DHQ from DAHP dephosphorylation

Stable Identifier
R-MTU-964914
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
4/5
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DHQ from DAHP dephosphorylation
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Cyclization and dephosphorylation of DAHP, catalyzed by AroB, establishes the C6 ring in the pathway which is then only modified in the remaining five reactions (Mendonca et al, 2007).
Literature References
PubMed ID Title Journal Year
17586643 Functional characterization by genetic complementation of aroB-encoded dehydroquinate synthase from Mycobacterium tuberculosis H37Rv and its heterologous expression and purification

de Mendonça, JD, Ely, F, Palma, MS, Frazzon, J, Basso, LA, Santos, DS

J Bacteriol 2007
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Catalyst Activity

3-dehydroquinate synthase activity of AroB [cytosol]

Physical Entity
AroB [cytosol] (Mycobacterium tuberculosis)
Activity
3-dehydroquinate synthase activity (GO:0003856)
Authored
Stephan, R  (2010-09-13)
Reviewed
Warner, D  (2010-11-25)
Created
Jassal, B  (2010-09-20)
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