Reactome | PEX5 isoform L [cytosol]

PEX5 isoform L [cytosol]

Stable Identifier

R-HSA-9033103

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Peroxisomal targeting signal 1 receptor, PEX5_HUMAN

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External Reference Information

External Reference

UniProt:P50542-1 PEX5

Gene Names

PEX5, PXR1

Other Identifiers

0002100369

11719618_a_at

11741493_a_at

16747770

203244_at

215481_s_at

2465572

2465576

3403300

3403301

3403302

3403303

3403305

3403306

3403307

3403309

3403310

3403311

3403316

3403317

3403319

3403321

3403322

3403323

3403324

3403325

3403326

3403327

3403328

3403329

3403330

3403332

40151_s_at

40152_r_at

5830

7953651

A_23_P48246

A_24_P372932

GE60411

GO:0000268

GO:0003674

GO:0005052

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005777

GO:0005778

GO:0005794

GO:0005829

GO:0006464

GO:0006605

GO:0006625

GO:0006810

GO:0008150

GO:0015031

GO:0016020

GO:0016558

GO:0016560

GO:0016567

GO:0019899

GO:0022607

GO:0031267

GO:0031333

GO:0032991

GO:0033328

GO:0043226

GO:0045046

GO:0047485

GO:0055085

GO:0065003

GO:0140311

Hs.158084.1.A1_3p_a_at

ILMN_1660232

PH_hs_0029792

TC12000109.hg

U35407_at

Z48054_at

g4506346_3p_at

Participant Of

output

USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin

input

PEX5L binds PEX7:Cargo protein

hasComponent

PEX5L:PEX7:Cargo protein [cytosol]

hasMember

PEX5S,L [cytosol]

Other forms of this molecule

Ub-C11-PEX5L [cytosol]

Ub-C11-PEX5L [peroxisomal membrane]

PEX5 isoform L [peroxisomal membrane]

Inferred To

Pex5 [cytosol] (Drosophila melanogaster)

Pex5 [cytosol] (Mus musculus)

Pex5 [cytosol] (Rattus norvegicus)

prx-5 [cytosol] (Caenorhabditis elegans)

PEX5 [cytosol] (Canis familiaris)

PEX5 [cytosol] (Saccharomyces cerevisiae)

PEX5 [cytosol] (Sus scrofa)

PEX5 isoform L [cytosol] (Gallus gallus)

PEX5 isoform L [cytosol] (Xenopus tropicalis)

pex5 [cytosol] (Danio rerio)

pex5 [cytosol] (Dictyostelium discoideum)

pex5 [cytosol] (Schizosaccharomyces pombe)

Cross References

RefSeq

XP_011519097.1, XP_011519100.1, NP_001124496.1, NP_000310.2, NP_001124497.1, XP_011519099.1, NP_001287718.1, XP_016875238.1, NP_001124498.1, NP_001124495.1, XP_011519101.1, XP_016875237.1, XP_011519102.1

OpenTargets

ENSG00000139197

HPA

ENSG00000139197-PEX5

GeneCards

P50542

Ensembl

ENST00000671993, ENST00000434354, ENST00000672776, ENST00000672242, ENST00000672694, ENST00000672541, ENSP00000407401, ENSP00000500509, ENSG00000139197, ENSG00000288217, ENSP00000499823, ENSP00000400647, ENST00000420616, ENSP00000500230, ENSP00000500043, ENSP00000410159, ENST00000455147, ENST00000266564, ENSP00000500696, ENST00000266563, ENSP00000266564, ENSP00000266563

PRO

P50542

Orphanet

16646

PDB

4KYO, 2W84, 1FCH, 2C0M, 2C0L, 3R9A, 4BXU, 2J9Q, 4KXK

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75381 PEX14	2	PEX14 [peroxisomal membrane] (R-HSA-9033101) PEX14 [cytosol] (R-HSA-9603806)	0.807	13
UniProt:O00623 PEX12	2	PEX12 [peroxisomal membrane] (R-HSA-8953911) PEX12 [cytosol] (R-HSA-9603782)	0.683	4
UniProt:P07195 LDHB	1	LDHB [cytosol] (R-HSA-70503)	0.556	3
UniProt:EP400NL H9KV84			0.556	3
UniProt:Q9NZ81 PRR13			0.556	3
UniProt:Q49A88 CCD14			0.556	3
UniProt:Q6NSB6 Q6NSB6			0.556	3
UniProt:A8K3Q9 A8K3Q9			0.556	3
UniProt:Q8N5N8 Q8N5N8			0.556	3
UniProt:Q75MR5 Q75MR5			0.556	3
UniProt:Q6IPH7 Q6IPH7			0.556	3
UniProt:Q68DY9 ZNF772	1	ZNF772 [nucleoplasm] (R-HSA-3110231)	0.556	3
UniProt:P06703 S10A6			0.556	3
UniProt:Q6IMN6 CAPR2			0.556	3
UniProt:O14734 ACOT8	2	ACOT8 [peroxisomal matrix] (R-HSA-193426) ACOT8 [cytosol] (R-HSA-9033134)	0.556	3
UniProt:Q8WTR4 GDPD5	1	GDPD5 [endoplasmic reticulum membrane] (R-HSA-6814136)	0.556	3
UniProt:Q9BSI4 TINF2	1	TINF2 [nucleoplasm] (R-HSA-174883)	0.508	2

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