Reactome | IKBIP [endoplasmic reticulum membrane]

IKBIP [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-9749482

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

IKIP, Inhibitor of nuclear factor kappa-B kinase-interacting protein

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q70UQ0 IKBIP

Gene Names

IKBIP, IKIP

Chain

chain:1-350

Reference Genes

BioGPS Gene:121457 IKBIP

COSMIC - genes:IKBIP IKBIP

CTD Gene:121457 IKBIP

dbSNP Gene:121457 IKBIP

ENSEMBL:ENSG00000166130 IKBIP

HGNC:26430 IKBIP

KEGG:hsa:121457 IKBIP

Monarch:121457 IKBIP

NCBI Gene:121457 IKBIP

OMIM:609861 IKBIP

UCSC:Q70UQ0 IKBIP

Reference Transcript

Participates

as an output of

TP53 stimulates IKBIP gene expression (Homo sapiens)

as a component of

CHUK:IKBKB:IKBIP [endoplasmic reticulum membrane] (Homo sapiens)

as an input of

IKBIP binds IKBKB and CHUK (Homo sapiens)

Inferred To

ikbip [endoplasmic reticulum membrane] (Danio rerio)

IKBIP [endoplasmic reticulum membrane] (Bos taurus)

Cross References

RefSeq

NP_963907.1, NP_963906.1, NP_710154.1

ENSEMBL

ENST00000299157, ENSP00000299157, ENST00000342502, ENSG00000166130, ENST00000393042, ENSP00000343471, ENSP00000376762

OpenTargets

ENSG00000166130

GeneCards

IKBIP

HPA

ENSG00000166130-IKBIP

PRO

Q70UQ0

Pharos - Targets

Q70UQ0

GlyGen

Q70UQ0

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P15173 MYOG	1	MYOG [nucleoplasm] (R-HSA-445160)	0.666	4
UniProt:Q93097 WNT2B	9	WNT2B(?-391) [extracellular region] (R-HSA-517467) N4GlycoAsn-PalmS WNT2B(1-391) [extracellular exosome] (R-HSA-3781959) N4GlycoAsn-PalmS WNT2B(1-391) [endocytic vesicle membrane] (R-HSA-3781976) WNT2B(1-391) [endoplasmic reticulum lumen] (R-HSA-3238286) N4GlycoAsn-WNT2B(1-391) [endoplasmic reticulum lumen] (R-HSA-3238269) N4GlycoAsn-PalmS WNT2B(1-391) [endoplasmic reticulum lumen] (R-HSA-3238367) N4GlycoAsn-PalmS WNT2B(1-391) [Golgi lumen] (R-HSA-3247776) N4GlycoAsn-PalmS WNT2B(1-391) [extracellular region] (R-HSA-3247812) N4GlycoAsn-PalmS WNT2B(1-391) [plasma membrane] (R-HSA-3247782)	0.657	9
UniProt:Q5VU62 Q5VU62			0.556	3
UniProt:Q9BUW7 BBLN			0.556	3
UniProt:P19012 KRT15	1	KRT15 [cytosol] (R-HSA-6809589)	0.556	3
UniProt:P37198 NUP62	2	NUP62 [nuclear envelope] (R-HSA-157713) NUP62 [cytosol] (R-HSA-9634226)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:Q9NWB7 IFT57	2	IFT57 [cilium] (R-HSA-5610389) IFT57 [ciliary tip] (R-HSA-5625363)	0.527	2
UniProt:Q13751 LAMB3	3	LAMB3(18-?) [extracellular region] (R-HSA-2533880) LAMB3(?-1172) [extracellular region] (R-HSA-2533848) LAMB3 [extracellular region] (R-HSA-445992)	0.527	2
UniProt:Q9NVF7 FBX28			0.527	2
UniProt:Q9Y240 CLC11			0.527	3
UniProt:Q13753 LAMC2	3	LAMC2(22-?) [extracellular region] (R-HSA-2533906) LAMC2(?-1193) [extracellular region] (R-HSA-2533876) LAMC2 [extracellular region] (R-HSA-446012)	0.527	2
UniProt:Q32P28 P3H1	1	LEPRE1 [endoplasmic reticulum lumen] (R-HSA-1650318)	0.527	2
UniProt:Q9HC29 NOD2	1	NOD2 [cytosol] (R-HSA-168411)	0.508	4
UniProt:O14920 IKBKB	3	IKBKB [cytosol] (R-HSA-168114) p-S177,S181-IKBKB [cytosol] (R-HSA-202506) IKBKB Q432Pfs*62 [cytosol] (R-HSA-9628518)	0.499	3

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