
NADH [cytosol]
Glucocorticoid biosynthesis (Danio rerio)
17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Danio rerio)
NADH [cytosol]
Mineralocorticoid biosynthesis (Danio rerio)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Danio rerio)
NADH [cytosol]
Phospholipid metabolism (Danio rerio)
Glycerophospholipid biosynthesis (Danio rerio)
Synthesis of PA (Danio rerio)
DHAP is converted to G3P by GPD1/GPD1L (Danio rerio)
NADH [cytosol]
Sphingolipid metabolism (Danio rerio)
Sphingolipid catabolism (Danio rerio)
ALDH3A2-1 oxidises HD2NAL to PALM (Danio rerio)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Danio rerio)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Danio rerio)
NADH [cytosol]
Metabolism of nucleotides (Danio rerio)
Nucleotide biosynthesis (Danio rerio)
Purine ribonucleoside monophosphate biosynthesis (Danio rerio)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Danio rerio)
NADH [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Danio rerio)
Cobalamin (Cbl) metabolism (Danio rerio)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Danio rerio)
NADH [cytosol]
Vitamin C (ascorbate) metabolism (Danio rerio)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Danio rerio)
NADH [cytosol]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Danio rerio)
Hypusine synthesis from eIF5A-lysine (Danio rerio)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Danio rerio)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Danio rerio)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Danio rerio)
NADH [cytosol]
Sensory Perception (Danio rerio)
Visual phototransduction (Danio rerio)
The canonical retinoid cycle in rods (twilight vision) (Danio rerio)
RDH5 oxidises 11cROL to 11cRAL (Danio rerio)
NADH [cytosol]
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
Signaling by Retinoic Acid (Danio rerio)
RA biosynthesis pathway (Danio rerio)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Danio rerio)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Danio rerio)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Danio rerio)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Danio rerio)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Danio rerio)
NADH [cytosol]
Transport of small molecules (Danio rerio)
O2/CO2 exchange in erythrocytes (Danio rerio)
Erythrocytes take up carbon dioxide and release oxygen (Danio rerio)
CYB5Rs reduce MetHb to HbA (Danio rerio)
NADH [cytosol]
Drug ADME (Dictyostelium discoideum)
Abacavir ADME (Dictyostelium discoideum)
Abacavir metabolism (Dictyostelium discoideum)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Dictyostelium discoideum)
NADH [cytosol]
Azathioprine ADME (Dictyostelium discoideum)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Dictyostelium discoideum)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Dictyostelium discoideum)
NADH [cytosol]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Respiratory electron transport (Dictyostelium discoideum)
Malate-aspartate shuttle (Dictyostelium discoideum)
MDH1 reduces OA (Dictyostelium discoideum)
NADH [cytosol]
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Ethanol oxidation (Dictyostelium discoideum)
ADH5 oxidises S-HMGSH to S-FGSH (Dictyostelium discoideum)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Dictyostelium discoideum)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Dictyostelium discoideum)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Dictyostelium discoideum)
NADH [cytosol]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Phenylalanine and tyrosine metabolism (Dictyostelium discoideum)
Phenylalanine metabolism (Dictyostelium discoideum)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Dictyostelium discoideum)
NADH [cytosol]
Metabolism of carbohydrates (Dictyostelium discoideum)
Fructose metabolism (Dictyostelium discoideum)
Fructose catabolism (Dictyostelium discoideum)
ALDH1A1 oxidises GA to DGA (Dictyostelium discoideum)
NADH [cytosol]
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
GAPDH tetramers reduce 1,3BPG to GA3P (Dictyostelium discoideum)
NADH [cytosol]
Glycolysis (Dictyostelium discoideum)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Dictyostelium discoideum)
NADH [cytosol]
Metabolism of lipids (Dictyostelium discoideum)
Metabolism of steroids (Dictyostelium discoideum)
Cholesterol biosynthesis (Dictyostelium discoideum)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Dictyostelium discoideum)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Dictyostelium discoideum)
NADH [cytosol]
Sphingolipid metabolism (Dictyostelium discoideum)
Sphingolipid catabolism (Dictyostelium discoideum)
ALDH3A2-1 oxidises HD2NAL to PALM (Dictyostelium discoideum)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Dictyostelium discoideum)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Dictyostelium discoideum)
NADH [cytosol]
Metabolism of nucleotides (Dictyostelium discoideum)
Nucleotide biosynthesis (Dictyostelium discoideum)
Purine ribonucleoside monophosphate biosynthesis (Dictyostelium discoideum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Dictyostelium discoideum)
NADH [cytosol]
Nucleotide catabolism (Dictyostelium discoideum)
Purine catabolism (Dictyostelium discoideum)
XDH dehydrogenates hypoxanthine to form xanthine (Dictyostelium discoideum)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Dictyostelium discoideum)
NADH [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Dictyostelium discoideum)
Cobalamin (Cbl) metabolism (Dictyostelium discoideum)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Dictyostelium discoideum)
NADH [cytosol]
Vitamin C (ascorbate) metabolism (Dictyostelium discoideum)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Dictyostelium discoideum)
NADH [cytosol]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Dictyostelium discoideum)
Hypusine synthesis from eIF5A-lysine (Dictyostelium discoideum)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Dictyostelium discoideum)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Dictyostelium discoideum)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Dictyostelium discoideum)
NADH [cytosol]
Signal Transduction (Dictyostelium discoideum)
