Reactome | PEX5 isoform L [cytosol]

PEX5 isoform L [cytosol]

Stable Identifier

R-HSA-9033103

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Peroxisomal targeting signal 1 receptor, PEX5_HUMAN

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External Reference Information

External Reference

UniProt:P50542-1 PEX5

Gene Names

PEX5, PXR1

Participates

as an output of

USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Homo sapiens)

as an input of

PEX5L binds PEX7:Cargo protein (Homo sapiens)

as a component of

PEX5L:PEX7:Cargo protein [cytosol] (Homo sapiens)

as a member of

PEX5S,L [cytosol] (Homo sapiens)

Other forms of this molecule

PEX5 isoform L [peroxisomal membrane]

Ub-C11-PEX5L [peroxisomal membrane]

Ub-C11-PEX5L [cytosol]

Inferred To

Pex5 [cytosol] (Drosophila melanogaster)

Pex5 [cytosol] (Mus musculus)

Pex5 [cytosol] (Rattus norvegicus)

prx-5 [cytosol] (Caenorhabditis elegans)

PEX5 [cytosol] (Bos taurus)

PEX5 [cytosol] (Canis familiaris)

PEX5 [cytosol] (Saccharomyces cerevisiae)

PEX5 [cytosol] (Sus scrofa)

PEX5 isoform L [cytosol] (Gallus gallus)

pex5 [cytosol] (Dictyostelium discoideum)

pex5 [cytosol] (Schizosaccharomyces pombe)

pex5 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

XP_016875243.1, XP_016875241.1, XP_016875242.1, XP_016875244.1, XP_016875237.1, XP_011519102.1, XP_011519100.1, NP_001124498.1, NP_001124496.1, XP_011519101.1, NP_001124497.1, NP_001124495.1, NP_001287718.1, XP_011519097.1, NP_000310.2, XP_016875238.1, XP_016875239.1, XP_011519099.1

OpenTargets

ENSG00000139197

ENSEMBL

ENSP00000499823, ENSG00000139197, ENST00000455147, ENSP00000502374, ENSP00000500043, ENSP00000500230, ENST00000420616, ENSP00000410159, ENSP00000500696, ENSP00000266564, ENSP00000266563, ENSP00000500509, ENST00000266563, ENSG00000288217, ENSP00000400647, ENST00000671993, ENST00000672694, ENST00000672541, ENST00000672242, ENST00000675855, ENST00000434354, ENST00000672776, ENST00000266564, ENSP00000407401

HPA

ENSG00000139197-PEX5

GeneCards

PEX5

PRO

P50542

Pharos - Targets

P50542

Orphanet

PEX5

HMDB Protein

HMDBP14577

PDB

2C0L, 2J9Q, 2C0M, 1FCH, 4KXK, 9GAG, 4BXU, 7Z0K, 4KYO, 3R9A, 2W84

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75381 PEX14	2	PEX14 [cytosol] (R-HSA-9603806) PEX14 [peroxisomal membrane] (R-HSA-9033101)	0.807	13
UniProt:O00623 PEX12	2	PEX12 [cytosol] (R-HSA-9603782) PEX12 [peroxisomal membrane] (R-HSA-8953911)	0.683	4
UniProt:Q6IMN6 CAPR2			0.556	3
UniProt:P06703 S10A6			0.556	3
UniProt:O14734 ACOT8	2	ACOT8 [cytosol] (R-HSA-9033134) ACOT8 [peroxisomal matrix] (R-HSA-193426)	0.556	3
UniProt:Q68DY9 ZNF772	1	ZNF772 [nucleoplasm] (R-HSA-3110231)	0.556	3
UniProt:Q6IPH7 Q6IPH7			0.556	3
UniProt:Q75MR5 Q75MR5			0.556	3
UniProt:Q8N5N8 Q8N5N8			0.556	3
UniProt:A8K3Q9 A8K3Q9			0.556	3
UniProt:Q6NSB6 Q6NSB6			0.556	3
UniProt:Q49A88 CCD14			0.556	3
UniProt:Q9NZ81 PRR13			0.556	3
UniProt:Q8WTR4 GDPD5	1	GDPD5 [endoplasmic reticulum membrane] (R-HSA-6814136)	0.556	3
UniProt:EP400NL H9KV84			0.556	3
UniProt:P07195 LDHB	1	LDHB [cytosol] (R-HSA-70503)	0.556	3
UniProt:Q9BSI4 TINF2	1	TINF2 [nucleoplasm] (R-HSA-174883)	0.508	2

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