Reactome | MGAT4C [Golgi membrane]

MGAT4C [Golgi membrane]

Stable Identifier

R-HSA-975907

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C, MGT4C_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        Late SARS-CoV-2 Infection Events (Homo sapiens)
        
        Translation of Structural Proteins (Homo sapiens)
        
        Maturation of spike protein (Homo sapiens)
        
        Spike trimer glycoside chains get additional branches (Homo sapiens)
        
        MGAT4s [Golgi membrane] (Homo sapiens)
        
        MGAT4C [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UBM8 MGAT4C

Gene Names

MGAT4C

Chain

chain:1-478

Reference Genes

BioGPS Gene:25834 MGAT4C

COSMIC (genes):MGAT4C MGAT4C

CTD Gene:25834 MGAT4C

dbSNP Gene:25834 MGAT4C

ENSEMBL:ENSG00000182050 MGAT4C

ENSEMBL_homo_sapiens_GENE:ENSG00000182050.14 MGAT4C

HGNC:30871 MGAT4C

KEGG Gene (Homo sapiens):25834 MGAT4C

Monarch:25834 MGAT4C

NCBI Gene:25834 MGAT4C

OMIM:607385 MGAT4C

UCSC:Q9UBM8 MGAT4C

Reference Transcript

Other Identifiers

11741253_a_at

11761906_a_at

16768154

207447_PM_s_at

207447_s_at

240649_PM_at

240649_at

25834

34150_at

3464418

3464419

3464420

3464421

3464422

3464423

3464424

3464425

3464426

3464427

3464428

3464429

3464430

3464431

3464432

3464435

3464436

3464437

3464438

3464439

3464440

3464444

3464449

3464467

3464468

3464473

3464478

3464493

3464498

71428_at

7965231

A_33_P3221723

GE496471

GE733049

GE81807

GO:0000139

GO:0003824

GO:0005794

GO:0006486

GO:0006487

GO:0008375

GO:0008454

GO:0016020

GO:0016740

GO:0016757

GO:0019082

GO:0036211

GO:0043226

GO:0046872

GO:0140096

GO:1901135

HMNXSV003030603

Hs.215801.0.S1_3p_at

ILMN_1704904

ILMN_2117736

PH_hs_0019078

PH_hs_0025159

TC12002988.hg

g7019406_3p_a_at

p3319

Participates

as a member of

MGAT4s [Golgi membrane] (Homo sapiens)

Inferred To

LOC427873 [Golgi membrane] (Gallus gallus)

Homologues of MGAT4C [Golgi membrane] (Sus scrofa)

Mgat4b [Golgi membrane] (Drosophila melanogaster)

Mgat4c [Golgi membrane] (Mus musculus)

Mgat4c [Golgi membrane] (Rattus norvegicus)

MGAT4C [Golgi membrane] (Bos taurus)

MGAT4C [Golgi membrane] (Canis familiaris)

MGAT4C [Golgi membrane] (Sus scrofa)

mgat4c [Golgi membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_005268836.1, XP_016874637.1, XP_005268833.1, XP_016874638.1, XP_016874636.1, XP_016874635.1, XP_011536458.1, NP_037376.2, XP_016874634.1, XP_011536459.1, XP_016874639.1

OpenTargets

ENSG00000182050

HPA

ENSG00000182050-MGAT4C

GeneCards

Q9UBM8

Ensembl

ENST00000548651, ENST00000611864, ENSG00000182050, ENSP00000477650, ENST00000621808, ENSP00000447253, ENST00000620241, ENST00000552808, ENSP00000446647, ENSP00000478300, ENSP00000481096

PRO

Q9UBM8

Pharos - Targets

Q9UBM8

HMDB Protein

HMDBP11827

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01130 LDLR	4	LDLR [endolysosome membrane] (R-HSA-6784818) LDLR [endosome membrane] (R-HSA-171127) LDLR [clathrin-coated endocytic vesicle membrane] (R-HSA-171105) LDLR [plasma membrane] (R-HSA-171053)	0.527	2
UniProt:O75581 LRP6	8	p-T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-205884) p-S1490-LRP6 [plasma membrane] (R-HSA-206156) LRP6 [early endosome membrane] (R-HSA-5368481) p-LRP6 [early endosome membrane] (R-HSA-5368496) LRP6N [extracellular region] (R-HSA-5334021) p-2S,S1490,2T-LRP6 [plasma membrane] (R-HSA-1458894) p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane] (R-HSA-1458895) LRP6 [plasma membrane] (R-HSA-206252)	0.527	2
UniProt:Q16706 MAN2A1	2	MAN2A1 [transport vesicle] (R-HSA-8847487) MAN2A1 [Golgi membrane] (R-HSA-975823)	0.527	2
UniProt:P48645 NMU	1	NMU [extracellular region] (R-HSA-964817)	0.527	2
UniProt:O75197 LRP5	5	LRP5 [plasma membrane] (R-HSA-201671) p-5S,5T-LRP5 [plasma membrane] (R-HSA-1458893) p-3S,2T-LRP5 [plasma membrane] (R-HSA-1458905) LRP5 [early endosome membrane] (R-HSA-5368479) LRP5 D666_L809del [plasma membrane] (R-HSA-5339694)	0.527	2
UniProt:P22466 GAL	1	GAL [extracellular region] (R-HSA-389038)	0.527	2

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