Signaling by Nuclear Receptors (Dictyostelium discoideum)
Signaling by Retinoic Acid (Dictyostelium discoideum)
RA biosynthesis pathway (Dictyostelium discoideum)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Dictyostelium discoideum)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Dictyostelium discoideum)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Dictyostelium discoideum)
NADH [cytosol]
Drug ADME (Drosophila melanogaster)
Abacavir ADME (Drosophila melanogaster)
Abacavir metabolism (Drosophila melanogaster)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Drosophila melanogaster)
NADH [cytosol]
Azathioprine ADME (Drosophila melanogaster)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Drosophila melanogaster)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Drosophila melanogaster)
NADH [cytosol]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
LDH tetramer oxidises LACT to PYR (Drosophila melanogaster)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Drosophila melanogaster)
NADH [cytosol]
Respiratory electron transport (Drosophila melanogaster)
Malate-aspartate shuttle (Drosophila melanogaster)
MDH1 reduces OA (Drosophila melanogaster)
NADH [cytosol]
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Ethanol oxidation (Drosophila melanogaster)
ADH5 oxidises S-HMGSH to S-FGSH (Drosophila melanogaster)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Drosophila melanogaster)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Drosophila melanogaster)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Drosophila melanogaster)
NADH [cytosol]
Phase II - Conjugation of compounds (Drosophila melanogaster)
Glucuronidation (Drosophila melanogaster)
Formation of the active cofactor, UDP-glucuronate (Drosophila melanogaster)
UDP-glucose is oxidised to UDP-glucuronate (Drosophila melanogaster)
NADH [cytosol]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Phenylalanine and tyrosine metabolism (Drosophila melanogaster)
Phenylalanine metabolism (Drosophila melanogaster)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Drosophila melanogaster)
NADH [cytosol]
Serine biosynthesis (Drosophila melanogaster)
PHGDH tetramer dehydrogenates 3PG (Drosophila melanogaster)
NADH [cytosol]
Metabolism of carbohydrates (Drosophila melanogaster)
Formation of xylulose-5-phosphate (Drosophila melanogaster)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Drosophila melanogaster)
NADH [cytosol]
SORD tetramer oxidizes xylitol to D-xylulose (Drosophila melanogaster)
NADH [cytosol]
Fructose metabolism (Drosophila melanogaster)
Fructose biosynthesis (Drosophila melanogaster)
SORD oxidizes D-sorbitol to Fru (Drosophila melanogaster)
NADH [cytosol]
Fructose catabolism (Drosophila melanogaster)
ALDH1A1 oxidises GA to DGA (Drosophila melanogaster)
NADH [cytosol]
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
GAPDH tetramers reduce 1,3BPG to GA3P (Drosophila melanogaster)
NADH [cytosol]
Glycolysis (Drosophila melanogaster)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Drosophila melanogaster)
NADH [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Biosynthesis of specialized proresolving mediators (SPMs) (Drosophila melanogaster)
Biosynthesis of DHA-derived SPMs (Drosophila melanogaster)
Biosynthesis of D-series resolvins (Drosophila melanogaster)
HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Drosophila melanogaster)
NADH [cytosol]
Biosynthesis of EPA-derived SPMs (Drosophila melanogaster)
Biosynthesis of E-series 18(S)-resolvins (Drosophila melanogaster)
HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Drosophila melanogaster)
NADH [cytosol]
Synthesis of Lipoxins (LX) (Drosophila melanogaster)
LXA4 is oxidised to 15k-LXA4 by HPGD (Drosophila melanogaster)
NADH [cytosol]
Phospholipid metabolism (Drosophila melanogaster)
Glycerophospholipid biosynthesis (Drosophila melanogaster)
Synthesis of PA (Drosophila melanogaster)
DHAP is converted to G3P by GPD1/GPD1L (Drosophila melanogaster)
NADH [cytosol]
Sphingolipid metabolism (Drosophila melanogaster)
Sphingolipid catabolism (Drosophila melanogaster)
ALDH3A2-1 oxidises HD2NAL to PALM (Drosophila melanogaster)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Drosophila melanogaster)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Drosophila melanogaster)
NADH [cytosol]
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide biosynthesis (Drosophila melanogaster)
Purine ribonucleoside monophosphate biosynthesis (Drosophila melanogaster)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Drosophila melanogaster)
NADH [cytosol]
Nucleotide catabolism (Drosophila melanogaster)
Purine catabolism (Drosophila melanogaster)
XDH dehydrogenates hypoxanthine to form xanthine (Drosophila melanogaster)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Drosophila melanogaster)
NADH [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Vitamin C (ascorbate) metabolism (Drosophila melanogaster)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Drosophila melanogaster)
NADH [cytosol]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Drosophila melanogaster)
Hypusine synthesis from eIF5A-lysine (Drosophila melanogaster)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Drosophila melanogaster)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Drosophila melanogaster)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Drosophila melanogaster)
NADH [cytosol]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
Signaling by Retinoic Acid (Drosophila melanogaster)
RA biosynthesis pathway (Drosophila melanogaster)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Drosophila melanogaster)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Drosophila melanogaster)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Drosophila melanogaster)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Drosophila melanogaster)
NADH [cytosol]
Drug ADME (Gallus gallus)
Abacavir ADME (Gallus gallus)
Abacavir metabolism (Gallus gallus)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Gallus gallus)
NADH [cytosol]
Azathioprine ADME (Gallus gallus)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Gallus gallus)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Gallus gallus)
