Reactome | 3OHR141-RCCD1 [cytosol]

3OHR141-RCCD1 [cytosol]

Stable Identifier

R-HSA-9629871

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

RCC1 domain-containing protein 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A6NED2 RCCD1

Gene Names

RCCD1

Chain

chain:1-376

Reference Genes

BioGPS Gene:91433 RCCD1

COSMIC (genes):RCCD1 RCCD1

CTD Gene:91433 RCCD1

dbSNP Gene:91433 RCCD1

ENSEMBL:ENSG00000166965 RCCD1

HGNC:30457 RCCD1

Monarch:91433 RCCD1

NCBI Gene:91433 RCCD1

OMIM:617997 RCCD1

UCSC:A6NED2 RCCD1

Reference Transcript

Other Identifiers

11729737_a_at

11729738_x_at

16805090

226488_PM_at

226488_at

3608573

3608575

3608576

3608577

3608578

3608579

3608580

3608581

3608582

3608583

3608584

3608585

3608586

3608587

3608588

3608589

3608590

3608591

58007_at

58245_at

7986186

91433

A_23_P106433

A_23_P106439

GE61837

GO:0005515

GO:0005694

GO:0005829

GO:0005886

GO:0006325

GO:0043226

HMNXSV003046201

Hs.14870.0.A1_3p_at

Hs.287295.0.A1_3p_at

ILMN_1797738

ILMN_2391324

ILMN_2409318

PH_hs_0038664

TC15000874.hg

p33782

Participates

as an output of

KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Homo sapiens)

Other forms of this molecule

RCCD1 [cytosol]

Inferred To

Dmel\CG6678 [cytosol] (Drosophila melanogaster)

rccd1 [cytosol] (Xenopus tropicalis)

Rccd1 [cytosol] (Mus musculus)

Rccd1 [cytosol] (Rattus norvegicus)

RCCD1 [cytosol] (Bos taurus)

RCCD1 [cytosol] (Canis familiaris)

RCCD1 [cytosol] (Sus scrofa)

3OHR141-RCCD1 [cytosol] (Caenorhabditis elegans)

Modified Residues

Name

(3R)-3-hydroxy-L-arginine at 141

Coordinate

141

PsiMod Name

(3R)-3-hydroxy-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to (3R)-3-hydroxy-L-arginine.

Cross References

ENSEMBL

ENST00000394258, ENSP00000377801, ENSP00000451963, ENST00000556618

OpenTargets

ENSG00000166965

HPA

ENSG00000166965-RCCD1

PRO

A6NED2

Pharos - Targets

A6NED2

PDB

6F4R, 6F4S, 6F4T

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N371 KDM8	1	KDM8 [cytosol] (R-HSA-9629868)	0.623	4
UniProt:P13994 YJU2B			0.527	3
UniProt:Q9P2Y4 ZN219			0.527	2
UniProt:Q7L273 KCTD9			0.527	3
UniProt:Q9UPT6 JIP3			0.527	4
UniProt:P30838 ALDH3A1	1	ALDH3A1 [cytosol] (R-HSA-5692291)	0.527	2
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2
UniProt:Q15042 RAB3GAP1	2	RAB3GAP1 [endoplasmic reticulum membrane] (R-HSA-508581) RAB3GAP1 [cytosol] (R-HSA-8877982)	0.527	2
UniProt:Q14642 INPP5A	1	INPP5A [plasma membrane] (R-HSA-1604583)	0.527	3
UniProt:Q71U36 TUBA1A	9	TUBA1A [cytosol] (R-HSA-191689) TUBA1A [axonemal microtubule] (R-HSA-5610433) TUBA1A(1-450) [cytosol] (R-HSA-8955577) Polyglutamyl-TUBA1A [cytosol] (R-HSA-8867408) L-isoglutamyl polyglycyl-TUBA1A [cytosol] (R-HSA-8867428) TUBA1A unfolded [cytosol] (R-HSA-392767) TUBA1A folding intermediate [cytosol] (R-HSA-392805) Ac K40 TUBA1A [axonemal microtubule] (R-HSA-5624852) AcK-TUBA1A [cytosol] (R-HSA-5618312)	0.527	2
UniProt:P62875 POLR2L	2	POLR2L [cytosol] (R-HSA-1964467) POLR2L [nucleoplasm] (R-HSA-83715)	0.527	3
UniProt:O60271 SPAG9	1	SPAG9 [cytosol] (R-HSA-375975)	0.527	3

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