Reactome | POLR2L [cytosol]

POLR2L [cytosol]

Stable Identifier

R-HSA-1964467

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

HsRPABC5, DNA-directed RNA polymerase II 7.6 kDa polypeptide (EC 2.7.7.6) (RPB10) (RPB7.6), DNA-directed RNA polymerase II 7.6 kDa polypeptide , RPB10, RPB7.6, RPABC5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P62875 POLR2L

Gene Names

POLR2L

Chain

chain:1-67

Reference Genes

BioGPS Gene:5441 POLR2L

COSMIC (genes):POLR2L POLR2L

CTD Gene:5441 POLR2L

dbSNP Gene:5441 POLR2L

ENSEMBL:ENSG00000177700 POLR2L

HGNC:9199 POLR2L

KEGG:hsa:5441 POLR2L

Monarch:5441 POLR2L

NCBI Gene:5441 POLR2L

OMIM:601189 POLR2L

UCSC:P62875 POLR2L

Reference Transcript

RefSeq:NM_021128.4 POLR2L

Other Identifiers

11716442_a_at

11753875_a_at

11753876_x_at

16734154

202586_PM_at

202586_at

211730_PM_s_at

211730_s_at

3358494

3358495

3358498

3358499

3358500

35841_at

503_at

5441

78238_at

7945573

A_23_P33015

GE79031

GO:0000428

GO:0001054

GO:0001055

GO:0001056

GO:0003677

GO:0003824

GO:0003899

GO:0005515

GO:0005634

GO:0005654

GO:0005665

GO:0005666

GO:0005730

GO:0005736

GO:0005829

GO:0006351

GO:0006355

GO:0006356

GO:0006360

GO:0006366

GO:0006399

GO:0008270

GO:0016740

GO:0042797

GO:0043226

GO:0046872

GO:0140098

HMNXSV003013515

Hs.71618.0.S2_3p_at

ILMN_1670037

TC11001251.hg

U37690_at

g13543491_3p_s_at

Participates

as a component of

RNA Polymerase III Holoenzyme [cytosol] (Homo sapiens)

Other forms of this molecule

POLR2L [nucleoplasm]

Cross References

RefSeq

NP_066951.1

OpenTargets

ENSG00000177700

ENSEMBL

ENSP00000324124, ENST00000322028, ENST00000534030, ENSP00000432807

HPA

ENSG00000177700-POLR2L

PRO

P62875

Pharos - Targets

P62875

HMDB Protein

HMDBP11915

PDB

8IUE, 5IY6, 7DU2, 7OBB, 7AE3, 7VBC, 7FJI, 8IUH, 5IY7, 7LBM, 5IY8, 6DRD, 7A6H, 7OBA, 5IY9, 5IYB, 7VBB, 5IYA, 7DN3, 5IYD, 5IYC, 7D58, 7AEA, 7FJJ, 7OB9, 7AE1, 7AST, 7VBA, 8A43, 8ITY, 7D59, 6O9L, 6XRE

