F-box protein

Stable Identifier
R-HSA-976085
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
Synonyms
substrate recognition component of a SCF E3 ligase complex
Locations in the PathwayBrowser
Summation

F-box proteins were first characterized as components of SCF ubiquitin-ligase complexes (named after their main components, SkpI, Cullin, and an F-box protein), in which they bind substrates for ubiquitin-mediated proteolysis. The F-box motif links the F-box protein to other components of the SCF complex by binding the core SCF component SkpI.

Participants
Participant Of
Inferred To