Reactome | ODAM [extracellular region]

ODAM [extracellular region]

Stable Identifier

R-HSA-977149

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Odontogenic ameloblast-associated protein, Apin, ODAM_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Amyloid fiber formation (Homo sapiens)
  - Amyloid fibrils have additional components (Homo sapiens)
    - Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
      - Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
        
        Odontogenic ameloblast-associated protein amyloid fibrils [extracellular region] (Homo sapiens)
        
        ODAM [extracellular region] (Homo sapiens)
    - Amyloid fibrils [plasma membrane] (Homo sapiens)
      - Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
        
        Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
        
        Odontogenic ameloblast-associated protein amyloid fibrils [extracellular region] (Homo sapiens)
        
        ODAM [extracellular region] (Homo sapiens)
  - Amyloid precursor proteins form ordered fibrils (Homo sapiens)
    - Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
      - Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
        
        Odontogenic ameloblast-associated protein amyloid fibrils [extracellular region] (Homo sapiens)
        
        ODAM [extracellular region] (Homo sapiens)
    - Amyloid fibril monomers [extracellular region] (Homo sapiens)
      - Localized amyloid fibril monomers [extracellular region] (Homo sapiens)
        
        ODAM [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:A1E959 ODAM

Gene Names

ODAM, APIN

Chain

signal peptide:1-15, chain:16-279

Reference Genes

BioGPS Gene:54959 ODAM

COSMIC (genes):ODAM ODAM

CTD Gene:54959 ODAM

dbSNP Gene:54959 ODAM

ENSEMBL:ENSG00000109205 ODAM

ENSEMBL_homo_sapiens_GENE:ENSG00000109205.17 ODAM

HGNC:26043 ODAM

KEGG Gene (Homo sapiens):54959 ODAM

Monarch:54959 ODAM

NCBI Gene:54959 ODAM

OMIM:614843 ODAM

UCSC:A1E959 ODAM

Reference Transcript

RefSeq:NM_017855.3 ODAM

Other Identifiers

11733433_a_at

16967449

220133_PM_at

220133_at

2730280

2730282

2730283

2730285

2730286

2730287

2730290

2730292

2730293

2730294

2730295

2730296

2730297

2730298

54959

61069_at

8095456

A_14_P105882

A_23_P58228

GE82235

GO:0001934

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005856

GO:0006954

GO:0007010

GO:0009611

GO:0010628

GO:0031214

GO:0032956

GO:0036211

GO:0042060

GO:0042475

GO:0043226

GO:0043547

GO:0048856

GO:0060054

GO:0071944

GO:0072686

GO:0099512

HMNXSV003012732

ILMN_1729851

PH_hs_0008478

TC04000380.hg

g8923478_3p_at

Participates

as a member of

Localized amyloid fibril monomers [extracellular region] (Homo sapiens)

as a repeated unit of

Odontogenic ameloblast-associated protein amyloid fibrils [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_060325.3

OpenTargets

ENSG00000109205

GeneCards

A1E959

HPA

ENSG00000109205-ODAM

Ensembl

ENSP00000507531, ENSP00000379401, ENSG00000109205, ENST00000683306, ENST00000396094

PRO

A1E959

Pharos - Targets

A1E959

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.564	2
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [extracellular region] (R-HSA-6806206) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [cytosol] (R-HSA-373639)	0.556	3
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.556	3
UniProt:O95231 VENTX	1	VENTX [nucleoplasm] (R-HSA-8853887)	0.556	3
UniProt:Q9H0E2 TOLLIP	4	TOLLIP [cytosol] (R-HSA-446885) TOLLIP [azurophil granule lumen] (R-HSA-6799709) TOLLIP [extracellular region] (R-HSA-6800448) TOLLIP [specific granule lumen] (R-HSA-6799719)	0.553	2