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RAC2 [mitochondrial outer membrane]
Stable Identifier
R-HSA-9714496
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Synonyms
Rac2
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 binds effectors at the mitochondrial outer membrane (Homo sapiens)
RAC2:GTP [mitochondrial outer membrane] (Homo sapiens)
RAC2 [mitochondrial outer membrane] (Homo sapiens)
RAC2:GTP:RAC2 mitochondrial effectors [mitochondrial outer membrane] (Homo sapiens)
RAC2:GTP [mitochondrial outer membrane] (Homo sapiens)
RAC2 [mitochondrial outer membrane] (Homo sapiens)
RAC2 translocates to the mitochondrial membrane (Homo sapiens)
RAC2:GTP [mitochondrial outer membrane] (Homo sapiens)
RAC2 [mitochondrial outer membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15153 RAC2
Gene Names
RAC2
Chain
chain:1-189, propeptide:190-192
Reference Genes
BioGPS Gene:5880 RAC2
COSMIC (genes):RAC2 RAC2
CTD Gene:5880 RAC2
dbSNP Gene:5880 RAC2
ENSEMBL:ENSG00000128340 RAC2
HGNC:9802 RAC2
KEGG Gene (Homo sapiens):5880 RAC2
Monarch:5880 RAC2
NCBI Gene:5880 RAC2
OMIM:602049 RAC2
UCSC:P15153 RAC2
Reference Transcript
RefSeq:NM_002872.4 RAC2
Other Identifiers
0002690095
11744263_s_at
16934749
207419_3p_s_at
207419_s_at
213603_s_at
2989055
32736_at
32737_at
3960062
3960063
3960064
3960065
3960066
3960067
3960069
3960071
3960079
3960080
3960081
5880
8075910
A_23_P218770
A_23_P218774
A_24_P228717
GE80267
GE81848
GO:0000166
GO:0000902
GO:0002376
GO:0003674
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005635
GO:0005737
GO:0005829
GO:0005856
GO:0005884
GO:0005886
GO:0005925
GO:0005938
GO:0006464
GO:0006605
GO:0006810
GO:0006935
GO:0007005
GO:0007010
GO:0007015
GO:0007155
GO:0007163
GO:0007165
GO:0007186
GO:0007264
GO:0008045
GO:0008150
GO:0008283
GO:0008284
GO:0008360
GO:0010310
GO:0010592
GO:0010810
GO:0015031
GO:0016020
GO:0016192
GO:0016601
GO:0019887
GO:0019899
GO:0019901
GO:0022607
GO:0030027
GO:0030031
GO:0030036
GO:0030154
GO:0030234
GO:0030670
GO:0030865
GO:0031410
GO:0032956
GO:0040011
GO:0042129
GO:0042592
GO:0042995
GO:0043167
GO:0043226
GO:0043231
GO:0043304
GO:0043652
GO:0045453
GO:0045454
GO:0045859
GO:0048856
GO:0048870
GO:0051056
GO:0051897
GO:0060263
GO:0060753
GO:0061024
GO:0070062
GO:0071593
GO:0090023
GO:1902622
GO:1903955
HMNXSV003032615
Hs.301175.1.S1_3p_s_at
ILMN_1709795
M64595_at
PH_hs_0015519
TC22000725.hg
Participates
as a component of
RAC2:GTP [mitochondrial outer membrane] (Homo sapiens)
Other forms of this molecule
RAC2 [endoplasmic reticulum membrane]
RAC2 [phagocytic vesicle membrane]
RAC2 [cytosol]
RAC2 [plasma membrane]
Inferred To
Rac2 [mitochondrial outer membrane]
(Drosophila melanogaster)
Rac2 [mitochondrial outer membrane]
(Mus musculus)
Rac2 [mitochondrial outer membrane]
(Rattus norvegicus)
racG [mitochondrial outer membrane]
(Dictyostelium discoideum)
racE [mitochondrial outer membrane]
(Dictyostelium discoideum)
racC [mitochondrial outer membrane]
(Dictyostelium discoideum)
racF2 [mitochondrial outer membrane]
(Dictyostelium discoideum)
racN [mitochondrial outer membrane]
(Dictyostelium discoideum)
Homologues of RAC2 [mitochondrial outer membrane]
