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ATP6V1G3 [cytosol]
Stable Identifier
R-HSA-912589
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
RRAGA,B exchanges GDP for GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
RRAGA,B hydrolyzes GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
RRAGC,D exchanges GTP for GDP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
RRAGC,D hydrolyzes GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
mTORC1 binds RHEB:GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator [lysosomal membrane] (Homo sapiens)
v-ATPase [lysosomal membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
Intraphagosomal pH is lowered to 5 by V-ATPase (Homo sapiens)
V-ATPase [phagocytic vesicle membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor recycling (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
Endosome acidification (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
Iron uptake and transport (Homo sapiens)
Transferrin endocytosis and recycling (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
Acidification of Tf:TfR1 containing endosome (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase [endosome membrane] (Homo sapiens)
ATP6V1 [cytosol] (Homo sapiens)
ATP6V1G dimer [cytosol] (Homo sapiens)
ATP6V1G [cytosol] (Homo sapiens)
ATP6V1G3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96LB4 ATP6V1G3
Gene Names
ATP6V1G3, ATP6G3
Chain
chain:1-118
Reference Genes
BioGPS Gene:127124 ATP6V1G3
COSMIC (genes):ATP6V1G3 ATP6V1G3
CTD Gene:127124 ATP6V1G3
dbSNP Gene:127124 ATP6V1G3
ENSEMBL:ENSG00000151418 ATP6V1G3
ENSEMBL_homo_sapiens_GENE:ENSG00000151418.12 ATP6V1G3
ENSEMBL_homo_sapiens_GENE:ENSG00000263014.5 ATP6V1G3
HGNC:18265 ATP6V1G3
KEGG Gene (Homo sapiens):127124 ATP6V1G3
Monarch:127124 ATP6V1G3
NCBI Gene:127124 ATP6V1G3
OMIM:618071 ATP6V1G3
UCSC:Q96LB4 ATP6V1G3
Reference Transcript
RefSeq:XM_011509186.2 ATP6V1G3
RefSeq:NM_133262.2 ATP6V1G3
RefSeq:NM_001320218.1 ATP6V1G3
RefSeq:XM_006711163.3 ATP6V1G3
RefSeq:XM_011509187.2 ATP6V1G3
RefSeq:NM_133326.1 ATP6V1G3
Other Identifiers
11753935_a_at
127124
16697637
230565_PM_at
230565_at
2449923
2449924
2449925
2449926
2449927
2449928
2449930
2449931
2449932
2449933
7923164
90107_at
A_23_P23797
GE496983
GO:0005215
GO:0005515
GO:0005773
GO:0005829
GO:0005886
GO:0006811
GO:0016471
GO:0043226
GO:0046961
GO:0051117
GO:0055085
GO:0140657
GO:1902600
HMNXSV003016707
Hs.127743.0.A1_3p_at
ILMN_1726273
ILMN_2371001
TC01003667.hg
Participates
as a member of
ATP6V1G [cytosol] (Homo sapiens)
Inferred To
ATP6V1G3 [cytosol]
(Bos taurus)
ATP6V1G3 [cytosol]
(Canis familiaris)
ATP6V1G3 [cytosol]
(Gallus gallus)
ATP6V1G3 [cytosol]
(Sus scrofa)
wu:fa12a02 [cytosol]
(Danio rerio)
atp6v1g3 [cytosol]
(Xenopus tropicalis)
vma10 [cytosol]
(Schizosaccharomyces pombe)
Atp6v1g3 [cytosol]
(Mus musculus)
Atp6v1g3 [cytosol]
(Rattus norvegicus)
vha-10 [cytosol]
(Caenorhabditis elegans)
Vha13 [cytosol]
(Drosophila melanogaster)
VMA10 [cytosol]
(Saccharomyces cerevisiae)
atp6v1g [cytosol]
(Dictyostelium discoideum)
ATP6V1G2 [cytosol]
(Plasmodium falciparum)
Cross References
RefSeq
XP_011507489.1
,
XP_011507488.1
,
NP_001307147.1
,
NP_579872.1
,
NP_573569.1
,
XP_006711226.1
Guide to Pharmacology - Targets
821
OpenTargets
ENSG00000151418
HPA
ENSG00000151418-ATP6V1G3
GeneCards
Q96LB4
Ensembl
ENST00000281087
,
ENST00000575971
,
ENSP00000461228
,
ENSP00000461329
,
ENSG00000151418
,
ENSG00000263014
,
ENST00000489986
,
ENST00000573121
,
ENST00000367381
,
ENSP00000417171
,
ENST00000367382
,
ENSP00000281087
,
ENSP00000309574
,
ENSP00000356351
,
ENSP00000461616
,
ENSP00000356352
,
ENST00000309309
,
ENST00000571439
PRO
Q96LB4
Pharos - Targets
Q96LB4
HMDB Protein
HMDBP01166
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