Interactors (44)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.867	9
UniProt:O15514 POLR2D	1	POLR2D [nucleoplasm] (R-HSA-63508)	0.738	5
UniProt:Q9BWH6 RPAP1			0.666	5
UniProt:Q8N9N5 BANP	1	BANP [nucleoplasm] (R-HSA-3221973)	0.556	3
UniProt:P60900 PSMA6	2	PSMA6 [cytosol] (R-HSA-68734) PSMA6 [nucleoplasm] (R-HSA-174314)	0.556	3
UniProt:Q15645 PCH2			0.556	3
UniProt:Q8IXK0 PHC2	1	PHC2 [nucleoplasm] (R-HSA-389112)	0.556	3
UniProt:Q96RE7 NACC1			0.556	3
UniProt:O43829 ZBT14			0.556	3
UniProt:Q9NVV9 THAP1			0.556	3
UniProt:O95994 AGR2			0.556	3
UniProt:Q04864-2 REL			0.556	3
UniProt:Q9NTX9 F217B			0.556	3
UniProt:Q96JM7 LMBL3			0.556	3
UniProt:Q96R06 SPAG5			0.556	3
UniProt:Q13625-3 TP53BP2			0.556	3
UniProt:Q04864 REL	2	REL [cytosol] (R-HSA-1168579) REL [nucleoplasm] (R-HSA-1168585)	0.556	3
UniProt:P38432 COIL			0.556	3
UniProt:P52434 POLR2H	2	POLR2H [cytosol] (R-HSA-1964450) POLR2H [nucleoplasm] (R-HSA-63523)	0.527	2
UniProt:Q9GZS1 POLR1E	1	POLR1E [nucleoplasm] (R-HSA-5419294)	0.527	3
UniProt:Q9H1D9 POLR3F	2	POLR3F [cytosol] (R-HSA-1964434) POLR3F [nucleoplasm] (R-HSA-83708)	0.527	3
UniProt:P0DPB6 RPAC2			0.527	2
UniProt:A0JLT2 MED19	1	MED19 [nucleoplasm] (R-HSA-556819)	0.527	2
UniProt:O14802 POLR3A	2	POLR3A [cytosol] (R-HSA-1964433) POLR3A [nucleoplasm] (R-HSA-83700)	0.527	3
UniProt:Q9Y535 POLR3H	2	POLR3H [cytosol] (R-HSA-1964440) POLR3H [nucleoplasm] (R-HSA-83710)	0.527	3
UniProt:Q9H9Y6 POLR1B	1	POLR1B [nucleoplasm] (R-HSA-63496)	0.527	3
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.527	3
UniProt:O00267 SUPT5H	1	p-SUPT5H [nucleoplasm] (R-HSA-3009372)	0.527	2
UniProt:Q9H9Y4 GPN2			0.527	3
UniProt:A6NED2 RCCD1	2	3OHR141-RCCD1 [cytosol] (R-HSA-9629871) RCCD1 [cytosol] (R-HSA-9629873)	0.527	3
UniProt:P05423 POLR3D	2	POLR3D [nucleoplasm] (R-HSA-83704) POLR3D [cytosol] (R-HSA-1964429)	0.527	3
UniProt:P61218 POLR2F	2	POLR2F [cytosol] (R-HSA-1964441) POLR2F [nucleoplasm] (R-HSA-83714)	0.527	4
UniProt:Q9NVU0 POLR3E	2	POLR3E [cytosol] (R-HSA-1964451) POLR3E [nucleoplasm] (R-HSA-83706)	0.527	3
UniProt:P19387 POLR2C	1	POLR2C [nucleoplasm] (R-HSA-63506)	0.527	3
UniProt:O95602 POLR1A	1	POLR1A [nucleoplasm] (R-HSA-63494)	0.527	3
UniProt:P52435 POLR2J	1	POLR2J [nucleoplasm] (R-HSA-63531)	0.527	4
UniProt:Q9BT43 POLR3GL	2	POLR3GL [nucleoplasm] (R-HSA-1964458) POLR3GL [cytosol] (R-HSA-1964463)	0.527	3
UniProt:P30876 POLR2B	1	POLR2B [nucleoplasm] (R-HSA-63504)	0.527	3
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.527	3
UniProt:Q9NWS0 PIHD1			0.527	2
UniProt:Q96P16 RPRD1A	1	RPRD1A [nucleoplasm] (R-HSA-6814899)	0.527	3
UniProt:Q9NQG5 RPRD1B	1	RPRD1B [nucleoplasm] (R-HSA-6814894)	0.527	3
UniProt:Q9NW08 POLR3B	2	POLR3B [cytosol] (R-HSA-1964435) POLR3B [nucleoplasm] (R-HSA-83702)	0.527	3
UniProt:P62487 POLR2G	1	POLR2G [nucleoplasm] (R-HSA-63517)	0.527	3

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