NADH [cytosol]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Pyruvate metabolism (Gallus gallus)
LDH tetramer oxidises LACT to PYR (Gallus gallus)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Gallus gallus)
NADH [cytosol]
Respiratory electron transport (Gallus gallus)
Malate-aspartate shuttle (Gallus gallus)
MDH1 reduces OA (Gallus gallus)
NADH [cytosol]
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Ethanol oxidation (Gallus gallus)
ADH5 oxidises S-HMGSH to S-FGSH (Gallus gallus)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Gallus gallus)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Gallus gallus)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Gallus gallus)
NADH [cytosol]
Phase II - Conjugation of compounds (Gallus gallus)
Glucuronidation (Gallus gallus)
Formation of the active cofactor, UDP-glucuronate (Gallus gallus)
UDP-glucose is oxidised to UDP-glucuronate (Gallus gallus)
NADH [cytosol]
Metabolism of amino acids and derivatives (Gallus gallus)
Carnitine synthesis (Gallus gallus)
ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Gallus gallus)
NADH [cytosol]
Phenylalanine and tyrosine metabolism (Gallus gallus)
Phenylalanine metabolism (Gallus gallus)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Gallus gallus)
NADH [cytosol]
Metabolism of carbohydrates (Gallus gallus)
Formation of xylulose-5-phosphate (Gallus gallus)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Gallus gallus)
NADH [cytosol]
SORD tetramer oxidizes xylitol to D-xylulose (Gallus gallus)
NADH [cytosol]
Fructose metabolism (Gallus gallus)
Fructose biosynthesis (Gallus gallus)
SORD oxidizes D-sorbitol to Fru (Gallus gallus)
NADH [cytosol]
Fructose catabolism (Gallus gallus)
ALDH1A1 oxidises GA to DGA (Gallus gallus)
NADH [cytosol]
Glucose metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
GAPDH tetramers reduce 1,3BPG to GA3P (Gallus gallus)
NADH [cytosol]
Glycolysis (Gallus gallus)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Gallus gallus)
NADH [cytosol]
Metabolism of lipids (Gallus gallus)
Biosynthesis of specialized proresolving mediators (SPMs) (Gallus gallus)
Biosynthesis of DHA-derived SPMs (Gallus gallus)
Biosynthesis of D-series resolvins (Gallus gallus)
HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Gallus gallus)
NADH [cytosol]
Biosynthesis of EPA-derived SPMs (Gallus gallus)
Biosynthesis of E-series 18(S)-resolvins (Gallus gallus)
HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Gallus gallus)
NADH [cytosol]
Synthesis of Lipoxins (LX) (Gallus gallus)
LXA4 is oxidised to 15k-LXA4 by HPGD (Gallus gallus)
NADH [cytosol]
Ketone body metabolism (Gallus gallus)
Synthesis of Ketone Bodies (Gallus gallus)
BDH2 dehydrogenates 3HBA (Gallus gallus)
NADH [cytosol]
Metabolism of steroids (Gallus gallus)
Cholesterol biosynthesis (Gallus gallus)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Gallus gallus)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Gallus gallus)
NADH [cytosol]
Metabolism of steroid hormones (Gallus gallus)
Androgen biosynthesis (Gallus gallus)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Gallus gallus)
NADH [cytosol]
Glucocorticoid biosynthesis (Gallus gallus)
17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Gallus gallus)
NADH [cytosol]
Mineralocorticoid biosynthesis (Gallus gallus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Gallus gallus)
NADH [cytosol]
Phospholipid metabolism (Gallus gallus)
Glycerophospholipid biosynthesis (Gallus gallus)
Synthesis of PA (Gallus gallus)
DHAP is converted to G3P by GPD1/GPD1L (Gallus gallus)
NADH [cytosol]
Sphingolipid metabolism (Gallus gallus)
Sphingolipid catabolism (Gallus gallus)
ALDH3A2-1 oxidises HD2NAL to PALM (Gallus gallus)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Gallus gallus)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Gallus gallus)
NADH [cytosol]
Metabolism of nucleotides (Gallus gallus)
Nucleotide biosynthesis (Gallus gallus)
Purine ribonucleoside monophosphate biosynthesis (Gallus gallus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Gallus gallus)
NADH [cytosol]
Nucleotide catabolism (Gallus gallus)
Purine catabolism (Gallus gallus)
XDH dehydrogenates hypoxanthine to form xanthine (Gallus gallus)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Gallus gallus)
NADH [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Gallus gallus)
Cobalamin (Cbl) metabolism (Gallus gallus)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Gallus gallus)
NADH [cytosol]
Vitamin C (ascorbate) metabolism (Gallus gallus)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Gallus gallus)
NADH [cytosol]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Gallus gallus)
Hypusine synthesis from eIF5A-lysine (Gallus gallus)
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Gallus gallus)
NADH [cytosol]
Sensory Perception (Gallus gallus)
Visual phototransduction (Gallus gallus)
The canonical retinoid cycle in rods (twilight vision) (Gallus gallus)
RDH5 oxidises 11cROL to 11cRAL (Gallus gallus)
NADH [cytosol]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
Signaling by Retinoic Acid (Gallus gallus)
RA biosynthesis pathway (Gallus gallus)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Gallus gallus)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Gallus gallus)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Gallus gallus)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Gallus gallus)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Gallus gallus)
NADH [cytosol]
Transport of small molecules (Gallus gallus)
O2/CO2 exchange in erythrocytes (Gallus gallus)
Erythrocytes take up carbon dioxide and release oxygen (Gallus gallus)
CYB5Rs reduce MetHb to HbA (Gallus gallus)
NADH [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Latent infection - Other responses of Mtb to phagocytosis (Homo sapiens)
Cell redox homeostasis (Homo sapiens)
lpdC dimer reactivates dlaT (Homo sapiens)
NADH [cytosol]
Tolerance by Mtb to nitric oxide produced by macrophages (Homo sapiens)
MscR reduces nitrosomycothiol to ammonia (Homo sapiens)
NADH [cytosol]
Drug ADME (Homo sapiens)
Abacavir ADME (Homo sapiens)
Abacavir metabolism (Homo sapiens)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Homo sapiens)
NADH [cytosol]