(Caenorhabditis elegans)
Homologues of RAC2 [mitochondrial outer membrane]
(Dictyostelium discoideum)
Homologues of RAC2 [mitochondrial outer membrane]
(Drosophila melanogaster)
racJ [mitochondrial outer membrane]
(Dictyostelium discoideum)
rac1A [mitochondrial outer membrane]
(Dictyostelium discoideum)
racL [mitochondrial outer membrane]
(Dictyostelium discoideum)
rac-2 [mitochondrial outer membrane]
(Caenorhabditis elegans)
rac1C [mitochondrial outer membrane]
(Dictyostelium discoideum)
racH [mitochondrial outer membrane]
(Dictyostelium discoideum)
RAC2 [mitochondrial outer membrane]
(Bos taurus)
RAC2 [mitochondrial outer membrane]
(Caenorhabditis elegans)
RAC2 [mitochondrial outer membrane]
(Canis familiaris)
RAC2 [mitochondrial outer membrane]
(Dictyostelium discoideum)
RAC2 [mitochondrial outer membrane]
(Gallus gallus)
RAC2 [mitochondrial outer membrane]
(Sus scrofa)
RAC2 [mitochondrial outer membrane]
(Xenopus tropicalis)
racD [mitochondrial outer membrane]
(Dictyostelium discoideum)
racB [mitochondrial outer membrane]
(Dictyostelium discoideum)
ced-10 [mitochondrial outer membrane]
(Caenorhabditis elegans)
rac2 [mitochondrial outer membrane]
(Danio rerio)
racF1 [mitochondrial outer membrane]
(Dictyostelium discoideum)
Rac1 [mitochondrial outer membrane]
(Drosophila melanogaster)
racQ [mitochondrial outer membrane]
(Dictyostelium discoideum)
rac1B [mitochondrial outer membrane]
(Dictyostelium discoideum)
racM [mitochondrial outer membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_002863.1
Target Pathogen
5b354852be737e166372e92f
OpenTargets
ENSG00000128340
GeneCards
P15153
HPA
ENSG00000128340-RAC2
Ensembl
ENST00000249071
,
ENSP00000249071
,
ENSG00000128340
PRO
P15153
Orphanet
18485
HMDB Protein
HMDBP01788
PDB
2W2V
,
2W2T
,
1DS6
,
2W2X
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P53365 ARFIP2
1
ARFIP2 [cytosol]
(R-HSA-6813848)
0.556
3
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [ChEBI:16851]
7
PI(3,5)P2 [plasma membrane]
(R-ALL-1806224)
PI(3,5)P2 [phagophore assembly site membrane]
(R-ALL-5692959)
PI(3,5)P2 [Golgi membrane]
(R-ALL-1806290)
PI(3,5)P2 [early endosome membrane]
(R-ALL-1806205)
PI(3,5)P2 [late endosome membrane]
(R-ALL-1806289)
PI(3,5)P2 [endoplasmic reticulum membrane]
(R-ALL-6809774)
PI(3,5)P2 [lysosomal membrane]
(R-ALL-5334668)
0.462
2
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate [ChEBI:16618]
6
PI(3,4,5)P3 [endocytic vesicle membrane]
(R-ALL-917725)
PIP3 [plasma membrane]
(R-ALL-38117)
PI(3,4,5)P3 [endosome membrane]
(R-ALL-917716)
PI(3,4,5)P3 [early endosome membrane]
(R-ALL-8849955)
PI(3,4,5)P3 [cytoplasmic vesicle membrane]
(R-ALL-8874468)
PI(3,4,5)P3 [plasma membrane]
(R-ALL-179838)
0.462
2
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [ChEBI:18348]
6
PI(4,5)P2 [endoplasmic reticulum membrane]
(R-ALL-2023856)
PI(4,5)P2 [plasma membrane]
(R-ALL-179856)
PI(4,5)P2 [Golgi membrane]
(R-ALL-1806165)
PI(4,5)P2 [nucleoplasm]
(R-ALL-6810412)
PI(4,5)P2 [cytoplasmic vesicle membrane]
(R-ALL-8874467)
PI(4,5)P2 [early endosome membrane]
(R-ALL-8849966)
0.462
2
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