Reactome | MIA3 [endoplasmic reticulum lumen]

MIA3 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8956743

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Melanoma inhibitory activity protein 3, MIA3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5JRA6 MIA3

Gene Names

MIA3, KIAA0268, TANGO, TANGO1, UNQ6077/PRO20088

Chain

signal peptide:1-22, chain:23-1907

Reference Genes

COSMIC (genes):MIA3 MIA3

dbSNP Gene:375056 MIA3

ENSEMBL:ENSG00000154305 MIA3

Participates

as a member of

FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

MIA3 [endoplasmic reticulum membrane]

p-MIA3 [endoplasmic reticulum lumen]

Inferred To

mia3 [endoplasmic reticulum lumen] (Xenopus tropicalis)

MIA3 [endoplasmic reticulum lumen] (Bos taurus)

MIA3 [endoplasmic reticulum lumen] (Canis familiaris)

MIA3 [endoplasmic reticulum lumen] (Gallus gallus)

MIA3 [endoplasmic reticulum lumen] (Sus scrofa)

Mia3 [endoplasmic reticulum lumen] (Mus musculus)

Mia3 [endoplasmic reticulum lumen] (Rattus norvegicus)

Tango1 [endoplasmic reticulum lumen] (Drosophila melanogaster)

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95833 CLIC3			0.556	3
UniProt:Q96PV6 LENG8			0.556	3
UniProt:Q9NSC5 HOMER3	1	HOMER3 [cytosol] (R-HSA-6794236)	0.556	3
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.556	3
UniProt:Q15436 SEC23A	4	SEC23A [endoplasmic reticulum membrane] (R-HSA-203976) SEC23A [cytosol] (R-HSA-203972) SEC23A [ER to Golgi transport vesicle membrane] (R-HSA-204024) p-S738,T744 SEC23A [cytosol] (R-HSA-5685740)	0.556	3
UniProt:Q02388 COL7A1	20	3x4Hyp-3Hyp-5Hyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605704) 5Hyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605706) 3x4Hyp-3Hyp-COL7A1(2822-2944) [extracellular region] (R-HSA-3605690) 3x4Hyp-5Hyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605707) 3x4Hyp-3Hyp-GalHyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605709) COL7A1(2822-2944) [extracellular region] (R-HSA-3605694) 3x4Hyp-GlcGalHyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605696) 3x4Hyp-GalHyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605698) 3x4Hyp-COL7A1(2822-2944) [extracellular region] (R-HSA-3605699) 3x4Hyp-3Hyp-GlcGalHyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605700) GlcGalHyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605687) GalHyl-COL7A1(2822-2944) [extracellular region] (R-HSA-3605703) COL7A1 [extracellular region] (R-HSA-2127487) 3x4Hyp-3Hyp-GlcGalHyl-COL7A1 [extracellular region] (R-HSA-2127471) GalHyl-COL7A1 [extracellular region] (R-HSA-2127517) 3x4Hyp-3Hyp-COL7A1 [extracellular region] (R-HSA-2127485) 3x4Hyp-COL7A1 [extracellular region] (R-HSA-2127530) 3x4Hyp-5Hyl-COL7A1 [extracellular region] (R-HSA-2127496) GlcGalHyl-COL7A1 [extracellular region] (R-HSA-2127478) 3x4Hyp-3Hyp-5Hyl-COL7A1 [extracellular region] (R-HSA-2127525)	0.524	2
UniProt:Q9BPX1 HSD17B14	1	HSD17B14 [cytosol] (R-HSA-6810587)	0.488	2

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