Azathioprine ADME (Homo sapiens)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Homo sapiens)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Homo sapiens)
NADH [cytosol]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Pyruvate metabolism (Homo sapiens)
LDH tetramer oxidises LACT to PYR (Homo sapiens)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Homo sapiens)
NADH [cytosol]
Respiratory electron transport (Homo sapiens)
Malate-aspartate shuttle (Homo sapiens)
MDH1 reduces OA (Homo sapiens)
NADH [cytosol]
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Ethanol oxidation (Homo sapiens)
ADH5 oxidises S-HMGSH to S-FGSH (Homo sapiens)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Homo sapiens)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Homo sapiens)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Homo sapiens)
NADH [cytosol]
Phase II - Conjugation of compounds (Homo sapiens)
Glucuronidation (Homo sapiens)
Formation of the active cofactor, UDP-glucuronate (Homo sapiens)
UDP-glucose is oxidised to UDP-glucuronate (Homo sapiens)
NADH [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Carnitine synthesis (Homo sapiens)
ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Homo sapiens)
NADH [cytosol]
Phenylalanine and tyrosine metabolism (Homo sapiens)
Phenylalanine metabolism (Homo sapiens)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Homo sapiens)
NADH [cytosol]
Serine biosynthesis (Homo sapiens)
PHGDH tetramer dehydrogenates 3PG (Homo sapiens)
NADH [cytosol]
Tryptophan catabolism (Homo sapiens)
2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ (Homo sapiens)
NADH [cytosol]
Metabolism of carbohydrates (Homo sapiens)
Formation of xylulose-5-phosphate (Homo sapiens)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Homo sapiens)
NADH [cytosol]
SORD tetramer oxidizes xylitol to D-xylulose (Homo sapiens)
NADH [cytosol]
Fructose metabolism (Homo sapiens)
Fructose biosynthesis (Homo sapiens)
SORD oxidizes D-sorbitol to Fru (Homo sapiens)
NADH [cytosol]
Fructose catabolism (Homo sapiens)
ALDH1A1 oxidises GA to DGA (Homo sapiens)
NADH [cytosol]
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
GAPDH tetramers reduce 1,3BPG to GA3P (Homo sapiens)
NADH [cytosol]
Glycolysis (Homo sapiens)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Homo sapiens)
NADH [cytosol]
Metabolism of lipids (Homo sapiens)
Biosynthesis of specialized proresolving mediators (SPMs) (Homo sapiens)
Biosynthesis of DHA-derived SPMs (Homo sapiens)
Biosynthesis of D-series resolvins (Homo sapiens)
HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Homo sapiens)
NADH [cytosol]
Biosynthesis of EPA-derived SPMs (Homo sapiens)
Biosynthesis of E-series 18(S)-resolvins (Homo sapiens)
HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Homo sapiens)
NADH [cytosol]
Synthesis of Lipoxins (LX) (Homo sapiens)
LXA4 is oxidised to 15k-LXA4 by HPGD (Homo sapiens)
NADH [cytosol]
Fatty acid metabolism (Homo sapiens)
Arachidonic acid metabolism (Homo sapiens)
Synthesis of 15-eicosatetraenoic acid derivatives (Homo sapiens)
15S-HETE is oxidised to 15-oxoETE by 15-HEDH (Homo sapiens)
NAD(P)H [cytosol]
NADH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)
PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD (Homo sapiens)
NADH [cytosol]
Ketone body metabolism (Homo sapiens)
Synthesis of Ketone Bodies (Homo sapiens)
BDH2 dehydrogenates 3HBA (Homo sapiens)
NADH [cytosol]
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Synthesis of bile acids and bile salts (Homo sapiens)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Homo sapiens)
Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Homo sapiens)
NADH [cytosol]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Homo sapiens)
Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Homo sapiens)
NADH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Homo sapiens)
NADH [cytosol]
Cholesterol biosynthesis (Homo sapiens)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Homo sapiens)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Homo sapiens)
NADH [cytosol]
Metabolism of steroid hormones (Homo sapiens)
Androgen biosynthesis (Homo sapiens)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Homo sapiens)
NADH [cytosol]
Glucocorticoid biosynthesis (Homo sapiens)
17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Homo sapiens)
NADH [cytosol]
Mineralocorticoid biosynthesis (Homo sapiens)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Homo sapiens)
NADH [cytosol]
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Synthesis of PA (Homo sapiens)
DHAP is converted to G3P by GPD1/GPD1L (Homo sapiens)
NADH [cytosol]
Sphingolipid metabolism (Homo sapiens)
Sphingolipid catabolism (Homo sapiens)
ALDH3A2-1 oxidises HD2NAL to PALM (Homo sapiens)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Homo sapiens)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Homo sapiens)
NADH [cytosol]
Metabolism of nucleotides (Homo sapiens)
Nucleotide biosynthesis (Homo sapiens)
Purine ribonucleoside monophosphate biosynthesis (Homo sapiens)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Homo sapiens)
NADH [cytosol]
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
XDH dehydrogenates hypoxanthine to form xanthine (Homo sapiens)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Homo sapiens)
NADH [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of fat-soluble vitamins (Homo sapiens)
Retinoid metabolism and transport (Homo sapiens)
RETSAT reduces atROL to at-13,14-dhROL (Homo sapiens)
NADH [cytosol]
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
Cobalamin (Cbl) metabolism (Homo sapiens)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Homo sapiens)
NADH [cytosol]
Vitamin C (ascorbate) metabolism (Homo sapiens)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Homo sapiens)
NADH [cytosol]
Metabolism of RNA (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA modification in the nucleus and cytosol (Homo sapiens)
DUS2:EPRS reduces uridine to dihydrouridine in tRNAs (Homo sapiens)
NAD(P)H [cytosol]
NADH [cytosol]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Hypusine synthesis from eIF5A-lysine (Homo sapiens)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Homo sapiens)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Homo sapiens)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Homo sapiens)
