Reactome | RAP1GDS1 [mitochondrial outer membrane]

RAP1GDS1 [mitochondrial outer membrane]

Stable Identifier

R-HSA-9693756

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Vimar

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P52306 RAP1GDS1

Gene Names

RAP1GDS1, SMGGDS

Chain

chain:1-607

Reference Genes

COSMIC (genes):RAP1GDS1 RAP1GDS1

dbSNP Gene:5910 RAP1GDS1

ENSEMBL:ENSG00000138698 RAP1GDS1

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449620 REP			0.836	6
UniProt:P61586 RHOA	6	RHOA [plasma membrane] (R-HSA-194510) RHOA [cell junction] (R-HSA-2134503) RHOA [cytosol] (R-HSA-194866) RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082)	0.788	7
UniProt:P63000 RAC1	6	RAC1 [plasma membrane] (R-HSA-351141) RAC1 [cytosol] (R-HSA-442615) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802) RAC1 [secretory granule membrane] (R-HSA-6804770) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076)	0.738	4
UniProt:Q9UF11 PKHB1			0.666	5
UniProt:P08134 RHOC	3	RHOC [plasma membrane] (R-HSA-194870) RHOC [cytosol] (R-HSA-194853) RHOC [endoplasmic reticulum membrane] (R-HSA-9714362)	0.643	4
UniProt:Q9NS73-5 MBIP			0.556	3
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:P60953 CDC42	3	CDC42 [cytosol] (R-HSA-442630) CDC42 [plasma membrane] (R-HSA-449545) CDC42 [endoplasmic reticulum membrane] (R-HSA-5672086)	0.547	2
UniProt:Q4LDG9 DNAL1			0.527	3
UniProt:Q8TCD5 NT5C	1	NT5C [cytosol] (R-HSA-109467)	0.527	2
UniProt:P60763 RAC3	3	RAC3 [endoplasmic reticulum membrane] (R-HSA-9714693) RAC3 [plasma membrane] (R-HSA-195338) RAC3 [cytosol] (R-HSA-195335)	0.527	2
UniProt:O95057 DIRA1			0.527	3
UniProt:Q96HU8 DIRA2			0.527	3
UniProt:Q9BQS6 HSPB9			0.527	2
UniProt:Q9Y3Q8 T22D4			0.527	4
UniProt:Q9Y3L5 RAP2C	2	RAP2C [plasma membrane] (R-HSA-6804983) RAP2C [tertiary granule membrane] (R-HSA-6804975)	0.527	3
UniProt:P59190 RAB15	2	GGC-RAB15 [cytosol] (R-HSA-8873782) RAB15 [cytosol] (R-HSA-8873682)	0.527	3
UniProt:P15153 RAC2	5	RAC2 [endoplasmic reticulum membrane] (R-HSA-9714482) RAC2 [mitochondrial outer membrane] (R-HSA-9714496) RAC2 [phagocytic vesicle membrane] (R-HSA-5668620) RAC2 [cytosol] (R-HSA-195343) RAC2 [plasma membrane] (R-HSA-195339)	0.527	2
UniProt:Q5HYI8 RABL3			0.527	3
UniProt:P62834 RAP1A	4	RAP1A [plasma membrane] (R-HSA-354118) RAP1A [endosome membrane] (R-HSA-190053) RAP1A [cytosol] (R-HSA-169884) RAP1A [specific granule membrane] (R-HSA-6806137)	0.527	3
UniProt:Q6NXR0 IIGP5			0.527	2
UniProt:P61224 RAP1B	2	RAP1B [plasma membrane] (R-HSA-377590) RAP1B [azurophil granule membrane] (R-HSA-6804972)	0.527	2
UniProt:P56559 ARL4C	1	ARL4C [plasma membrane] (R-HSA-9618406)	0.527	3