Reactome | HSD17B14 [cytosol]

HSD17B14 [cytosol]

Stable Identifier

R-HSA-6810587

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

17-beta-hydroxysteroid dehydrogenase 14, DHB14_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BPX1 HSD17B14

Gene Names

HSD17B14, DHRS10, SDR3, SDR47C1, UNQ502/PRO474

Chain

chain:1-270

Reference Genes

BioGPS Gene:51171 HSD17B14

COSMIC (genes):HSD17B14 HSD17B14

CTD Gene:51171 HSD17B14

dbSNP Gene:51171 HSD17B14

ENSEMBL:ENSG00000087076 HSD17B14

ENSEMBL_homo_sapiens_GENE:ENSG00000087076.9 HSD17B14

HGNC:23238 HSD17B14

KEGG Gene (Homo sapiens):51171 HSD17B14

Monarch:51171 HSD17B14

NCBI Gene:51171 HSD17B14

OMIM:612832 HSD17B14

UCSC:Q9BPX1 HSD17B14

Reference Transcript

RefSeq:NM_016246.2 HSD17B14

Other Identifiers

11720588_a_at

11757575_x_at

16874097

219113_PM_x_at

219113_x_at

224494_PM_x_at

224494_x_at

224497_PM_x_at

224497_x_at

228713_PM_s_at

228713_s_at

3867444

3867445

3867446

3867447

3867448

3867449

3867451

3867452

3867454

3867455

3867456

3867457

43419_s_at

51171

65515_at

8038213

A_23_P78762

GE58712

GO:0003824

GO:0004303

GO:0005515

GO:0005737

GO:0005829

GO:0006629

GO:0006706

GO:0008202

GO:0016491

GO:0042802

GO:0047045

HMNXSV003044223

ILMN_1809483

TC19001699.hg

g13623365_3p_s_at

Participates

as a component of

HSD17B14 tetramer [cytosol] (Homo sapiens)

Inferred To

hsd17b14 [cytosol] (Danio rerio)

hsd17b14 [cytosol] (Xenopus tropicalis)

HSD17B14 [cytosol] (Bos taurus)

Hsd17b14 [cytosol] (Mus musculus)

Hsd17b14 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_057330.2

OpenTargets

ENSG00000087076

IntEnz

1.1.1.62

GeneCards

Q9BPX1

HPA

ENSG00000087076-HSD17B14

Ensembl

ENST00000263278, ENSP00000263278, ENSG00000087076

PRO

Q9BPX1

Pharos - Targets

Q9BPX1

HMDB Protein

HMDBP08862

PDB

6GTU, 1YDE, 6G4L, 6GBT, 6EMM, 6QCK, 6ZR6, 6HNO, 5JS6, 5O6O, 5L7T, 5EN4, 5O6Z, 5JSF, 5L7W, 5O72, 6ZRA, 5O6X, 6ZT2, 5ICM, 5O42, 6ZDE, 6GTB, 6FFB, 5L7Y, 6H0M, 5ICS, 5O43, 5HS6, 5O7C, 6ZDI

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35638 DDIT3	1	DDIT3 [nucleoplasm] (R-HSA-381110)	0.764	6
UniProt:Q9BX63 BRIP1	2	p-S990,Ac-K1249-BRIP1 [nucleoplasm] (R-HSA-5687710) BRIP1 [cytosol] (R-HSA-2564781)	0.666	4
UniProt:P29372 MPG	1	MPG [nucleoplasm] (R-HSA-49155)	0.666	4
UniProt:P25786 PSMA1	2	PSMA1 [nucleoplasm] (R-HSA-174333) PSMA1 [cytosol] (R-HSA-68724)	0.621	3
UniProt:Q5T2D3 OTUD3	1	OTUD3 [cytosol] (R-HSA-8873955)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q5JRA6 MIA3	3	MIA3 [endoplasmic reticulum membrane] (R-HSA-5689472) p-MIA3 [endoplasmic reticulum lumen] (R-HSA-8957064) MIA3 [endoplasmic reticulum lumen] (R-HSA-8956743)	0.488	2

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