NADH [cytosol]
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
Retinoid metabolism and transport (Homo sapiens)
RETSAT reduces atROL to at-13,14-dhROL (Homo sapiens)
NADH [cytosol]
The canonical retinoid cycle in rods (twilight vision) (Homo sapiens)
RDH5 oxidises 11cROL to 11cRAL (Homo sapiens)
NADH [cytosol]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
RA biosynthesis pathway (Homo sapiens)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Homo sapiens)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Homo sapiens)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Homo sapiens)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Homo sapiens)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Homo sapiens)
NADH [cytosol]
Transport of small molecules (Homo sapiens)
O2/CO2 exchange in erythrocytes (Homo sapiens)
Erythrocytes take up carbon dioxide and release oxygen (Homo sapiens)
CYB5Rs reduce MetHb to HbA (Homo sapiens)
NADH [cytosol]
Drug ADME (Mus musculus)
Abacavir ADME (Mus musculus)
Abacavir metabolism (Mus musculus)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Mus musculus)
NADH [cytosol]
Azathioprine ADME (Mus musculus)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Mus musculus)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Mus musculus)
NADH [cytosol]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Pyruvate metabolism (Mus musculus)
LDH tetramer oxidises LACT to PYR (Mus musculus)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Mus musculus)
NADH [cytosol]
Respiratory electron transport (Mus musculus)
Malate-aspartate shuttle (Mus musculus)
MDH1 reduces OA (Mus musculus)
NADH [cytosol]
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Ethanol oxidation (Mus musculus)
ADH5 oxidises S-HMGSH to S-FGSH (Mus musculus)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Mus musculus)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Mus musculus)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Mus musculus)
NADH [cytosol]
Phase II - Conjugation of compounds (Mus musculus)
Glucuronidation (Mus musculus)
Formation of the active cofactor, UDP-glucuronate (Mus musculus)
UDP-glucose is oxidised to UDP-glucuronate (Mus musculus)
NADH [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Carnitine synthesis (Mus musculus)
ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Mus musculus)
NADH [cytosol]
Phenylalanine and tyrosine metabolism (Mus musculus)
Phenylalanine metabolism (Mus musculus)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Mus musculus)
NADH [cytosol]
Serine biosynthesis (Mus musculus)
PHGDH tetramer dehydrogenates 3PG (Mus musculus)
NADH [cytosol]
Metabolism of carbohydrates (Mus musculus)
Formation of xylulose-5-phosphate (Mus musculus)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Mus musculus)
NADH [cytosol]
SORD tetramer oxidizes xylitol to D-xylulose (Mus musculus)
NADH [cytosol]
Fructose metabolism (Mus musculus)
Fructose biosynthesis (Mus musculus)
SORD oxidizes D-sorbitol to Fru (Mus musculus)
NADH [cytosol]
Fructose catabolism (Mus musculus)
ALDH1A1 oxidises GA to DGA (Mus musculus)
NADH [cytosol]
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
GAPDH tetramers reduce 1,3BPG to GA3P (Mus musculus)
NADH [cytosol]
Glycolysis (Mus musculus)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Mus musculus)
NADH [cytosol]
Metabolism of lipids (Mus musculus)
Biosynthesis of specialized proresolving mediators (SPMs) (Mus musculus)
Biosynthesis of DHA-derived SPMs (Mus musculus)
Biosynthesis of D-series resolvins (Mus musculus)
HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Mus musculus)
NADH [cytosol]
Biosynthesis of EPA-derived SPMs (Mus musculus)
Biosynthesis of E-series 18(S)-resolvins (Mus musculus)
HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Mus musculus)
NADH [cytosol]
Synthesis of Lipoxins (LX) (Mus musculus)
LXA4 is oxidised to 15k-LXA4 by HPGD (Mus musculus)
NADH [cytosol]
Ketone body metabolism (Mus musculus)
Synthesis of Ketone Bodies (Mus musculus)
BDH2 dehydrogenates 3HBA (Mus musculus)
NADH [cytosol]
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Synthesis of bile acids and bile salts (Mus musculus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Mus musculus)
Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Mus musculus)
NADH [cytosol]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Mus musculus)
Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Mus musculus)
NADH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Mus musculus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Mus musculus)
NADH [cytosol]
Cholesterol biosynthesis (Mus musculus)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Mus musculus)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Mus musculus)
NADH [cytosol]
Metabolism of steroid hormones (Mus musculus)
Androgen biosynthesis (Mus musculus)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Mus musculus)
NADH [cytosol]
Glucocorticoid biosynthesis (Mus musculus)
17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Mus musculus)
NADH [cytosol]
Mineralocorticoid biosynthesis (Mus musculus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Mus musculus)
NADH [cytosol]
Phospholipid metabolism (Mus musculus)
Glycerophospholipid biosynthesis (Mus musculus)
Synthesis of PA (Mus musculus)
DHAP is converted to G3P by GPD1/GPD1L (Mus musculus)
NADH [cytosol]
Sphingolipid metabolism (Mus musculus)
Sphingolipid catabolism (Mus musculus)
ALDH3A2-1 oxidises HD2NAL to PALM (Mus musculus)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Mus musculus)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Mus musculus)
NADH [cytosol]
Metabolism of nucleotides (Mus musculus)
Nucleotide biosynthesis (Mus musculus)
Purine ribonucleoside monophosphate biosynthesis (Mus musculus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Mus musculus)
NADH [cytosol]
Nucleotide catabolism (Mus musculus)
Purine catabolism (Mus musculus)
XDH dehydrogenates hypoxanthine to form xanthine (Mus musculus)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Mus musculus)
NADH [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Mus musculus)
