Reactome | ATL2 [endoplasmic reticulum membrane]

ATL2 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-9954413

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Atlastin-2 ecNumber: 3.6.5.-, ATLA2_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P13569 CFTR

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External Reference Information

External Reference

UniProt:Q8NHH9 ATL2

Gene Names

ATL2, ARL6IP2

Chain

chain:1-583

Reference Genes

BioGPS Gene:64225 ATL2

COSMIC - genes:ATL2 ATL2

CTD Gene:64225 ATL2

dbSNP Gene:64225 ATL2

ENSEMBL:ENSG00000119787 ATL2

HGNC:24047 ATL2

KEGG:hsa:64225 ATL2

Monarch:64225 ATL2

NCBI Gene:64225 ATL2

OMIM:609368 ATL2

UCSC:Q8NHH9 ATL2

Reference Transcript

Other Identifiers

11722058_s_at

11748040_a_at

11751006_a_at

1553603_PM_s_at

1553603_s_at

16896579

217580_3p_x_at

217580_PM_x_at

217580_x_at

222700_PM_at

222700_at

235848_PM_x_at

235848_x_at

237968_PM_at

237968_at

2548777

2548778

2548779

2548780

2548781

2548782

2548783

2548784

2548785

2548786

2548789

2548791

2548793

2548794

2548796

2548797

2548798

2548801

2548802

2548803

2548815

2548816

2548817

2548818

2548819

2548824

2548825

2548826

2548827

44662_at

61133_r_at

64225

8051589

82645_at

A_23_P209619

A_23_P415015

A_33_P3394040

GE672602

GE82685

GE87622

GO:0000166

GO:0003924

GO:0005515

GO:0005525

GO:0005783

GO:0005789

GO:0007029

GO:0007030

GO:0016020

GO:0016320

GO:0016787

GO:0046872

GO:0051260

GO:0061024

GO:0065003

GO:0098826

GO:0098827

GO:0140523

GO:1990809

HMNXSV003050512

Hs.150551.0.A1_3p_at

Hs.150551.0.A1_3p_x_at

Hs.167253.0.A1_3p_at

Hs.31236.0.S2_3p_at

Hs.53031.0.A1_3p_at

Hs2.27099.1.S1_3p_s_at

ILMN_1716384

PH_hs_0024157

TC02001753.hg

TC02004168.hg

This entity regulates

Positively

Nonstructural proteins form the replication complex (Homo sapiens)

Cross References

RefSeq

NP_001317387.1, NP_001317389.1, NP_001129145.1, NP_001317388.1, NP_001295005.1, NP_071769.2

OpenTargets

ENSG00000119787

ENSEMBL

ENST00000651368, ENSP00000368237, ENST00000378954, ENST00000452935, ENSP00000390743, ENSP00000384062, ENSP00000498813, ENSP00000415336, ENST00000419554, ENSG00000119787, ENST00000402054

HPA

ENSG00000119787-ATL2

GeneCards

ATL2

PRO

Q8NHH9

Pharos - Targets

Q8NHH9

GlyGen

Q8NHH9

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.564	2
UniProt:O14579 COPE	4	COPE [endoplasmic reticulum membrane] (R-HSA-6810959) COPE [Golgi membrane] (R-HSA-6808743) COPE [transport vesicle] (R-HSA-6808745) COPE [cytosol] (R-HSA-199969)	0.527	2
UniProt:Q9Y678 COPG1	4	COPG1 [endoplasmic reticulum membrane] (R-HSA-6810960) COPG1 [Golgi membrane] (R-HSA-6808747) COPG1 [transport vesicle] (R-HSA-6808749) COPG1 [cytosol] (R-HSA-199987)	0.527	2
UniProt:Q6DD88 ATLA3			0.527	3
UniProt:Q5T4F4 ZFY27			0.499	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.483	4

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