Reactome | Atp6v1g3 [cytosol]

Atp6v1g3 [cytosol]

Stable Identifier

R-RNO-912589

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

ATP6V1G3, D3ZTZ4

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Rattus norvegicus)

- Cellular responses to stress (Rattus norvegicus)
  - Cellular response to starvation (Rattus norvegicus)
    - Amino acids regulate mTORC1 (Rattus norvegicus)
      - RRAGA,B exchanges GDP for GTP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - RRAGA,B hydrolyzes GTP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - RRAGC,D exchanges GTP for GDP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - RRAGC,D hydrolyzes GTP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - mTORC1 binds RHEB:GTP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)

Immune System (Rattus norvegicus)

- Innate Immune System (Rattus norvegicus)
  - ROS and RNS production in phagocytes (Rattus norvegicus)
    - Intraphagosomal pH is lowered to 5 by V-ATPase (Rattus norvegicus)
      - V-ATPase [phagocytic vesicle membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
  - Signaling by Insulin receptor (Rattus norvegicus)
    - Insulin receptor recycling (Rattus norvegicus)
      - ATP6AP1 binds V-ATPase (Rattus norvegicus)
        
        V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Rattus norvegicus)
        
        V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - Endosome acidification (Rattus norvegicus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Rattus norvegicus)
        
        V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)

Transport of small molecules (Rattus norvegicus)

- Ion channel transport (Rattus norvegicus)
  - ATP6AP1 binds V-ATPase (Rattus norvegicus)
    - V-ATPase [endosome membrane] (Rattus norvegicus)
      - ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
    - V-ATPase:ATP6AP1 [endosome membrane] (Rattus norvegicus)
      - V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
- Iron uptake and transport (Rattus norvegicus)
  - Transferrin endocytosis and recycling (Rattus norvegicus)
    - ATP6AP1 binds V-ATPase (Rattus norvegicus)
      - V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
      - V-ATPase:ATP6AP1 [endosome membrane] (Rattus norvegicus)
        
        V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)
    - Acidification of Tf:TfR1 containing endosome (Rattus norvegicus)
      - V-ATPase:ATP6AP1 [endosome membrane] (Rattus norvegicus)
        
        V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        ATP6V1G dimer [cytosol] (Rattus norvegicus)
        
        ATP6V1G [cytosol] (Rattus norvegicus)
        
        Atp6v1g3 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZTZ4

Gene Names

Atp6v1g3

Reference Genes

BioGPS Gene:289407 Atp6v1g3

ENSEMBL:ENSRNOG00000022480

ENSEMBL:ENSRNOG00000022480.5 Atp6v1g3

Monarch:289407 Atp6v1g3

NCBI Gene:289407 Atp6v1g3

Reference Transcript

RefSeq:XM_017598761.1 Atp6v1g3

Other Identifiers

10764369

1383893_at

1386166_at

17680562

289407

5733588

6296702

6386642

6456703

6623251

A_44_P114320

A_64_P113094

GE1139550

GO:0005215

GO:0005773

GO:0005829

GO:0005886

GO:0016471

GO:0043226

GO:0046961

GO:0051117

GO:0055085

GO:0140657

GO:1902600

ILMN_1365854

PH_rn_0011847

rc_AA892881_at

rc_AI232844_at

Participates

as a member of

ATP6V1G [cytosol] (Rattus norvegicus)

Inferred From

ATP6V1G3 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_017454250.1

Ensembl

ENSRNOP00000032126, ENSRNOT00000029679, ENSRNOG00000022480

RGD

1304635

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