Reactome | ATP6V1G3 [cytosol]

ATP6V1G3 [cytosol]

Stable Identifier

R-GGA-912589

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

ATP6V1G3, A0A1D5P6L6

Locations in the PathwayBrowser

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Cellular responses to stimuli (Gallus gallus)

- Cellular responses to stress (Gallus gallus)
  - Cellular response to starvation (Gallus gallus)
    - Amino acids regulate mTORC1 (Gallus gallus)
      - RRAGA,B exchanges GDP for GTP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
      - RRAGA,B hydrolyzes GTP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
      - RRAGC,D exchanges GTP for GDP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
      - RRAGC,D hydrolyzes GTP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
      - mTORC1 binds RHEB:GTP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)

Immune System (Gallus gallus)

- Innate Immune System (Gallus gallus)
  - ROS and RNS production in phagocytes (Gallus gallus)
    - Intraphagosomal pH is lowered to 5 by V-ATPase (Gallus gallus)
      - V-ATPase [phagocytic vesicle membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Signaling by Receptor Tyrosine Kinases (Gallus gallus)
  - Signaling by Insulin receptor (Gallus gallus)
    - Insulin receptor recycling (Gallus gallus)
      - Endosome acidification (Gallus gallus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Gallus gallus)
        
        V-ATPase [endosome membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)

Transport of small molecules (Gallus gallus)

- Iron uptake and transport (Gallus gallus)
  - Transferrin endocytosis and recycling (Gallus gallus)
    - Acidification of Tf:TfR1 containing endosome (Gallus gallus)
      - V-ATPase:ATP6AP1 [endosome membrane] (Gallus gallus)
        
        V-ATPase [endosome membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1G dimer [cytosol] (Gallus gallus)
        
        ATP6V1G [cytosol] (Gallus gallus)
        
        ATP6V1G3 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A1D5P6L6

Gene Names

ATP6V1G3

Reference Genes

BioGPS Gene:424349 ATP6V1G3

ENSEMBL:ENSGALG00000002207

ENSEMBL:ENSGALG00010012371.1 ATP6V1G3

KEGG Gene (Gallus gallus):424349 ATP6V1G3

Monarch:424349 ATP6V1G3

NCBI Gene:424349 ATP6V1G3

Reference Transcript

RefSeq:XM_422192.3 ATP6V1G3

Other Identifiers

424349

GO:0005215

GO:0005773

GO:0005829

GO:0005886

GO:0006811

GO:0016471

GO:0043226

GO:0046961

GO:0051117

GO:0055085

GO:0140657

GO:1902600

GT_A_87_P078276

Gga.10666.1.S1_at

Participates

as a member of

ATP6V1G [cytosol] (Gallus gallus)

Inferred From

ATP6V1G3 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_422192.1

OpenTargets

ENSG00000151418

Ensembl

ENSGALT00010029617, ENSGALP00010017231, ENSGALG00010012371

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