Cobalamin (Cbl) metabolism (Mus musculus)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Mus musculus)
NADH [cytosol]
Vitamin C (ascorbate) metabolism (Mus musculus)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Mus musculus)
NADH [cytosol]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Mus musculus)
Hypusine synthesis from eIF5A-lysine (Mus musculus)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Mus musculus)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Mus musculus)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Mus musculus)
NADH [cytosol]
Sensory Perception (Mus musculus)
Visual phototransduction (Mus musculus)
The canonical retinoid cycle in rods (twilight vision) (Mus musculus)
RDH5 oxidises 11cROL to 11cRAL (Mus musculus)
NADH [cytosol]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
Signaling by Retinoic Acid (Mus musculus)
RA biosynthesis pathway (Mus musculus)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Mus musculus)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Mus musculus)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Mus musculus)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Mus musculus)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Mus musculus)
NADH [cytosol]
Transport of small molecules (Mus musculus)
O2/CO2 exchange in erythrocytes (Mus musculus)
Erythrocytes take up carbon dioxide and release oxygen (Mus musculus)
CYB5Rs reduce MetHb to HbA (Mus musculus)
NADH [cytosol]
Mycobacterium tuberculosis biological processes (Mycobacterium tuberculosis)
Chorismate via Shikimate Pathway (Mycobacterium tuberculosis)
DHQ from DAHP dephosphorylation (Mycobacterium tuberculosis)
NADH [cytosol]
Mycothiol metabolism (Mycobacterium tuberculosis)
Mycothiol-dependent detoxification (Mycobacterium tuberculosis)
mycothiol binds formaldehyde and is dehydrogenated (Mycobacterium tuberculosis)
NADH [cytosol]
Drug ADME (Plasmodium falciparum)
Azathioprine ADME (Plasmodium falciparum)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Plasmodium falciparum)
NADH [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of carbohydrates (Plasmodium falciparum)
Glucose metabolism (Plasmodium falciparum)
Gluconeogenesis (Plasmodium falciparum)
GAPDH tetramers reduce 1,3BPG to GA3P (Plasmodium falciparum)
NADH [cytosol]
Glycolysis (Plasmodium falciparum)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Plasmodium falciparum)
NADH [cytosol]
Metabolism of lipids (Plasmodium falciparum)
Phospholipid metabolism (Plasmodium falciparum)
Glycerophospholipid biosynthesis (Plasmodium falciparum)
Synthesis of PA (Plasmodium falciparum)
DHAP is converted to G3P by GPD1/GPD1L (Plasmodium falciparum)
NADH [cytosol]
Metabolism of nucleotides (Plasmodium falciparum)
Nucleotide biosynthesis (Plasmodium falciparum)
Purine ribonucleoside monophosphate biosynthesis (Plasmodium falciparum)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Plasmodium falciparum)
NADH [cytosol]
Metabolism of proteins (Plasmodium falciparum)
Post-translational protein modification (Plasmodium falciparum)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Plasmodium falciparum)
Hypusine synthesis from eIF5A-lysine (Plasmodium falciparum)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Plasmodium falciparum)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Plasmodium falciparum)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Plasmodium falciparum)
NADH [cytosol]
Drug ADME (Rattus norvegicus)
Abacavir ADME (Rattus norvegicus)
Abacavir metabolism (Rattus norvegicus)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Rattus norvegicus)
NADH [cytosol]
Azathioprine ADME (Rattus norvegicus)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Rattus norvegicus)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Rattus norvegicus)
NADH [cytosol]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism (Rattus norvegicus)
LDH tetramer oxidises LACT to PYR (Rattus norvegicus)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Rattus norvegicus)
NADH [cytosol]
Respiratory electron transport (Rattus norvegicus)
Malate-aspartate shuttle (Rattus norvegicus)
MDH1 reduces OA (Rattus norvegicus)
NADH [cytosol]
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Ethanol oxidation (Rattus norvegicus)
ADH5 oxidises S-HMGSH to S-FGSH (Rattus norvegicus)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Rattus norvegicus)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Rattus norvegicus)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Rattus norvegicus)
NADH [cytosol]
Phase II - Conjugation of compounds (Rattus norvegicus)
Glucuronidation (Rattus norvegicus)
Formation of the active cofactor, UDP-glucuronate (Rattus norvegicus)
UDP-glucose is oxidised to UDP-glucuronate (Rattus norvegicus)
NADH [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Carnitine synthesis (Rattus norvegicus)
ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Rattus norvegicus)
NADH [cytosol]
Phenylalanine and tyrosine metabolism (Rattus norvegicus)
Phenylalanine metabolism (Rattus norvegicus)
q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Rattus norvegicus)
NADH [cytosol]
Serine biosynthesis (Rattus norvegicus)
PHGDH tetramer dehydrogenates 3PG (Rattus norvegicus)
NADH [cytosol]
Metabolism of carbohydrates (Rattus norvegicus)
Formation of xylulose-5-phosphate (Rattus norvegicus)
CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Rattus norvegicus)
NADH [cytosol]
SORD tetramer oxidizes xylitol to D-xylulose (Rattus norvegicus)
NADH [cytosol]
Fructose metabolism (Rattus norvegicus)
Fructose biosynthesis (Rattus norvegicus)
SORD oxidizes D-sorbitol to Fru (Rattus norvegicus)
NADH [cytosol]
Fructose catabolism (Rattus norvegicus)
ALDH1A1 oxidises GA to DGA (Rattus norvegicus)
NADH [cytosol]
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
GAPDH tetramers reduce 1,3BPG to GA3P (Rattus norvegicus)
NADH [cytosol]
Glycolysis (Rattus norvegicus)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Rattus norvegicus)
NADH [cytosol]
Metabolism of lipids (Rattus norvegicus)
Biosynthesis of specialized proresolving mediators (SPMs) (Rattus norvegicus)
Biosynthesis of DHA-derived SPMs (Rattus norvegicus)
Biosynthesis of D-series resolvins (Rattus norvegicus)
HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Rattus norvegicus)
NADH [cytosol]
Biosynthesis of EPA-derived SPMs (Rattus norvegicus)
Biosynthesis of E-series 18(S)-resolvins (Rattus norvegicus)
HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Rattus norvegicus)
NADH [cytosol]
Synthesis of Lipoxins (LX) (Rattus norvegicus)
LXA4 is oxidised to 15k-LXA4 by HPGD (Rattus norvegicus)
NADH [cytosol]
Ketone body metabolism (Rattus norvegicus)
Synthesis of Ketone Bodies (Rattus norvegicus)
BDH2 dehydrogenates 3HBA (Rattus norvegicus)
NADH [cytosol]
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Rattus norvegicus)
Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Rattus norvegicus)
NADH [cytosol]
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Rattus norvegicus)
Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Rattus norvegicus)
NADH [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Rattus norvegicus)
NADH [cytosol]
Cholesterol biosynthesis (Rattus norvegicus)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Rattus norvegicus)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Rattus norvegicus)
NADH [cytosol]
Metabolism of steroid hormones (Rattus norvegicus)
Androgen biosynthesis (Rattus norvegicus)
HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Rattus norvegicus)
NADH [cytosol]
Glucocorticoid biosynthesis (Rattus norvegicus)
17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Rattus norvegicus)
NADH [cytosol]
Mineralocorticoid biosynthesis (Rattus norvegicus)
Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Rattus norvegicus)
NADH [cytosol]
Phospholipid metabolism (Rattus norvegicus)
Glycerophospholipid biosynthesis (Rattus norvegicus)
Synthesis of PA (Rattus norvegicus)
DHAP is converted to G3P by GPD1/GPD1L (Rattus norvegicus)
NADH [cytosol]
Sphingolipid metabolism (Rattus norvegicus)
Sphingolipid catabolism (Rattus norvegicus)
ALDH3A2-1 oxidises HD2NAL to PALM (Rattus norvegicus)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Rattus norvegicus)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Rattus norvegicus)
NADH [cytosol]
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide biosynthesis (Rattus norvegicus)
Purine ribonucleoside monophosphate biosynthesis (Rattus norvegicus)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Rattus norvegicus)
NADH [cytosol]
Nucleotide catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
XDH dehydrogenates hypoxanthine to form xanthine (Rattus norvegicus)
NADH [cytosol]
XDH dehydrogenates xanthine to form urate (Rattus norvegicus)
NADH [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Rattus norvegicus)
Cobalamin (Cbl) metabolism (Rattus norvegicus)
Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Rattus norvegicus)
NADH [cytosol]
Vitamin C (ascorbate) metabolism (Rattus norvegicus)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Rattus norvegicus)
NADH [cytosol]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Rattus norvegicus)
Hypusine synthesis from eIF5A-lysine (Rattus norvegicus)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Rattus norvegicus)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Rattus norvegicus)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Rattus norvegicus)
NADH [cytosol]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
RA biosynthesis pathway (Rattus norvegicus)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Rattus norvegicus)
NADH [cytosol]
ALDH8A1 oxidises 9cRAL to 9cRA (Rattus norvegicus)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Rattus norvegicus)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Rattus norvegicus)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Rattus norvegicus)
NADH [cytosol]
Transport of small molecules (Rattus norvegicus)
O2/CO2 exchange in erythrocytes (Rattus norvegicus)
Erythrocytes take up carbon dioxide and release oxygen (Rattus norvegicus)
CYB5Rs reduce MetHb to HbA (Rattus norvegicus)
NADH [cytosol]
Drug ADME (Saccharomyces cerevisiae)
Abacavir ADME (Saccharomyces cerevisiae)
Abacavir metabolism (Saccharomyces cerevisiae)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Saccharomyces cerevisiae)
NADH [cytosol]
Azathioprine ADME (Saccharomyces cerevisiae)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Saccharomyces cerevisiae)
NADH [cytosol]
Metabolism (Saccharomyces cerevisiae)
Biological oxidations (Saccharomyces cerevisiae)
Phase I - Functionalization of compounds (Saccharomyces cerevisiae)
Ethanol oxidation (Saccharomyces cerevisiae)
ADH5 oxidises S-HMGSH to S-FGSH (Saccharomyces cerevisiae)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Saccharomyces cerevisiae)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Saccharomyces cerevisiae)
NADH [cytosol]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Formation of xylulose-5-phosphate (Saccharomyces cerevisiae)
SORD tetramer oxidizes xylitol to D-xylulose (Saccharomyces cerevisiae)
NADH [cytosol]
Fructose metabolism (Saccharomyces cerevisiae)
Fructose biosynthesis (Saccharomyces cerevisiae)
SORD oxidizes D-sorbitol to Fru (Saccharomyces cerevisiae)
NADH [cytosol]
Fructose catabolism (Saccharomyces cerevisiae)
ALDH1A1 oxidises GA to DGA (Saccharomyces cerevisiae)
NADH [cytosol]
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
GAPDH tetramers reduce 1,3BPG to GA3P (Saccharomyces cerevisiae)
NADH [cytosol]
Glycolysis (Saccharomyces cerevisiae)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Saccharomyces cerevisiae)
NADH [cytosol]
Metabolism of lipids (Saccharomyces cerevisiae)
Metabolism of steroids (Saccharomyces cerevisiae)
Cholesterol biosynthesis (Saccharomyces cerevisiae)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Saccharomyces cerevisiae)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Saccharomyces cerevisiae)
NADH [cytosol]
Phospholipid metabolism (Saccharomyces cerevisiae)
Glycerophospholipid biosynthesis (Saccharomyces cerevisiae)
Synthesis of PA (Saccharomyces cerevisiae)
DHAP is converted to G3P by GPD1/GPD1L (Saccharomyces cerevisiae)
NADH [cytosol]
Sphingolipid metabolism (Saccharomyces cerevisiae)
Sphingolipid catabolism (Saccharomyces cerevisiae)
ALDH3A2-1 oxidises HD2NAL to PALM (Saccharomyces cerevisiae)
NADH [cytosol]
