Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PEX5 isoform L [peroxisomal membrane]
Stable Identifier
R-HSA-9033489
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal membrane
Synonyms
Peroxisomal targeting signal 1 receptor, PEX5_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Homo sapiens)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Homo sapiens)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Homo sapiens)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Homo sapiens)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Homo sapiens)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Homo sapiens)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Homo sapiens)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Homo sapiens)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Homo sapiens)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Homo sapiens)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Homo sapiens)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Homo sapiens)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L [peroxisomal membrane] (Homo sapiens)
PEX5 isoform L [peroxisomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P50542-1 PEX5
Gene Names
PEX5, PXR1
Other Identifiers
11719618_a_at
11741493_a_at
16747770
203244_PM_at
203244_at
215481_PM_s_at
215481_s_at
2465572
2465576
3403300
3403301
3403302
3403303
3403305
3403306
3403307
3403309
3403310
3403311
3403316
3403317
3403319
3403321
3403322
3403323
3403324
3403325
3403326
3403327
3403328
3403329
3403330
3403332
40151_s_at
40152_r_at
5830
7953651
A_23_P48246
A_24_P372932
GE60411
GO:0000038
GO:0000268
GO:0000425
GO:0001764
GO:0005052
GO:0005515
GO:0005737
GO:0005739
GO:0005777
GO:0005778
GO:0005782
GO:0005794
GO:0005829
GO:0006625
GO:0006629
GO:0006635
GO:0006886
GO:0006914
GO:0007005
GO:0007006
GO:0007029
GO:0007031
GO:0015031
GO:0016020
GO:0016558
GO:0016560
GO:0016561
GO:0016562
GO:0019899
GO:0021795
GO:0021895
GO:0030154
GO:0031267
GO:0031333
GO:0032991
GO:0033328
GO:0034614
GO:0040018
GO:0043226
GO:0044255
GO:0044721
GO:0045046
GO:0048468
GO:0048856
GO:0048870
GO:0050877
GO:0050905
GO:0051262
GO:0055085
GO:0061024
GO:0065003
GO:0140104
GO:0140597
HMNXSV003030185
HMNXSV003058153
Hs.158084.1.A1_3p_a_at
ILMN_1660232
PH_hs_0029792
TC12000109.hg
U35407_at
Z48054_at
g4506346_3p_at
Participates
as a component of
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
as a member of
PEX5S,L [peroxisomal membrane] (Homo sapiens)
Other forms of this molecule
Ub-C11-PEX5L [cytosol]
PEX5 isoform L [cytosol]
Ub-C11-PEX5L [peroxisomal membrane]
Inferred To
PEX5 isoform L [peroxisomal membrane]
(Gallus gallus)
pex5 [peroxisomal membrane]
(Dictyostelium discoideum)
pex5 [peroxisomal membrane]
(Schizosaccharomyces pombe)
pex5 [peroxisomal membrane]
(Xenopus tropicalis)
Pex5 [peroxisomal membrane]
(Drosophila melanogaster)
Pex5 [peroxisomal membrane]
(Mus musculus)
Pex5 [peroxisomal membrane]
(Rattus norvegicus)
prx-5 [peroxisomal membrane]
(Caenorhabditis elegans)
PEX5 [peroxisomal membrane]
(Bos taurus)
PEX5 [peroxisomal membrane]
(Canis familiaris)
PEX5 [peroxisomal membrane]
(Saccharomyces cerevisiae)
PEX5 [peroxisomal membrane]
(Sus scrofa)
Cross References
RefSeq
XP_011519101.1
,
XP_016875238.1
,
XP_011519097.1
,
XP_016875243.1
,
NP_001124495.1
,
XP_011519102.1
,
XP_016875244.1
,
XP_016875241.1
,
NP_001124498.1
,
NP_001124497.1
,
NP_001287718.1
,
XP_016875239.1
,
XP_016875242.1
,
XP_011519099.1
,
XP_011519100.1
,
NP_001124496.1
,
NP_000310.2
,
XP_016875237.1
OpenTargets
ENSG00000139197
GeneCards
P50542
HPA
ENSG00000139197-PEX5
Ensembl
ENSP00000407401
,
ENST00000420616
,
ENSP00000499823
,
ENSP00000266563
,
ENSP00000266564
,
ENSP00000500509
,
ENSP00000502374
,
ENSP00000500043
,
ENSP00000500230
,
ENSG00000288217
,
ENST00000266564
,
ENST00000266563
,
ENSP00000400647
,
ENSP00000500696
,
ENST00000675855
,
ENST00000455147
,
ENST00000672541
,
ENST00000672694
,
ENSG00000139197
,
ENST00000672776
,
ENST00000672242
,
ENSP00000410159
,
ENST00000671993
,
ENST00000434354
PRO
P50542
Pharos - Targets
P50542
Orphanet
16646
PDB
2C0M
,
4KYO
,
7Z0K
,
4KXK
,
4BXU
,
2W84
,
2C0L
,
2J9Q
,
1FCH
,
3R9A
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75381 PEX14
2
PEX14 [cytosol]
(R-HSA-9603806)
PEX14 [peroxisomal membrane]
(R-HSA-9033101)
0.807
13
UniProt:O00623 PEX12
2
PEX12 [cytosol]
(R-HSA-9603782)
PEX12 [peroxisomal membrane]
(R-HSA-8953911)
0.683
4
UniProt:P07195 LDHB
1
LDHB [cytosol]
(R-HSA-70503)
0.556
3
UniProt:EP400NL H9KV84
0.556
3
UniProt:Q9NZ81 PRR13
0.556
3
UniProt:Q49A88 CCD14
0.556
3
UniProt:Q6NSB6 Q6NSB6
0.556
3
UniProt:A8K3Q9 A8K3Q9
0.556
3
UniProt:Q8N5N8 Q8N5N8
0.556
3
UniProt:Q75MR5 Q75MR5
0.556
3
UniProt:Q6IPH7 Q6IPH7
0.556
3
UniProt:Q68DY9 ZNF772
1
ZNF772 [nucleoplasm]
(R-HSA-3110231)
0.556
3
UniProt:P06703 S10A6
0.556
3
UniProt:Q6IMN6 CAPR2
0.556
3
UniProt:O14734 ACOT8
2
ACOT8 [cytosol]
(R-HSA-9033134)
ACOT8 [peroxisomal matrix]
(R-HSA-193426)
0.556
3
UniProt:Q8WTR4 GDPD5
1
GDPD5 [endoplasmic reticulum membrane]
(R-HSA-6814136)
0.556
3
UniProt:Q9BSI4 TINF2
1
TINF2 [nucleoplasm]
(R-HSA-174883)
0.508
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text