Reactome | atp6v1g3 [cytosol]

atp6v1g3 [cytosol]

Stable Identifier

R-XTR-912589

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

ATP6V1G3, A4QNE9

Locations in the PathwayBrowser

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Cellular responses to stimuli (Xenopus tropicalis)

- Cellular responses to stress (Xenopus tropicalis)
  - Cellular response to starvation (Xenopus tropicalis)
    - Amino acids regulate mTORC1 (Xenopus tropicalis)
      - RRAGA,B exchanges GDP for GTP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
      - RRAGA,B hydrolyzes GTP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
      - RRAGC,D exchanges GTP for GDP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
      - RRAGC,D hydrolyzes GTP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
      - mTORC1 binds RHEB:GTP (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase:Ragulator [lysosomal membrane] (Xenopus tropicalis)
        
        v-ATPase [lysosomal membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)

Immune System (Xenopus tropicalis)

- Innate Immune System (Xenopus tropicalis)
  - ROS and RNS production in phagocytes (Xenopus tropicalis)
    - Intraphagosomal pH is lowered to 5 by V-ATPase (Xenopus tropicalis)
      - V-ATPase [phagocytic vesicle membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
  - Signaling by Insulin receptor (Xenopus tropicalis)
    - Insulin receptor recycling (Xenopus tropicalis)
      - ATP6AP1 binds V-ATPase (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
      - Endosome acidification (Xenopus tropicalis)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)

Transport of small molecules (Xenopus tropicalis)

- Ion channel transport (Xenopus tropicalis)
  - ATP6AP1 binds V-ATPase (Xenopus tropicalis)
    - V-ATPase [endosome membrane] (Xenopus tropicalis)
      - ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
    - V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
      - V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
- Iron uptake and transport (Xenopus tropicalis)
  - Transferrin endocytosis and recycling (Xenopus tropicalis)
    - ATP6AP1 binds V-ATPase (Xenopus tropicalis)
      - V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
      - V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)
    - Acidification of Tf:TfR1 containing endosome (Xenopus tropicalis)
      - V-ATPase:ATP6AP1 [endosome membrane] (Xenopus tropicalis)
        
        V-ATPase [endosome membrane] (Xenopus tropicalis)
        
        ATP6V1 [cytosol] (Xenopus tropicalis)
        
        ATP6V1G dimer [cytosol] (Xenopus tropicalis)
        
        ATP6V1G [cytosol] (Xenopus tropicalis)
        
        atp6v1g3 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A4QNE9

Gene Names

atp6v1g3

Reference Genes

BioGPS Gene:100125150 atp6v1g3

ENSEMBL:ENSXETG00000009966

KEGG Gene (Xenopus tropicalis):100125150 atp6v1g3

Monarch:100125150 atp6v1g3

NCBI Gene:100125150 atp6v1g3

Reference Transcript

RefSeq:NM_001103047.1 atp6v1g3

Other Identifiers

100125150

GO:0005215

GO:0005773

GO:0006811

GO:0016471

GO:0043226

GO:0046961

GO:0055085

GO:0140657

GO:1902600

Participates

as a member of

ATP6V1G [cytosol] (Xenopus tropicalis)

Inferred From

ATP6V1G3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001096517.1

Ensembl

ENSXETT00000021955, ENSXETG00000009966, ENSXETP00000021955

Xenbase

XB-GENE-949366

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