ALDH3B1 oxidises HXAL to PALM (Saccharomyces cerevisiae)
NADH [cytosol]
ALDH3B2 oxidises HXAL to PALM (Saccharomyces cerevisiae)
NADH [cytosol]
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide biosynthesis (Saccharomyces cerevisiae)
Purine ribonucleoside monophosphate biosynthesis (Saccharomyces cerevisiae)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Saccharomyces cerevisiae)
NADH [cytosol]
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of water-soluble vitamins and cofactors (Saccharomyces cerevisiae)
Vitamin C (ascorbate) metabolism (Saccharomyces cerevisiae)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Saccharomyces cerevisiae)
NADH [cytosol]
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Saccharomyces cerevisiae)
Hypusine synthesis from eIF5A-lysine (Saccharomyces cerevisiae)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Saccharomyces cerevisiae)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Saccharomyces cerevisiae)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Saccharomyces cerevisiae)
NADH [cytosol]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
Signaling by Retinoic Acid (Saccharomyces cerevisiae)
RA biosynthesis pathway (Saccharomyces cerevisiae)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Saccharomyces cerevisiae)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Saccharomyces cerevisiae)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Saccharomyces cerevisiae)
NADH [cytosol]
Drug ADME (Schizosaccharomyces pombe)
Abacavir ADME (Schizosaccharomyces pombe)
Abacavir metabolism (Schizosaccharomyces pombe)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Schizosaccharomyces pombe)
NADH [cytosol]
Azathioprine ADME (Schizosaccharomyces pombe)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Schizosaccharomyces pombe)
NADH [cytosol]
Metabolism (Schizosaccharomyces pombe)
Biological oxidations (Schizosaccharomyces pombe)
Phase I - Functionalization of compounds (Schizosaccharomyces pombe)
Ethanol oxidation (Schizosaccharomyces pombe)
ADH5 oxidises S-HMGSH to S-FGSH (Schizosaccharomyces pombe)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Schizosaccharomyces pombe)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Schizosaccharomyces pombe)
NADH [cytosol]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Formation of xylulose-5-phosphate (Schizosaccharomyces pombe)
SORD tetramer oxidizes xylitol to D-xylulose (Schizosaccharomyces pombe)
NADH [cytosol]
Fructose metabolism (Schizosaccharomyces pombe)
Fructose biosynthesis (Schizosaccharomyces pombe)
SORD oxidizes D-sorbitol to Fru (Schizosaccharomyces pombe)
NADH [cytosol]
Fructose catabolism (Schizosaccharomyces pombe)
ALDH1A1 oxidises GA to DGA (Schizosaccharomyces pombe)
NADH [cytosol]
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
GAPDH tetramers reduce 1,3BPG to GA3P (Schizosaccharomyces pombe)
NADH [cytosol]
Glycolysis (Schizosaccharomyces pombe)
D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Schizosaccharomyces pombe)
NADH [cytosol]
Metabolism of lipids (Schizosaccharomyces pombe)
Metabolism of steroids (Schizosaccharomyces pombe)
Cholesterol biosynthesis (Schizosaccharomyces pombe)
4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Schizosaccharomyces pombe)
NADH [cytosol]
4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Schizosaccharomyces pombe)
NADH [cytosol]
Phospholipid metabolism (Schizosaccharomyces pombe)
Glycerophospholipid biosynthesis (Schizosaccharomyces pombe)
Synthesis of PA (Schizosaccharomyces pombe)
DHAP is converted to G3P by GPD1/GPD1L (Schizosaccharomyces pombe)
NADH [cytosol]
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide biosynthesis (Schizosaccharomyces pombe)
Purine ribonucleoside monophosphate biosynthesis (Schizosaccharomyces pombe)
IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Schizosaccharomyces pombe)
NADH [cytosol]
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Vitamin C (ascorbate) metabolism (Schizosaccharomyces pombe)
CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Schizosaccharomyces pombe)
NADH [cytosol]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Schizosaccharomyces pombe)
Hypusine synthesis from eIF5A-lysine (Schizosaccharomyces pombe)
DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Schizosaccharomyces pombe)
NADH [cytosol]
DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Schizosaccharomyces pombe)
NADH [cytosol]
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Schizosaccharomyces pombe)
NADH [cytosol]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
Signaling by Retinoic Acid (Schizosaccharomyces pombe)
RA biosynthesis pathway (Schizosaccharomyces pombe)
ADH1A,1C,4 oxidise atROL to atRAL in vitro (Schizosaccharomyces pombe)
NADH [cytosol]
ALDHs oxidise atRAL to atRA (Schizosaccharomyces pombe)
NADH [cytosol]
RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Schizosaccharomyces pombe)
NADH [cytosol]
RDH5,RDH11 oxidise 11cROL to 11cRAL (Schizosaccharomyces pombe)
NADH [cytosol]
Drug ADME (Sus scrofa)
Abacavir ADME (Sus scrofa)
Abacavir metabolism (Sus scrofa)
abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Sus scrofa)
NADH [cytosol]
Azathioprine ADME (Sus scrofa)
IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Sus scrofa)
NADH [cytosol]
XDH oxidises 6MP to 6TU (Sus scrofa)
NADH [cytosol]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
LDH tetramer oxidises LACT to PYR (Sus scrofa)
NADH [cytosol]
LDH tetramer reduces PYR to LACT (Sus scrofa)
NADH [cytosol]
Respiratory electron transport (Sus scrofa)
Malate-aspartate shuttle (Sus scrofa)
MDH1 reduces OA (Sus scrofa)
NADH [cytosol]
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Ethanol oxidation (Sus scrofa)
ADH5 oxidises S-HMGSH to S-FGSH (Sus scrofa)
NADH [cytosol]
acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Sus scrofa)
NADH [cytosol]
ethanol + NAD+ => acetaldehyde + NADH + H+ (Sus scrofa)
NADH [cytosol]
MARC1,MARC2 reduce N-hydroxylated compounds (Sus scrofa)
NADH [cytosol]
Phase II - Conjugation of compounds (Sus scrofa)
Glucuronidation (Sus scrofa)
Formation of the active cofactor, UDP-glucuronate (Sus scrofa)
UDP-glucose is oxidised to UDP-glucuronate (Sus scrofa)
NADH [cytosol]
![NADH [cytosol] icon](/icon/R-ICO-013833.svg){kind=icon}