Reactome | RBBP6 [nucleoplasm]

RBBP6 [nucleoplasm]

Stable Identifier

R-HSA-9970176

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser for interactor UniProt:P09234 SNRPC

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External Reference Information

External Reference

UniProt:Q7Z6E9 RBBP6

Gene Names

RBBP6, P2PR, PACT, RBQ1, My038

Chain

chain:1-1792

Reference Genes

BioGPS Gene:5930 RBBP6

COSMIC - genes:RBBP6 RBBP6

CTD Gene:5930 RBBP6

dbSNP Gene:5930 RBBP6

ENSEMBL:ENSG00000122257 RBBP6

HGNC:9889 RBBP6

KEGG:hsa:5930 RBBP6

Monarch:5930 RBBP6

NCBI Gene:5930 RBBP6

OMIM:600938 RBBP6

UCSC:Q7Z6E9 RBBP6

Reference Transcript

Participates

as an output of

as an input of

Recruitment of other CPA components to pre-mRNA-bound CPA core (Homo sapiens)

as a component of

This entity regulates

Positively

CPSF3 cleaves pre-mRNA at distal 3'UTR PAS (Homo sapiens)

Other forms of this molecule

RBBP6 [cytosol]

Inferred To

rbpl-1 [nucleoplasm] (Caenorhabditis elegans)

RBBP6 [nucleoplasm] (Bos taurus)

RBBP6 [nucleoplasm] (Canis familiaris)

RBBP6 [nucleoplasm] (Dictyostelium discoideum)

RBBP6 [nucleoplasm] (Gallus gallus)

RBBP6 [nucleoplasm] (Schizosaccharomyces pombe)

RBBP6 [nucleoplasm] (Sus scrofa)

rbbp6 [nucleoplasm] (Danio rerio)

rbbp6 [nucleoplasm] (Xenopus tropicalis)

snama [nucleoplasm] (Drosophila melanogaster)

Rbbp6 [nucleoplasm] (Mus musculus)

Rbbp6 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_061173.1, NP_008841.2, NP_116015.2

OpenTargets

ENSG00000122257

ENSEMBL

ENSP00000317872, ENSP00000370427, ENST00000319715, ENSG00000122257, ENST00000452655, ENSP00000390537, ENSP00000316291, ENST00000381039, ENST00000348022

HPA

ENSG00000122257-RBBP6

GeneCards

RBBP6

PRO

Q7Z6E9

Pharos - Targets

Q7Z6E9

GlyGen

Q7Z6E9

PDB

2YSA, 3ZTG, 6E5X, 2YUR, 2C7H

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16629 SRSF7	1	SRSF7 [nucleoplasm] (R-HSA-72029)	0.655	4
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.643	3
UniProt:Q9H609 ZN576			0.643	4
UniProt:Q86VM9 ZC3H18	1	ZC3H18 [nucleoplasm] (R-HSA-9930040)	0.643	4
UniProt:Q8TEL6 TRPC4AP	1	TRPC4AP [plasma membrane] (R-HSA-3211767)	0.643	4
UniProt:Q15287 RNPS1	2	RNPS1 [cytosol] (R-HSA-159256) RNPS1 [nucleoplasm] (R-HSA-156778)	0.643	5
UniProt:P07910 HNRNPC	3	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543) HNRNPC [cytosol] (R-HSA-9715136)	0.527	3
UniProt:P49761 CLK3			0.527	3
UniProt:P49760 CLK2			0.527	2
UniProt:Q9H307 PNN	1	PNN [nucleoplasm] (R-HSA-9770779)	0.527	2
UniProt:P09234 SNRPC	1	SNRPC [nucleoplasm] (R-HSA-8865876)	0.527	2
UniProt:Q9UL40 ZN346			0.527	2
UniProt:Q16630 CPSF6	2	CPSF6(1-490)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838987) CPSF6(1-490)-FGFR1(429-822) fusion [cytosol] (R-HSA-1614368)	0.483	2

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