Reactome | PEX5 isoform L [peroxisomal membrane]

PEX5 isoform L [peroxisomal membrane]

Stable Identifier

R-HSA-9033489

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

peroxisomal membrane

Synonyms

Peroxisomal targeting signal 1 receptor, PEX5_HUMAN

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External Reference Information

External Reference

UniProt:P50542-1 PEX5

Gene Names

PEX5, PXR1

Participates

as a component of

PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)

as a member of

PEX5S,L [peroxisomal membrane] (Homo sapiens)

Other forms of this molecule

Ub-C11-PEX5L [peroxisomal membrane]

PEX5 isoform L [cytosol]

Ub-C11-PEX5L [cytosol]

Inferred To

Ghost homologue of PEX5 isoform L [peroxisomal membrane] (Danio rerio)

pex5 [peroxisomal membrane] (Dictyostelium discoideum)

pex5 [peroxisomal membrane] (Schizosaccharomyces pombe)

pex5 [peroxisomal membrane] (Xenopus tropicalis)

Pex5 [peroxisomal membrane] (Drosophila melanogaster)

Pex5 [peroxisomal membrane] (Mus musculus)

Pex5 [peroxisomal membrane] (Rattus norvegicus)

PEX5 [peroxisomal membrane] (Bos taurus)

PEX5 [peroxisomal membrane] (Canis familiaris)

PEX5 [peroxisomal membrane] (Gallus gallus)

PEX5 [peroxisomal membrane] (Saccharomyces cerevisiae)

PEX5 [peroxisomal membrane] (Sus scrofa)

Cross References

RefSeq

NP_001361574.1, NP_001361575.1, XP_047285221.1, XP_016875237.1, NP_001338062.1, NP_001338061.1, NP_001338060.1, XP_054188513.1, NP_001338066.2, XP_054188515.1, XP_047285216.1, XP_011519097.1, NP_001338055.1, NP_001338057.1, NP_001338059.1, NP_001338053.1, NP_001338056.1, NP_001338063.1, NP_001124496.1, NP_001124498.1, NP_001287718.2, NP_001124495.1, NP_001124497.1, XP_011519102.1, XP_011519100.1, XP_047285223.1, XP_016875238.1, XP_016875239.1, XP_054188507.1, XP_054188508.1, XP_016875243.1, XP_016875244.1, NP_001361576.1, XP_054188509.1, NP_001361577.1, XP_016875241.1, XP_011519099.1, XP_016875242.1, XP_047285218.1, NP_000310.2, XP_054188510.1, XP_011519101.1

OpenTargets

ENSG00000139197

ENSEMBL

ENST00000434354, ENST00000672242, ENST00000672541, ENST00000675855, ENST00000672694, ENST00000672776, ENSG00000288217, ENST00000266564, ENST00000671993, ENST00000455147, ENSP00000407401, ENST00000266563, ENSP00000499823, ENSP00000410159, ENSP00000500509, ENSG00000139197, ENST00000420616, ENSP00000500696, ENSP00000500230, ENSP00000500043, ENSP00000400647, ENSP00000266563, ENSP00000502374, ENSP00000266564

HPA

ENSG00000139197-PEX5

GeneCards

PEX5

PRO

P50542

Pharos - Targets

P50542

Orphanet

PEX5

HMDB Protein

HMDBP14577

PDB

4KYO, 3R9A, 7Z0K, 4BXU, 2C0M, 1FCH, 9GAG, 2W84, 4KXK, 2J9Q, 2C0L

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75381 PEX14	2	PEX14 [cytosol] (R-HSA-9603806) PEX14 [peroxisomal membrane] (R-HSA-9033101)	0.807	13
UniProt:O00623 PEX12	2	PEX12 [cytosol] (R-HSA-9603782) PEX12 [peroxisomal membrane] (R-HSA-8953911)	0.683	4
UniProt:Q6IMN6 CAPR2			0.556	3
UniProt:P06703 S10A6			0.556	3
UniProt:O14734 ACOT8	2	ACOT8 [cytosol] (R-HSA-9033134) ACOT8 [peroxisomal matrix] (R-HSA-193426)	0.556	3
UniProt:Q68DY9 ZNF772	1	ZNF772 [nucleoplasm] (R-HSA-3110231)	0.556	3
UniProt:Q6IPH7 Q6IPH7			0.556	3
UniProt:Q75MR5 Q75MR5			0.556	3
UniProt:Q8N5N8 Q8N5N8			0.556	3
UniProt:A8K3Q9 A8K3Q9			0.556	3
UniProt:Q6NSB6 Q6NSB6			0.556	3
UniProt:Q49A88 CCD14			0.556	3
UniProt:Q9NZ81 PRR13			0.556	3
UniProt:Q8WTR4 GDPD5	1	GDPD5 [endoplasmic reticulum membrane] (R-HSA-6814136)	0.556	3
UniProt:EP400NL H9KV84			0.556	3
UniProt:P07195 LDHB	1	LDHB [cytosol] (R-HSA-70503)	0.556	3
UniProt:Q9BSI4 TINF2	1	TINF2 [nucleoplasm] (R-HSA-174883)	0.508	2

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