Reactome | SLC39A5 [plasma membrane]

SLC39A5 [plasma membrane]

Stable Identifier

R-HSA-442360

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

hZIP5, Zinc transporter ZIP5, S39A5_HUMAN

Locations in the PathwayBrowser

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Transport of small molecules (Homo sapiens)

- SLC-mediated transmembrane transport (Homo sapiens)
  - Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
    - Metal ion SLC transporters (Homo sapiens)
      - Zinc transporters (Homo sapiens)
        
        Zinc influx into cells by the SLC39 gene family (Homo sapiens)
        
        hZIP5 mediates zinc uptake by cells (Homo sapiens)
        
        SLC39A5 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q6ZMH5 SLC39A5

Gene Names

SLC39A5, ZIP5

Chain

signal peptide:1-20, chain:21-540

Reference Genes

BioGPS Gene:283375 SLC39A5

COSMIC (genes):SLC39A5 SLC39A5

CTD Gene:283375 SLC39A5

dbSNP Gene:283375 SLC39A5

ENSEMBL:ENSG00000139540 SLC39A5

HGNC:20502 SLC39A5

KEGG Gene (Homo sapiens):283375 SLC39A5

Monarch:283375 SLC39A5

NCBI Gene:283375 SLC39A5

OMIM:608730 SLC39A5

UCSC:Q6ZMH5 SLC39A5

Reference Transcript

Other Identifiers

0006380037

11729744_a_at

1552281_3p_at

1552281_at

16752602

283375

3417499

3417501

3417502

3417503

3417506

3417507

3417508

3417509

3417511

3417512

3417513

3417514

3417515

3417517

3417519

3417520

3417521

3417523

3417524

64246_at

7956229

A_23_P98876

A_33_P3385006

GE491196

GO:0001654

GO:0003674

GO:0005385

GO:0005575

GO:0005576

GO:0005615

GO:0005886

GO:0005887

GO:0006810

GO:0006811

GO:0006829

GO:0006882

GO:0007049

GO:0007165

GO:0008150

GO:0008283

GO:0016020

GO:0016021

GO:0016323

GO:0022857

GO:0030001

GO:0030154

GO:0030509

GO:0042592

GO:0043226

GO:0046873

GO:0048856

GO:0055085

GO:0061351

GO:0070062

GO:0070315

GO:0071578

HMNXSV003011316

Hs2.32699.1.S1_3p_at

Hs2.32699.1.S1_3p_s_at

Hs2.32699.1.S1_3p_x_at

ILMN_1794951

PH_hs_0002754

TC12000508.hg

Cross References

RefSeq

NP_001128667.1, XP_011536500.1, NP_775867.2, XP_011536501.1, XP_011536503.1, XP_011536502.1, XP_005268860.1

Guide to Pharmacology - Targets

1184

OpenTargets

ENSG00000139540

GeneCards

Q6ZMH5

HPA

ENSG00000139540-SLC39A5

Ensembl

ENSP00000266980, ENSP00000405360, ENSG00000139540, ENST00000454355, ENST00000266980

PRO

Q6ZMH5

Pharos - Targets

Q6ZMH5

GlyGen

Q6ZMH5

HMDB Protein

HMDBP11938

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