Reactome | RAB3GAP1 [endoplasmic reticulum membrane]

RAB3GAP1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-508581

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Rab3 GTPase-activating protein catalytic subunit, RB3GP_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15042 RAB3GAP1

Gene Names

RAB3GAP1, KIAA0066, RAB3GAP

Chain

chain:1-981

Reference Genes

BioGPS Gene:22930 RAB3GAP1

COSMIC (genes):RAB3GAP1 RAB3GAP1

CTD Gene:22930 RAB3GAP1

dbSNP Gene:22930 RAB3GAP1

ENSEMBL:ENSG00000115839 RAB3GAP1

HGNC:17063 RAB3GAP1

Monarch:22930 RAB3GAP1

NCBI Gene:22930 RAB3GAP1

OMIM:602536 RAB3GAP1

UCSC:Q15042 RAB3GAP1

Reference Transcript

Other Identifiers

11721105_s_at

11721106_a_at

11750261_a_at

11761872_at

16885939

212932_PM_at

212932_at

213530_PM_at

213530_at

213531_PM_s_at

213531_s_at

22930

239527_PM_at

239527_at

242014_PM_at

242014_at

2507274

2507276

2507277

2507278

2507279

2507280

2507281

2507282

2507293

2507295

2507296

2507303

2507304

2507305

2507306

2507307

2507308

2507309

2507310

2507311

2507312

2507313

2507315

2507317

2507321

2507322

2507323

2507324

2507328

2507329

2507330

2507331

2507332

2507333

2507335

2507336

2507337

2507338

2507339

2507340

2507341

2507342

2507343

2507344

2507345

2507363

2507364

33417_at

33418_at

43749_at

67689_at

8045398

82678_at

A_14_P130570

A_23_P50942

A_24_P937965

A_33_P3280739

D31886_at

GE63067

GE666785

GE788036

GO:0005085

GO:0005096

GO:0005515

GO:0005737

GO:0005783

GO:0005789

GO:0005794

GO:0005811

GO:0005829

GO:0007420

GO:0021854

GO:0031267

GO:0032991

GO:0034389

GO:0043010

GO:0043087

GO:0043226

GO:0043547

GO:0048172

GO:0048856

GO:0060079

GO:0060325

GO:0061646

GO:0070062

GO:0071782

GO:0097051

GO:0098772

GO:0098794

GO:1903061

GO:1903233

GO:1903373

GO:2000786

HMNXSV003009343

HMNXSV003051009

Hs.167549.0.A1_3p_at

Hs.167549.0.A1_3p_x_at

Hs.187534.0.A1_3p_at

Hs.227881.0.S1_3p_at

Hs.309509.0.A1_3p_at

ILMN_1739876

PH_hs_0015735

TC02000879.hg

Participates

as a component of

RAB3GAP1:RAB3GAP2 [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

RAB3GAP1 [cytosol]

Inferred To

Rab3gap1 [endoplasmic reticulum membrane] (Mus musculus)

Rab3gap1 [endoplasmic reticulum membrane] (Rattus norvegicus)

Rab3GAP1 [endoplasmic reticulum membrane] (Drosophila melanogaster)

RAB3GAP1 [endoplasmic reticulum membrane] (Bos taurus)

RAB3GAP1 [endoplasmic reticulum membrane] (Canis familiaris)

RAB3GAP1 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

RAB3GAP1 [endoplasmic reticulum membrane] (Gallus gallus)

RAB3GAP1 [endoplasmic reticulum membrane] (Sus scrofa)

rbg-1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENSP00000411418, ENST00000442034, ENST00000264158, ENSP00000264158

OpenTargets

ENSG00000115839

HPA

ENSG00000115839-RAB3GAP1

PRO

Q15042

Pharos - Targets

Q15042

GlyGen

Q15042

Orphanet

RAB3GAP1

HMDB Protein

HMDBP08528

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:A6NED2 RCCD1	2	3OHR141-RCCD1 [cytosol] (R-HSA-9629871) RCCD1 [cytosol] (R-HSA-9629873)	0.527	2
UniProt:P09917 ALOX5	6	p-S272-ALOX5 [nuclear envelope] (R-HSA-2318765) ALOX5 [cytosol] (R-HSA-429010) ALOX5 [secretory granule lumen] (R-HSA-6801306) ALOX5 [extracellular region] (R-HSA-6806468) ALOX5 [ficolin-1-rich granule lumen] (R-HSA-6801302) p-S272-ALOX5 [cytosol] (R-HSA-265276)	0.527	2
UniProt:P15056 BRAF	20	p-S,T-BRAF [cytosol] (R-HSA-169856) BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620)	0.527	2
UniProt:Q7KYR7 BTN2A1	1	BTN2A1 [plasma membrane] (R-HSA-8851994)	0.527	2